Clin2
NCT07101107Possibly a fitRecruiting

Understanding social and brain responses in bipolar depression

Bipolar 1 DisorderControl Subjects

Part of Injuries & trauma, Mental health clinical trials.

This study looks at how people with bipolar depression and healthy volunteers process social situations and how their bodies respond. It may help researchers find better ways to support people with bipolar disorder.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
160 people
Ages
18 years to 65 years
Study type
Observational

Who can take part

  • You are between 18 and 65 years old.
  • You have been diagnosed with bipolar I disorder and are currently in a moderate or severe depressive episode without psychotic features.
  • You score at least 20 on a depression rating scale (MADRS).
  • You are able to have an MRI scan (no metal implants, no claustrophobia).
  • You do not have other major mental health conditions like schizophrenia, borderline personality disorder, or substance dependence (except tobacco).

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07221864Recruiting
Emotions and brain activity in bipolar disorder

This study uses brain scans to understand emotions in bipolar disorder. It compares people with bipolar who are currently depressed or in a mixed state to healthy volunteers, and involves up to two visits to the research center.

Tulsa, Oklahoma
NCT07033923Recruiting
Brain study of mood changes in depression and bipolar disorder

This study uses a mobile app and brain scans to understand day-to-day mood changes in people with depression or bipolar disorder. It may help doctors learn how to better predict and treat these conditions.

Paris, Paris
NCT03829787Recruiting
Study of attention and reward signals in bipolar disorder

This study looks at how people with bipolar disorder pay attention and respond to rewards, including whether anxiety or substance use is also present. It uses eye-tracking and related tests to better understand brain patterns that may affect mood and decision-making.

Cleveland, Ohio
NCT06740331Recruiting
Thinking and memory study for mood disorders

This study looks at how people with bipolar disorder or depression process social situations, memory, and thinking. It compares patients, their relatives, and healthy volunteers to better understand these conditions.

Reims
NCT00762866Enrolling by invitation
Study of mental health traits using genetic and brain measurements

This study collects information about mental health symptoms and body/genetic samples to better understand how different mental health conditions are related. Some people may also have brain scans (PET or MRI) if they can safely complete them.

Nashville, Tennessee
NCT07680153Recruiting· Phase 4
Brain stimulation for bipolar depression

This study tests a non-invasive brain stimulation technique to see if it can improve mood in people with bipolar disorder who are currently experiencing depression. It aims to understand how the brain's mood circuits work.

New York, New York

Hear when a new Control Subjects trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.