Clinical trials
Dengue clinical trials
Below are recruiting dengue clinical trials, each written for real people, not researchers. We’re tracking 28 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07409857Recruiting
Dengue infection in congenital bleeding disorders registry
This study creates a registry to track how dengue infection affects people with congenital bleeding disorders, such as hemophilia. It aims to learn more about managing dengue in this group.
BangkokAges Any age - NCT07602920Recruiting
Understanding Gut Leakage in Dengue Fever
This study investigates whether dengue fever causes the intestinal lining to become leaky, allowing harmful substances to enter the bloodstream. Researchers compare blood markers in dengue patients and healthy volunteers to understand how this happens and why it might make dengue worse.
Chittagong, Chattogram DivisionAges 18 years+ - NCT07007585Recruiting
Dengue care: who needs hospital or transfusion?
This study looks at why some people with dengue need to be hospitalized or get a blood transfusion. It aims to make care safer and help doctors know who needs closer monitoring.
Piedras Negras, CoahuilaAges 5 years+ - NCT04597437RecruitingPhase 2
Zanamivir for dengue that causes warning signs
This Phase 2 study tests whether zanamivir given through a vein can improve outcomes in people with dengue infection who have warning signs. It may help by reducing the body problems dengue can cause in blood vessels and fluid balance.
Barranquilla, AtlánticoAges 7 years+ - NCT06843226Recruiting
Dengue vaccine study for children and teens
This study tests if a dengue vaccine (TDV) can reduce hospital stays for dengue. It follows children and teens in areas where dengue vaccination is planned.
Banjarmasin, South KalimantanAges 6–12 - NCT07576868RecruitingPhase 2/Phase 3
Study of CP-COV03 Treatment for Dengue and Dengue-like Illness
This trial tests whether a new medicine called CP-COV03 can help people recover faster from dengue fever or dengue-like illness. You would receive either the study medicine or a placebo (inactive pill) and be monitored closely to see if symptoms improve.
HanoiAges 18 years+ - NCT06006559RecruitingPhase 2
Testing a new dengue treatment (EYU688) in adults
This trial tests a new experimental drug, EYU688, for adults with dengue fever. It aims to see if the drug is safe and effective. You may qualify if you have early dengue symptoms, have tested positive for dengue, and are otherwise healthy.
Manaus, AmazonasAges 18–60 - NCT07706686RecruitingPhase 1
Dengue challenge study in people with prior infection
This study tests how the body responds to a mild, lab-made dengue virus in people who have had dengue before. It looks at how the immune system reacts to a second infection, which may help improve future vaccines and treatments.
Bethesda, MarylandAges 18–50 - NCT06891950RecruitingPhase 3
Dengue vaccine study for healthy older adults
This trial tests a new dengue vaccine in adults aged 40 to 79 to see if it can protect them from dengue fever. If you are generally healthy and willing to follow the study schedule, you may be able to join.
Curitiba, ParanáAges 40–79 - NCT04486638Recruiting
Dengvaxia pregnancy registry in the US
This registry collects information about people who were pregnant and exposed to the Dengvaxia vaccine during pregnancy, to better understand outcomes after that exposure. It may help future mothers and clinicians by building a clearer safety and health record over time.
San JuanAges Any age - NCT04839757Recruiting
Testing a dengue vaccine plan for kids in the Caribbean
This trial looks at a dengue vaccine strategy in children ages 9 to 17 in Martinique and Guadeloupe. It may help protect kids from dengue, based on how the vaccine is accepted and how the study is carried out.
Fort-de-FranceAges 9–17 - NCT05631405Recruiting
Dexamethasone for serious dengue with warning signs
This trial studies whether dexamethasone (a steroid medicine) can help people with dengue infection who have warning signs and are still in the fever stage. It may help reduce complications like breathing problems, severe bleeding, or organ stress, but it is only for a specific window and situation.
BangkokAges 7–99 - NCT06551844RecruitingPhase 2
Adaptive platform trial for new dengue treatments
This trial tests different experimental drugs to treat dengue early. It aims to find which treatment works best and is safe for patients who start within 48 hours of fever.
Kuala LumpurAges 10 years+ - NCT06579755RecruitingPhase 3
Dengue vaccine study for adults aged 45 to 79
This study tests a dengue vaccine (TDV) in adults aged 45 to 79. It aims to see if the vaccine is safe and effective, even for people with common health conditions like diabetes or high blood pressure.
Buenos AiresAges 45–79 - NCT06665035RecruitingPhase 3
Dengue vaccine study for infants and toddlers
This trial tests two doses of a dengue vaccine in healthy infants and toddlers aged 6 to 21 months. It aims to see if the vaccine is safe and helps protect against dengue fever.
Barranquilla, AtlánticoAges 6 months–1.7 years - NCT06747130RecruitingPhase 2/Phase 3
Montelukast to Prevent Liver Enzyme Rise in Dengue
This trial tests if montelukast (a common asthma and allergy medicine) can help prevent liver enzyme increases in adults hospitalized with dengue fever. It may be a good option if you have typical dengue and are not too sick.
BangkokAges 20 years+ - NCT06751836Recruiting
New ways to treat severe dengue
This trial tests new strategies to treat dengue, ranging from mild to severe cases. It may help people with different stages of dengue find better care and support.
Guatemala CityAges 18 years+ - NCT06776692Recruiting
Dengue vaccine immunity study for all ages
This study looks at how the dengue vaccine works in people with and without past exposure to dengue or similar viruses like yellow fever or Zika. Volunteers receiving the dengue vaccine will give blood samples to help researchers understand the immune response.
Negrar, VRAges 4 years+ - NCT06894901Recruiting
Testing mosquito release to stop dengue clusters in public housing
This trial tests a new way to reduce dengue outbreaks by releasing special mosquitoes in public housing areas with active dengue clusters. If your neighborhood has a recent cluster of at least 10 cases, you may be part of the study.
SingaporeAges Any age - NCT07000747Recruiting
Dengue and sickle cell disease study
This study looks at how severe dengue fever affects people with sickle cell disease. It aims to understand why some people with sickle cell get very sick from dengue and how their cells react.
Pointe-à-PitreAges 6–25 - NCT07040202Recruiting
Immune responses in dengue and sepsis patients
This study looks at how the immune system responds to dengue fever and sepsis (a severe infection). It aims to better understand these illnesses, which could lead to improved treatments. If you have dengue-like symptoms, sepsis, or are a healthy volunteer, you may be able to join.
Kampong SpeuAges 2 years+ - NCT07087912RecruitingPhase 4
Dengue vaccine safety in people with autoimmune rheumatic diseases
This study tests the safety and immune response of a dengue vaccine in people aged 12–59 with stable autoimmune rheumatic diseases (like rheumatoid arthritis or lupus) who are on low-dose or no immune-suppressing medications. It also includes healthy volunteers for comparison.
São Paulo, São PauloAges 12–59 - NCT07412483Recruiting
Dengue infection study in healthy adults
This trial tests how the dengue virus affects healthy adults who have never been exposed to dengue or similar viruses. You would be given a controlled dose of the virus and closely monitored to help researchers understand the infection and develop better treatments or vaccines.
SingaporeAges 21–45 - NCT07172100Enrolling by invitationPhase 2
Papaya Leaf Extract for Kids with Dengue and Low Platelets
This trial tests if papaya leaf extract can help raise low platelet counts in young children with dengue fever. It may offer a natural way to reduce the risk of bleeding.
KarachiAges 2–12
Hear when a new Dengue trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for dengue?
- Yes. Clin2 currently lists 28 recruiting dengue studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a dengue trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a dengue trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.