Clinical trials
Disease clinical trials
Below are recruiting disease clinical trials, each written for real people, not researchers. We’re tracking 9,578 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05427786RecruitingPhase 4
Nicotinamide-like heart medicine given during stent helps blood flow
This trial studies whether a medicine (nicorandil) given into a coronary artery during stent procedures can help keep blood flow from getting worse. It may help people having stent placement for coronary artery disease by improving how well blood moves through the treated area.
SeoulAges 19 years+ - NCT05434572Recruiting
Neuromuscular disease biobank for research samples
This trial is building a biobank (a secure research collection) from people with neuromuscular diseases, their families, or healthy volunteers. By joining, you help researchers study these conditions and improve future treatments.
Richmond, VirginiaAges Up to 75 years - NCT05437536Recruiting
Severe von Willebrand disease patient registry in the U.S.
This registry collects health and bleeding information from people who have severe von Willebrand disease (a lifelong bleeding condition). Your data helps researchers understand the condition better and supports future studies that may lead to better treatments.
Wellington, FloridaAges Any age - NCT05439863Recruiting
Valve procedure trial for severe aortic valve problems
This trial studies people with severe aortic valve disease who will receive a catheter-based valve replacement (TAVR). It aims to check how well this approach works for fixing a narrowed or leaky aortic valve, and to monitor outcomes afterward.
Nanjing, JiangsuAges 18 years+ - NCT05437965Recruiting
Registry study for repeat coronary blockages after stents
This study follows adults who have fast, unexplained re-narrowing of a coronary stent, to better understand what causes it and how to monitor it. You may help by allowing the study team to collect medical information over time.
Beijing, Beijing MunicipalityAges 18 years+ - NCT05444127Recruiting
Study of oral health in people with Wilson’s disease
This study compares oral (mouth and teeth) health in people with Wilson’s disease versus people without it. It aims to see whether Wilson’s disease is linked to specific dental and imaging findings, which could help with future prevention and care.
Ivry-sur-SeineAges 18 years+ - NCT05442567RecruitingPhase 3
Vedolizumab study for kids with ulcerative colitis or Crohn’s
This Phase 3 study tests whether vedolizumab can help children with ulcerative colitis (UC) or Crohn’s disease (CD) who improved on earlier treatment. It focuses on kids who can stay off steroid medicines and follow study visits and safety rules.
Mobile, AlabamaAges 2 years+ - NCT05443906Recruiting
Home exercise program for people with neurodegenerative conditions
This trial studies whether a home exercise program is safe and helpful for people with certain neurodegenerative conditions, including X-linked adrenoleukodystrophy and DARS2-related disease, as well as some other similar diagnoses. You would be asked to do exercises at home and be assessed on your walking and strength/safety.
Baltimore, MarylandAges 5–75 - NCT05444907Recruiting
Testing treatment response in DBS-related mania in Parkinson’s
This study is looking at people with Parkinson’s who developed mania (a high-energy mood episode) after deep brain stimulation (DBS) was turned on or its settings were changed. It may help doctors better understand why this happens and how to manage it safely.
LisbonAges 18 years+ - NCT05450991Recruiting
Study outcomes in children with Hirschsprung’s disease
This study looks at long-term health and development outcomes in children who were diagnosed and treated for Hirschsprung’s disease or anorectal malformations. It uses both numbers and interviews to understand what happens over time after treatment, helping families and clinicians plan better care.
Liverpool, MerseysideAges Any age - NCT05452356Recruiting
Testing a phone-based care plan for people with heart conditions
This trial tests a phone app that helps deliver organized “care plans” for people with cardiovascular (heart/vessel) conditions. You might join to see if this phone-based support improves how care is delivered and helps you manage your condition.
London, OntarioAges 18 years+ - NCT05461820RecruitingPhase 4
Testing treatment options for Graves’ disease and its relapse
This study compares different treatment plans to see how well they control Graves’ disease and whether it comes back. It may help by identifying which approach works best to prevent relapse.
NanjingAges 18–65 - NCT05465031RecruitingPhase 4
Testing heart-protection medicine during breast cancer treatment
This trial tests sacubitril/valsartan to help prevent heart weakness (cardiotoxicity) caused by breast cancer treatments like anthracyclines and/or anti-HER2 drugs. If you qualify, you may be offered this heart-protection medicine while your cancer is treated.
Opole, Opole VoivodeshipAges 18 years+ - NCT05465070Recruiting
Heat therapy trial for leg blood-flow problems
This trial studies whether applying heat to your legs can improve symptoms and function in people with peripheral artery disease (reduced blood flow to the legs). You may be tested with a simple blood-flow check and an MRI scan, depending on eligibility.
Indianapolis, IndianaAges 50 years+ - NCT05472207Recruiting
Risk check study for heart disease patients
This study looks at how to better sort people with heart disease into different risk groups. You may be asked for information about your heart condition and related health to help guide future care.
Innsbruck, TyrolAges 18 years+ - NCT05474417Recruiting
Study of how CF carrier status may affect organs
This study looks at whether people who carry one cystic fibrosis (CF) gene change have differences in the kidneys and pancreas. You may be able to help researchers learn early effects and better health monitoring for CF carriers.
Iowa City, IowaAges 18–100 - NCT05475015Recruiting
3D MRI scan to assess liver scarring and pressure
This study tests whether a special 3D MRI scan (3D-MRE) can measure liver scarring and the high pressure in the liver called portal hypertension. It may help your team use imaging to understand how severe your liver disease is, especially when a pressure test (HVPG) is being considered.
Shenyang, LiaoningAges 18–75 - NCT05478083RecruitingPhase 2
Leuprolide treatment for severe polycystic liver growth
This Phase 2 study tests whether a monthly hormone medicine (leuprolide, a GnRH agonist given as an injection) can slow down ongoing, fast-growing polycystic livers. It is aimed at pre-menopausal women with very large livers that are still getting bigger on past and current scans.
Nijmegen, GelderlandAges 18–45 - NCT05482126Recruiting
Studying brain sensing in advanced Parkinson’s during deep brain stimulation
This study looks at how the brain “filters” sensory information in people with advanced Parkinson’s disease, using brain imaging and deep brain stimulation (DBS) that you may already be getting as routine care. The goal is to better understand what drives Parkinson’s symptoms and how DBS might affect the brain.
Birmingham, AlabamaAges 18–89 - NCT05482607Recruiting
CT scan pattern study in lung disease from systemic sclerosis
This study looks at patterns seen on a high-resolution CT (HRCT) scan to better understand lung disease that can occur with systemic sclerosis. It may help doctors recognize which lung changes go with which type of disease.
NancyAges 18 years+ - NCT05493514Recruiting
Robotic training program for walking and balance
This trial studies whether a robotic training system (called G-EO) can help people with neurological conditions improve walking and balance. It may help by testing which factors predict who benefits most, and it requires regular training sessions.
MilanAges 18 years+ - NCT05493605Recruiting
MRI study of heart involvement in Wilson disease
This study looks at whether Wilson disease affects the heart, using MRI scans (and possibly contrast dye). Your results may help doctors better understand cardiac (heart) involvement and how it progresses in Wilson disease.
ParisAges 18 years+ - NCT05494060RecruitingPhase 2
Adjuvant chemo plus immunotherapy for ctDNA-positive stomach cancer
This trial tests whether adding an anti-cancer immune treatment and another targeted drug to standard chemotherapy after surgery can lower the chance of cancer coming back. It is for people whose blood test (ctDNA) shows leftover cancer-related DNA after surgery.
Nanjing, JiangsuAges 18–75 - NCT05500807RecruitingPhase 1
Emicizumab study for severe von Willebrand disease or overlap disorder
This Phase 1 trial studies how well and safely emicizumab works for people with severe von Willebrand disease (VWD) or VWD plus hemophilia A. Emicizumab is a preventive medicine given regularly to reduce bleeding risk.
Orange, CaliforniaAges birth–90 years
Hear when a new Disease trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for disease?
- Yes. Clin2 currently lists 9,578 recruiting disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.