Clinical trials
Children With Medical Complexity clinical trials
Below are recruiting children with medical complexity clinical trials, each written for real people, not researchers. We’re tracking 22 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06375369Recruiting
Digital Health Program for Children with a New Tracheostomy
This study tests a digital health program for children with complex medical needs who have a tracheostomy. The program helps families and doctors manage care at home.
Calgary, AlbertaAges Up to 18 years - NCT04867395Recruiting
Hospital-to-home program for children with complex medical needs
This study tests a “hospital-to-home” transition plan to help children with complex medical needs safely manage care at home after discharge. You may be randomly placed into the program or usual care to see which better supports families.
New York, New YorkAges 18 years+ - NCT06216548Recruiting
E-PRIME for children with complex medical needs
This study tests a new program called E-PRIME to help children with complex medical needs and their families. It focuses on improving care coordination and may be a good fit if your child sees many specialists or depends on medical devices.
Winston-Salem, North CarolinaAges Up to 17 years - NCT06599398Recruiting
Bridge from hospital to home for kids with complex health needs
This study tests a program to help children with long-term, complex medical conditions and their families transition from hospital to home. It aims to make discharge safer and easier by addressing medical, care, and family needs.
AmsterdamAges birth–18 years - NCT06883045Recruiting
A mobile health program for kids with complex medical needs
This trial tests a program that uses a smartphone or tablet to help parents and children with complex medical needs manage care at home. If your child has multiple chronic conditions, sees several doctors, or uses a medical device, this may be a good fit.
Chicago, IllinoisAges 1–18 - NCT06444282Enrolling by invitation
Emergency action plans for infants with complex medical needs
This trial tests an emergency care plan for babies with serious, long-term health conditions. It aims to help families and doctors give better care during emergencies.
Burlington, VermontAges Up to 6 months - NCT06364514Recruiting
Antibiotic course study for kids with complex medical needs
This study looks at how long children with complex medical conditions need to take antibiotics for pneumonia. The goal is to find a patient-centered approach to treatment that works best for each child.
Boston, MassachusettsAges 2–25 - NCT06525818Recruiting
E.A.T. study: Helping kids with feeding tubes eat by mouth
This study tests a new program to help children under 3 who have both a feeding tube and a tracheostomy start eating by mouth. The program provides support and training for families at home.
Chicago, IllinoisAges Up to 3 years - NCT05881031Recruiting
Home breathing support for medically complex children
This trial studies whether starting a noninvasive breathing machine (given without a tube in the airway) at home works well and is tolerated in children with medical complexity. It may help improve comfort and safety when new breathing support is prescribed.
Toronto, OntarioAges 5 years–17.9 years - NCT07167927Recruiting
Decision support tool for children with neuromuscular scoliosis
Researchers are developing a decision support tool to help parents and doctors make decisions about surgery for children with neuromuscular scoliosis. The tool aims to provide clear information and support during the consultation.
Los Angeles, CaliforniaAges 8 years+ - NCT07102433Recruiting
Complex care for children with life-limiting conditions
This study aims to better understand the complex needs of children with life-limiting conditions and the support they receive. It involves interviews and workshops with children, parents, and professionals to improve care.
BirminghamAges 5 years+ - NCT07060300Enrolling by invitation
Genetic testing for drug reactions in complex care children
This study looks at how children with complex medical conditions respond to medicines based on their genes. It may help personalize care by testing how your child's body processes certain drugs, all from a simple cheek swab.
Cincinnati, OhioAges Any age - NCT05814497Recruiting
Brain scan study of how kids process chronic pain
This study looks at how the brain processes pain sensations in children with certain long-lasting pain conditions. It may help researchers understand what’s happening in the nervous system and guide better treatments.
Cincinnati, OhioAges 10–17 - NCT02852031Recruiting
Care program for newborns needing the Norwood procedure
This trial focuses on improving care for babies born with certain complex heart conditions where only one pumping chamber works. It is meant for babies (including unborn babies) who are planned to have the Norwood procedure, which is a common early surgery.
Birmingham, AlabamaAges Up to 1.3 years - NCT06903052Recruiting
App for parents managing child's breathing tube symptoms
This trial tests a mobile app that helps parents care for their child who needs a breathing tube at home. The app provides support and tips for managing symptoms, so parents feel more confident and prepared.
Kowloon, KowloonAges 2–18 - NCT05781152RecruitingPhase 4
Testing how new Crohn’s imaging and scopes predict outcomes
This study follows children newly diagnosed with Crohn’s disease to see how results from scans and endoscopy (camera scope) relate to outcomes over the first year. It may help doctors choose better early treatment plans and monitor children more effectively.
Phoenix, ArizonaAges 6–17 - NCT07045545Enrolling by invitation
Comparing two layers in hypospadias repair for young boys
This trial tests two ways to add an extra layer during hypospadias repair surgery in young boys. One method uses a material made from your child's own blood (platelet-rich fibrin), and the other uses a small flap of tissue from the penis. The goal is to see which method helps the healing better.
Tashkent, CityAges Any age - NCT06105736Recruiting
Online behavior program for children with tuberous sclerosis
This study tests a program called 'Regulating Together' for children with tuberous sclerosis complex who have behavior challenges. The program is done online with your child and you, and may help improve self-control and reduce outbursts.
Carrboro, North CarolinaAges 8–17 - NCT03838107Recruiting
Tracking changes in pediatric CRPS using study markers
This study looks at how signs in the body change over time in children with CRPS (complex regional pain syndrome). It mainly involves being assessed alongside the usual CRPS care, and often includes MRI checks to better understand the pain course.
Cincinnati, OhioAges 10–17 - NCT06742528Recruiting
Comparing two iron medicines for children with low iron
This study compares two iron medicines—one a simple iron pill and the other a gentle iron form—to see which works better for children with low iron levels (anemia). If your child has iron deficiency anemia and none of the listed health issues, they may be able to join.
Peshawar, KPKAges 6 months–5 years - NCT06489093RecruitingEarly Phase 1
Silver agents for early cavities in children's baby teeth
This study checks if silver-containing agents can help heal early white spots (cavities) on baby teeth of children aged 3 to 8. It compares different silver treatments to see which works best for stopping or reversing these early cavities.
PlovdivAges 3–8 - NCT07465614Recruiting
Nerve stimulation study for children with cyclic vomiting syndrome
This study tests whether a gentle nerve stimulation device placed on the ear can reduce vomiting episodes in children with cyclic vomiting syndrome (CVS). It aims to find a safe, non-drug option for managing symptoms.
Milwaukee, WisconsinAges 5–18
Hear when a new Children With Medical Complexity trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for children with medical complexity?
- Yes. Clin2 currently lists 22 recruiting children with medical complexity studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a children with medical complexity trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a children with medical complexity trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.