Safety and effects of a weakened dengue virus in volunteers
Part of Infections clinical trials.
This study tests how the body reacts when volunteers are deliberately infected with a weakened version of the dengue virus. You will be closely monitored and this may help develop better vaccines for dengue.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Be 18 to 50 years old.
- Be in overall good health. Some chronic conditions (like high blood pressure above 180/110, or diabetes with HbA1c >8) are not allowed.
- Have no HIV, hepatitis B, or hepatitis C.
- Not be pregnant or breastfeeding (for those who can become pregnant, must use effective contraception).
- Agree not to receive other vaccines or travel to dengue-endemic areas during the study.
- You must have either never had dengue (or a similar virus) or have had dengue before, depending on the study group.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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