Study of APAC for peripheral artery disease and severe leg ischemia
Treatments studied
Part of Heart & circulation clinical trials.
This trial tests a new drug called APAC to see if it safely prevents blood clots and improves blood flow in people with narrowed leg arteries. It may help those with severe symptoms like pain at rest or non-healing wounds, or those with claudication (leg pain when walking).
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are a man aged 45 to 85, or a woman past menopause (no period for at least a year) up to age 85.
- You have peripheral artery disease (PAD) with symptoms like leg pain at rest, skin wounds on the front of the foot, or pain when walking.
- You are already taking daily aspirin or clopidogrel for at least 5 days before starting the study drug.
- You are willing to have an imaging test like a CT or MRI angiogram showing blockages in your leg arteries below the knee.
- You are not on strong blood thinners (like warfarin or rivaroxaban) and have no history of bleeding problems or recent stroke.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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