Clinical trials
Cannabis clinical trials
Below are recruiting cannabis clinical trials, each written for real people, not researchers. We’re tracking 156 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07340554Recruiting
Brain imaging study for teens who use cannabis
This study looks at the brains of teenagers who use cannabis using an MRI scanner. It aims to understand how cannabis affects the developing brain, which might help improve treatment options.
Indianapolis, IndianaAges 14–17 - NCT07523633RecruitingPhase 2
Semaglutide to help reduce cannabis use disorder
This trial tests whether a medication called semaglutide (used for weight management) can help adults with cannabis use disorder cut down or stop using cannabis. Researchers want to see if it reduces cravings and use while also monitoring overall health.
FrederiksbergAges 18–70 - NCT07157540Enrolling by invitation
Testing Cann'App for cannabis harm reduction
This study is testing a smartphone app called Cann'App to help people who use cannabis reduce related harms. It's only for people who are already in a larger cannabis study in Lausanne, Switzerland.
Lausanne, Vaud CantonAges 18 years+ - NCT05389930RecruitingPhase 2
Study how cannabis affects alcohol drinking
This Phase 2 study looks at whether using cannabis changes how much alcohol you drink. You may be able to take part if you’ve been drinking heavily and using cannabis recently and can meet health and screening requirements.
Providence, Rhode IslandAges 21–50 - NCT07434895RecruitingEarly Phase 1
Can CBD Change How You Use Cannabis?
This study looks at how taking CBD (a cannabis compound that doesn't get you high) affects your cannabis use. It is for healthy adults who use cannabis for recreational reasons, not for medical treatment.
Lexington, KentuckyAges 18–55 - NCT05445180Recruiting
Brain scan study of thinking in cannabis users with psychosis
This study uses brain imaging to understand how thinking works in people who use cannabis, comparing those with psychosis to people without psychosis. It may help researchers learn what brain patterns relate to thinking difficulties and how cannabis use fits in.
Montreal, QuebecAges 16–80 - NCT05999383RecruitingPhase 2
Marijuana and tobacco use study
This trial looks at how marijuana and tobacco work together in your body. If you regularly use both cannabis and tobacco, you may help researchers understand their combined effects.
San Francisco, CaliforniaAges 21–65 - NCT06293040RecruitingPhase 1
Cannabis and Alcohol Impairment Study
This study tests how vaporized cannabis and alcohol together affect your ability to drive or perform tasks. It is for healthy adults who have used both substances before.
Baltimore, MarylandAges 21 years+ - NCT06601218RecruitingPhase 1
Daily oral cannabis for cancer patients with solid tumors
This trial tests whether taking a daily oral cannabis (marijuana) dose is safe for people with advanced solid tumors (cancer that has spread). It's looking for people who are already on a stable cancer treatment and want to see if adding cannabis affects their symptoms or how they feel.
Lexington, KentuckyAges 18 years+ - NCT07091292Recruiting
Exercise as a treatment for cannabis use
This study tests whether regular exercise can help young adults reduce or stop their cannabis use. It may be a good fit if you are 18-40, use cannabis as your main drug, and want to try an exercise-based approach.
Hong KongAges 18–40 - NCT07105449Recruiting
Testing high-potency cannabis concentrates in regular users
This study looks at how high-potency cannabis concentrates affect people who already use cannabis a few times a week. You will be asked to vape a concentrate and then have your reactions monitored.
Toronto, OntarioAges 19–55 - NCT06259916Recruiting
EEG to tell alcohol vs. cannabis intoxication
This study uses electroencephalography (EEG) to see if brain activity can tell whether you are drunk, high, or both. Results might help improve safety in the future.
Fort Collins, ColoradoAges 21–50 - NCT03909477Recruiting
Study of MRI brain scans in cannabis smokers over time
This study follows people who currently or used to smoke cannabis to see how cannabis use may change certain MRI scan signals in the brain over time. You may help researchers understand the effects of cannabis smoking and how brain imaging changes can be measured safely.
London, OntarioAges 18–85 - NCT06124846Recruiting
Cannabis break and brain changes in teens
This study looks at what happens in the brain when teens with cannabis use disorder stop using cannabis for 6 weeks. It uses MRI scans to see changes in areas that control habits and decisions.
Minneapolis, MinnesotaAges 15–18 - NCT07644052RecruitingPhase 3
A medication to ease cannabis withdrawal symptoms
This study tests whether a medication called PP-01 can help reduce cravings and uncomfortable symptoms when people stop using cannabis. If you're a heavy cannabis user who wants to quit and experiences withdrawal symptoms, this trial may help you manage the difficult transition.
Little Rock, ArkansasAges 18–55 - NCT06576076Recruiting
Cannabis, emotions, and risk study for teens
This study explores how daily cannabis use affects emotions and risk behaviors in teenagers. You'll answer quick surveys on your phone and wear a Fitbit for up to 3 months.
Boston, MassachusettsAges 12–18 - NCT05602649RecruitingPhase 1
How cannabis edible type changes drug levels in your body
This Phase 1 study tests how different cannabis edible formulations affect how THC shows up in your blood and how your body responds. It may help researchers choose safer, more predictable edible products based on how people absorb and react to them.
Baltimore, MarylandAges 21–55 - NCT06891235Recruiting
Testing cannabis use with mouth swabs
This study tests whether mouth swabs can detect recent cannabis use. If you use cannabis at least once a week and are between 18 and 30, you may be able to join.
Boston, MassachusettsAges 18–30 - NCT05526196Recruiting
Study how cannabis and tobacco affect reaction and feelings
This study tests how cannabis and tobacco—used together or separately—affect your thinking speed, how you feel, and body responses. You may help researchers understand these effects under controlled conditions, which could be useful for safer use and treatment decisions.
Toronto, OntarioAges 19–45 - NCT04325958Recruiting
Test how cannabis affects driving in different age groups
This study looks at how smoked cannabis changes driving performance when compared across two age groups. It may help researchers understand safety risks and differences by age.
Toronto, OntarioAges 19–45 - NCT04816994RecruitingPhase 3
Cannabis extract for nerve back pain and painkiller needs
This trial studies whether a cannabis extract can reduce acute nerve-related pain in the back and lessen how much pain medication you need. It may help people with a short-term episode of “shooting” nerve pain from the spine.
JerusalemAges 18–70 - NCT05401929Recruiting
TMS to reduce cannabis use in heavy users
This study tests whether transcranial magnetic stimulation (TMS) can help heavy cannabis users cut down or stop. TMS uses a magnetic coil on the scalp to gently stimulate parts of the brain involved in cravings and habits.
Durham, North CarolinaAges 18–65 - NCT04982965RecruitingEarly Phase 1
Study brain changes behind cannabis pain relief
This early study looks at how the brain may respond to cannabis to reduce long-lasting lower back pain. You may be asked to follow strict rules about cannabis, opioids, and safety checks (including MRI) to help researchers understand the brain mechanisms.
La Jolla, CaliforniaAges 21–65 - NCT06225232RecruitingPhase 2
Psilocybin for cannabis use disorder
This trial tests whether a single dose of psilocybin (a psychedelic compound) can help people with moderate to severe cannabis use disorder reduce or stop their cannabis use. You will receive the drug in a supervised setting and have follow-up check-ins.
Hamilton, OntarioAges 18–65
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Cannabis trials by city
Studies with a site in or near these metro areas.
Cannabis trials by state
Studies with a site anywhere in these states.
Common questions
- Are there clinical trials for cannabis?
- Yes. Clin2 currently lists 156 recruiting cannabis studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cannabis trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cannabis trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.