Clinical trials · California
Cataract clinical trials in California
We’re tracking 14 recruiting cataract studies with a site in California — including Phase 3 and Phase 4 studies, each written for real people, not researchers.
Recruiting studies in California
- NCT07468877Recruiting
Comparing two cataract surgery systems for bilateral cataract removal
This trial compares two machines used during cataract surgery to see which one uses less energy and ultrasound time. If you are healthy and need cataract surgery in both eyes, this study might help determine the best approach.
Los Angeles, CaliforniaAges 18 years+ - NCT07589894Enrolling by invitation
Vision outcomes after cataract surgery with TruPlus lenses
This study measures how well people see after cataract removal surgery using a special TruPlus intraocular lens (an artificial lens placed in the eye). Researchers want to understand if this lens helps patients see clearly at distance with minimal side effects.
Encino, CaliforniaAges 50–80 - NCT07715591Recruiting
Relaxing breathing during awake cataract surgery
This study tests a special breathing and pain education program to help you stay calm and comfortable during cataract surgery while you are awake. It may reduce pain and anxiety without extra medicine.
Los Angeles, CaliforniaAges Any age - NCT07317661Enrolling by invitation
LLM-based app for cataract lens choice education
This trial studies whether a large language model (an AI tool) can help explain intraocular lens options to patients before cataract surgery. If you're planning your first cataract surgery, you may be able to join.
Palo Alto, CaliforniaAges 18 years+ - NCT05157113RecruitingPhase 4
After cataract surgery, a drop-free medicine plan
This trial studies whether a “drop-free” medication plan after cataract surgery works well and is practical for people receiving care at a county hospital. It may help reduce the need for multiple eye drops after surgery while still protecting the eye as it heals.
San Francisco, CaliforniaAges 18 years+ - NCT05191706RecruitingPhase 4
Check how safe DEXYCU is after childhood cataract surgery
This trial studies whether DEXYCU is safe to use to reduce eye inflammation after cataract surgery in children. It aims to see if the medicine’s side effects are acceptable and whether it helps during normal recovery.
Huntington Beach, CaliforniaAges Up to 3 years - NCT05980117RecruitingPhase 4
Remimazolam sedation for cataract surgery
This study tests a sedative, remimazolam, for older adults having their first cataract surgery. It aims to see if it helps keep patients comfortable and calm without needing general anesthesia.
Los Angeles, CaliforniaAges 65 years+ - NCT06383273RecruitingPhase 3
Study of MELT-300 for sedation during cataract surgery
This trial tests a new sedative medication, MELT-300, to help you relax during cataract surgery. It's for people having surgery on one eye and aims to see if it works better than standard care.
Chico, CaliforniaAges 18–65 - NCT01403402Recruiting
Study of congenital muscle disease patients and their families
This trial collects health information from patients with certain inherited (genetic) muscle diseases and from their families. It may help researchers better understand the disease and improve care by learning what symptoms and treatments patients experience over time.
Lakewood, CaliforniaAges Any age - NCT07006428Recruiting
Comparing two types of multifocal lens implants for cataract surgery
This trial compares the Clareon PanOptix lens with another similar multifocal lens to see which provides better vision after cataract surgery. It has two stages: one for people who already had the lenses implanted, and one for those who are planning to have cataract surgery.
Torrance, CaliforniaAges Any age - NCT03047369Recruiting
Myelin brain disorder research biobank for samples and data
This study collects brain-related medical information and biological samples to help researchers better understand leukodystrophies and other white-matter brain disorders. It may help future diagnosis and treatments by building a valuable “biobank” of patient data and samples.
Los Angeles, CaliforniaAges Any age - NCT04553523Recruiting
Hydrus microstent study for open-angle glaucoma with cataracts
This study enrolls people who have cataracts and primary open-angle glaucoma that is being treated with eye drops. It will look at how well the Hydrus microstent works after approval, especially for lowering eye pressure safely.
Irvine, CaliforniaAges 45 years+ - NCT06060041Recruiting
Study of the IC-8 Apthera lens after cataract surgery
This study is for people who already have an IC-8 Apthera lens in one eye and need treatment for clouding on the lens capsule (posterior capsule opacification). It evaluates how well this lens works over time.
Newport Beach, CaliforniaAges 22 years+ - NCT07480343Enrolling by invitation
Five-year follow-up after CREST glaucoma study
This study follows up with people who finished the CREST study to check how their eyes are doing 5 years later. It looks at the long-term results of a prior glaucoma treatment.
Newport Beach, CaliforniaAges Any age
Cataract trials by city in California
Where these studies are running in California
Institutions with a site for the recruiting cataract studies listed above.
- Advanced Vision Care
- Byers Eye Institute at Stanford University
- Children's Hospital Los Angeles
- Children's Hospital of Orange County
- Colvard-Kandavel Eye Center
- Congenital Muscle Disease International Registry (www.cmdir.org)
- CREST Site 05
- Doris Stein Eye Research Center
What taking part in a cataract study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Cataract trials in other states
Common questions
- Are there cataract clinical trials in California?
- Yes. We're currently tracking 14 recruiting cataract studies with a site in California, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a cataract study in California?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in California to take part?
- Not necessarily. These studies have a site in California, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a cataract trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New cataract studies open in California regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.