Clinical trials
Cannabis Use Disorder, Moderate clinical trials
Below are recruiting cannabis use disorder, moderate clinical trials, each written for real people, not researchers. We’re tracking 61 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07184983Recruiting
Brain stimulation for cannabis use disorder
This study tests whether a gentle brain stimulation technique (called tDCS) can help people who want to cut down or stop using cannabis. You'll wear a headband-like device during sessions at NYU, and the study team will check in with you over time.
New York, New YorkAges 22–65 - NCT06575751RecruitingPhase 2
Study of cannabidiol and cannabis concentrate users
This study looks at how cannabidiol (a compound in cannabis) affects people who regularly use strong cannabis concentrates like wax, shatter, or oil. It may help understand if using CBD can change how cannabis affects the body or help with cannabis use disorder.
Aurora, ColoradoAges 25–60 - NCT06569394RecruitingPhase 2
Testing CBD in young adults who use cannabis heavily
This study tests whether cannabidiol (CBD) can help young adults who use cannabis heavily but aren't looking to quit. You'll take a CBD pill and see if it changes your cannabis use or related symptoms.
Aurora, ColoradoAges 18–25 - NCT04871048Recruiting
tDCS training to reduce cannabis use in people with schizophrenia
This trial tests whether a non-painful brain stimulation method (tDCS) can help people with schizophrenia who also have moderate-to-severe cannabis use disorder reduce or quit cannabis. It also involves MRI scanning to help study brain changes.
BronAges 18–60 - NCT06981195RecruitingPhase 2
Testing lemborexant for insomnia in people on buprenorphine
This study tests if the sleep medication lemborexant can help people with opioid use disorder who also have chronic insomnia. Participants must already be taking buprenorphine (Suboxone) for at least 4 weeks. The goal is to see if better sleep improves mood and reduces opioid use.
Richmond, VirginiaAges 18 years+ - NCT06878859Recruiting
Online program for depression and cannabis use
This study tests a digital (online) program designed to help people who struggle with both depression and cannabis use. If you're feeling down and also using cannabis more than you'd like, this program might help you manage both.
Boston, MassachusettsAges 18 years+ - NCT06660381RecruitingPhase 1
Psilocybin therapy for cannabis use disorder
This study tests if psilocybin (a substance that can change how you think and feel) can help people reduce or stop using cannabis. You will receive support and be monitored closely throughout the trial.
Baltimore, MarylandAges 18 years+ - NCT06107062RecruitingPhase 2
CBD treatment for cannabis concentrate users
This trial tests CBD as a potential treatment for heavy cannabis concentrate users who want to cut down or quit. You would take CBD daily and attend regular visits to track your progress.
Boulder, ColoradoAges 21 years+ - NCT05999383RecruitingPhase 2
Marijuana and tobacco use study
This trial looks at how marijuana and tobacco work together in your body. If you regularly use both cannabis and tobacco, you may help researchers understand their combined effects.
San Francisco, CaliforniaAges 21–65 - NCT05957848RecruitingPhase 2
Guanfacine for teens with cannabis use problems
This Phase 2 study tests whether extended-release guanfacine can reduce cannabis use in adolescents and young adults. It may help by targeting brain pathways that can drive cravings or continued use.
Parkville, VictoriaAges 12–25 - NCT05859347Recruiting
Brain stimulation study for cannabis use disorder
This trial tests whether a treatment called repetitive transcranial magnetic stimulation (a non-surgical magnetic stimulation to the brain) can help people reduce or stop cannabis use. You may be eligible if you have cannabis use disorder and meet specific safety and symptom criteria.
Toronto, OntarioAges 18–65 - NCT05472818RecruitingEarly Phase 1
Imaging study for treating cannabis use disorder with a test dose
This early-phase study uses brain scans to study cannabis use disorder and looks at whether a treatment approach is suitable for people who use cannabis every day. It may help researchers understand brain changes related to quitting and recovery.
New Haven, ConnecticutAges 18–75 - NCT07644052RecruitingPhase 3
Study of a new medicine to ease cannabis withdrawal
This study tests a new medicine, PP-01, to help adults who use cannabis daily and want to quit. It aims to reduce withdrawal symptoms like anxiety, irritability, and sleep problems during the first week after stopping.
Little Rock, ArkansasAges 18–55 - NCT07420283RecruitingPhase 2
Study of Brenipatide for opioid use disorder
This trial tests a new medicine called Brenipatide for people with opioid use disorder who are already taking buprenorphine but still occasionally use non-prescribed opioids. It aims to see if the study drug can help reduce opioid use.
Phoenix, ArizonaAges 18–75 - NCT07218471Recruiting
Cannabis reduction study for heavy users
This study tests if helping people reduce heavy cannabis use improves daily life. It's for adults with cannabis use disorder who want to cut back.
Charleston, South CarolinaAges 18 years+ - NCT06907979Recruiting
Cannabis use and emotion processing study
This study looks at how heavy cannabis use affects the way you process emotions. You may be able to join if you use cannabis most days, meet criteria for cannabis use disorder, and are not currently in treatment for it. Participants will have brain scans and mild brain stimulation.
Auburn, AlabamaAges 18–50 - NCT07044466Recruiting
Social functioning study for people in treatment for opioid use
This study looks at how people recovering from opioid use disorder get along with a close friend or family member (called a CSO). It may help improve social support during early treatment.
Charleston, South CarolinaAges 18 years+ - NCT06994338RecruitingPhase 2
Tirzepatide for alcohol use disorder
This study tests whether a medication called tirzepatide (a once-weekly injection) can help people reduce their alcohol consumption. It is for people who drink heavily, have a high BMI, and are actively seeking help to drink less.
Los Angeles, CaliforniaAges 21–65 - NCT07464613Recruiting
Social thinking in severe alcohol use disorder
This study looks at how people with severe alcohol use disorder process social information, like understanding others' emotions or intentions. It uses brain imaging (MRI) and tests on a smartphone. The goal is to learn more about social cognition in recovery.
Reims, ReimsAges 18–65 - NCT07612631RecruitingEarly Phase 1
Brain imaging study of alcohol and stress response
This research uses brain imaging to understand how two brain systems—one involved in stress and one involved in reward—interact in people with alcohol use disorder. The goal is to find new ways to help people reduce heavy drinking.
Pittsburgh, PennsylvaniaAges 18–55 - NCT06381180RecruitingPhase 1/Phase 2
Cannabis for Veterans with PTSD
This study is testing whether cannabis can help veterans with PTSD feel better. It is for veterans who have used cannabis before and currently have PTSD symptoms.
Detroit, MichiganAges 19–69 - NCT06320366Recruiting
Faster TMS for methamphetamine use disorder
This study tests a faster brain stimulation technique (TMS) to help people reduce methamphetamine use. It may be a good option if you have moderate to severe methamphetamine use disorder and are looking for new treatment approaches.
Aurora, ColoradoAges 21–65 - NCT07490600Recruiting
Testing brain stimulation and rewards for quitting cocaine
This trial combines deep transcranial magnetic stimulation (TMS) with a reward program (contingency management) to help people stop using cocaine. It may help if you are struggling with moderate to severe cocaine use and want a non-drug treatment.
Houston, TexasAges 18–65 - NCT05011760RecruitingEarly Phase 1
PET brain scan with a cocaine-use disorder medicine test
This early-phase study uses a PET brain scan (a special imaging test) to see how the brain responds in people with cocaine use disorder. It aims to better understand brain activity and whether this scan approach could help research or future treatments.
Pittsburgh, PennsylvaniaAges 18–55
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Common questions
- Are there clinical trials for cannabis use disorder, moderate?
- Yes. Clin2 currently lists 61 recruiting cannabis use disorder, moderate studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cannabis use disorder, moderate trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cannabis use disorder, moderate trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.