Clinical trials · Missouri
Crohn’s disease clinical trials in Missouri
We’re tracking 24 recruiting crohn’s disease studies with a site in Missouri — including Phase 1, Phase 1/Phase 2, Phase 2, Phase 3 and Phase 4 studies, each written for real people, not researchers.
Recruiting studies in Missouri
- NCT06226883RecruitingPhase 2
Testing MORF-057 for moderate to severe Crohn's disease
This study tests an oral medicine called MORF-057 for people with moderate to severe Crohn's disease. It aims to see if the drug can reduce inflammation and improve symptoms for those who haven't had success with other treatments.
Bridgeton, MissouriAges 18–85 - NCT07625293RecruitingPhase 2
DB-3Q for treatment-resistant Crohn's disease
This trial tests a new medicine called DB-3Q for people with Crohn's disease that hasn't responded to standard biologic treatments or causes side effects. The study aims to see if DB-3Q can reduce inflammation and symptoms in people whose disease is hard to control.
St Louis, MissouriAges 18–75 - NCT07577843RecruitingPhase 3
Testing JNJ-78934804 for moderate to severe Crohn's disease
This study tests a new drug called JNJ-78934804 for people with moderate to severe Crohn's disease who have not responded well to or can't tolerate current treatments. The goal is to see if this drug can reduce inflammation and symptoms in the digestive tract.
Lee's Summit, MissouriAges 18 years+ - NCT07483099RecruitingPhase 2
Study of two drugs for Crohn's disease
This trial tests if taking a new drug (LY4395089) with mirikizumab works better than mirikizumab alone for adults with Crohn's disease. It also looks at the safety of these treatments.
St Louis, MissouriAges 18–80 - NCT06976853RecruitingPhase 2
Testing a new drug for Crohn’s disease beyond inflammation
This study tests a medicine called tirzepatide to see if it can help people with active Crohn’s disease who have not responded to multiple prior treatments. It focuses on how the drug might work beyond just reducing inflammation.
St Louis, MissouriAges 18–80 - NCT06721962RecruitingPhase 1/Phase 2
Testing an experimental treatment for moderate to severe Crohn's disease
This trial is testing a new investigational treatment called TRX103 for adults with moderate to severe Crohn's disease that has not responded to at least two other advanced therapies. The study aims to see if this treatment can reduce inflammation and improve symptoms.
St Louis, MissouriAges 18–65 - NCT06958536RecruitingPhase 2
Study of brivekimig for moderate-to-severe Crohn's disease
This trial tests a new medicine called brivekimig for people with moderate-to-severe Crohn's disease. It aims to see if the drug can reduce symptoms and inflammation better than standard treatments.
St Louis, MissouriAges 18–75 - NCT07184944RecruitingPhase 3
Study of Duvakitug for moderate to severe Crohn's disease
This study tests a new drug called duvakitug to see if it can help maintain improvement in people with moderate to severe Crohn's disease. It's for patients who have already responded to treatment in a previous study.
Liberty, MissouriAges 16–80 - NCT07184931RecruitingPhase 3
Testing duvakitug for active Crohn's disease
This study tests a new drug called duvakitug for people with moderately to severely active Crohn's disease who haven't responded well to other treatments. It aims to see if the drug can reduce symptoms and improve quality of life.
Liberty, MissouriAges 16–80 - NCT06548542RecruitingPhase 2
Targeted drug study for moderate to severe Crohn's disease
This trial tests new targeted therapies for adults with moderate to severe Crohn's disease that hasn't improved with standard treatments. The goal is to see if these drugs can reduce inflammation and improve symptoms.
Columbia, MissouriAges 18–75 - NCT06233461RecruitingPhase 2
A study of TAK-279 for Crohn's disease
This study tests an oral medication called TAK-279 to see if it can safely reduce inflammation in the bowel for people with moderate to severe Crohn's disease who haven't had success with other treatments.
Liberty, MissouriAges 18–75 - NCT06045754RecruitingPhase 4
Study of vedolizumab with other drugs for Crohn's disease
This trial tests whether combining vedolizumab with adalimumab or ustekinumab helps people with moderate to severe Crohn's disease who haven't responded to other treatments. It aims to find better ways to manage symptoms and improve quality of life.
Kansas City, MissouriAges 18–70 - NCT07483073RecruitingPhase 2
Study of new drugs for moderate to severe ulcerative colitis or Crohn's disease
This trial is testing multiple new drugs for people with moderate to severe ulcerative colitis or Crohn's disease who have not had success with at least one standard treatment. The goal is to find a better option that can help control symptoms and inflammation.
St Louis, MissouriAges 18–80 - NCT04844606RecruitingPhase 3
Mirikizumab for kids with ulcerative colitis or Crohn’s
This study checks whether continuing mirikizumab (a medicine that calms gut inflammation) helps children with ulcerative colitis or Crohn’s disease after prior study treatment. It aims to see if staying on the medicine is beneficial and safe over time.
St Louis, MissouriAges 2–19 - NCT07697456RecruitingPhase 2
Study of advanced therapies for Crohn's or ulcerative colitis
This study tests advanced treatments for people with moderate to severe Crohn's disease or ulcerative colitis who haven't responded to at least one previous therapy. It aims to find better options for managing these conditions.
St Louis, MissouriAges 18–75 - NCT06430801RecruitingPhase 3
Study of tulisokibart for moderate to severe Crohn's disease
This trial tests a new medicine called tulisokibart for people with moderate to severe Crohn's disease. The medicine may help reduce inflammation and improve symptoms. It is for those who have not had success with other treatments.
Kansas City, MissouriAges 16–80 - NCT06819891RecruitingPhase 3
Study of afimkibart for active Crohn's disease
This trial tests a new medicine called afimkibart for people with moderately to severely active Crohn's disease that has not responded well to other treatments. It aims to see if the medicine can safely reduce inflammation and improve symptoms.
Columbia, MissouriAges 16–80 - NCT06937099RecruitingPhase 3
Testing two drugs for Crohn's with weight issues
This trial tests two study drugs, mirikizumab and tirzepatide, in people with moderate to severe Crohn's disease who also have overweight or obesity. The goal is to see if these treatments can help control Crohn's symptoms and inflammation.
St Louis, MissouriAges 18–70 - NCT06918808RecruitingPhase 2
Stem cell therapy for Crohn's fistula healing
This trial tests if a special stem cell treatment (called DB-3Q bmMSC-EVs) can help heal fistulas caused by Crohn's disease. It's for people who have already tried other treatments and still have actively draining fistulas.
St Louis, MissouriAges 18–75 - NCT06651281RecruitingPhase 3
Long-term safety and effectiveness of tulisokibart for Crohn's or colitis
This study gives tulisokibart to people who already took part in an earlier trial for Crohn's disease or ulcerative colitis and are still benefiting from it. The goal is to see how safe and effective the medicine is over a longer period.
Liberty, MissouriAges Any age - NCT03816345RecruitingPhase 1
Nivolumab for advanced cancer with autoimmune disease
This trial tests whether the immunotherapy drug nivolumab can safely treat advanced cancer in people who also have an autoimmune disease like rheumatoid arthritis, lupus, or multiple sclerosis. It aims to find out if the drug may help control cancer while managing their autoimmune condition.
City of Saint Peters, MissouriAges 18 years+ - NCT06581328RecruitingPhase 4
Study of vedolizumab for ulcerative colitis or Crohn's disease
This study tests a medication called vedolizumab for people with moderate to severe ulcerative colitis or Crohn's disease. The goal is to see how well it works in a regular community setting, and it may help control symptoms if other treatments haven't worked.
Bridgeton, MissouriAges 18–80 - NCT07113522RecruitingPhase 2
Study of new therapies for Crohn's and colitis
This trial tests new therapies for people with moderate to severe Crohn's disease or ulcerative colitis. It may help if your standard treatments aren't working well enough.
Bridgeton, MissouriAges 18–80 - NCT06670638Recruiting
New test for crohn's disease in people with a permanent ileostomy
This study aims to develop a new way to measure inflammation and symptoms in people with Crohn's disease who have a permanent ileostomy. Participants will undergo a routine ileoscopy and answer questions to help create better tools for future clinical trials.
St Louis, MissouriAges 18 years+
Crohn’s disease trials by city in Missouri
Where these studies are running in Missouri
Institutions with a site for the recruiting crohn’s disease studies listed above.
- Washington University in St. Louis · 6 studies
- BVL Clinical Research · 4 studies
- BVL Clinical Research-Site Number: 8400005 · 2 studies
- Gateway Gastroenterology-Site Number: 8400097 · 2 studies
- KAD Clinical Research · 2 studies
- Mid-America Gastro-Intestinal Consultants · 2 studies
- Specialists in Gastroenterology · 2 studies
- Washington University School of Medicine · 2 studies
What taking part in a crohn’s disease study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Crohn’s disease trials in other states
Common questions
- Are there crohn’s disease clinical trials in Missouri?
- Yes. We're currently tracking 24 recruiting crohn’s disease studies with a site in Missouri, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a crohn’s disease study in Missouri?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Missouri to take part?
- Not necessarily. These studies have a site in Missouri, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a crohn’s disease trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New crohn’s disease studies open in Missouri regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.