Clinical trials
Early Psychosis clinical trials
Below are recruiting early psychosis clinical trials, each written for real people, not researchers. We’re tracking 22 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04411225RecruitingPhase 3
CBD may help early psychosis along with usual treatment
This Phase 3 trial tests whether taking cannabidiol (CBD) can reduce symptoms when added to standard care for early psychosis (like first-episode psychosis or attenuated psychosis). It may help some people have fewer troubling thoughts or perceptions over time.
La Jolla, CaliforniaAges 16–30 - NCT07417904Recruiting
Brave program for safety and violence risk in early psychosis
This trial tests a program called BRAVE to help young people with early psychosis learn skills to stay safe and reduce violence risk. It is for those already getting care at a clinic and considered stable enough to participate.
Washington D.C., District of ColumbiaAges 16–30 - NCT06740383Recruiting
Study of early psychosis and treatments
This study looks at people who have had psychosis for less than 4 years to understand how their symptoms change over time and how they respond to treatment. By using brain scans and other tests, researchers hope to find better ways to personalize care for early psychosis.
Hartford, ConnecticutAges 18–40 - NCT06071858Recruiting
Enhanced coordinated care for early psychosis
This trial studies an enhanced version of coordinated specialty care (CSC) for people experiencing their first episode of psychosis. It aims to improve outcomes by providing more intensive support and coordination among different healthcare providers.
Belmont, MassachusettsAges Any age - NCT07225179Recruiting
Mobile help for caregivers of young adults with early psychosis
This study tests a mobile app (Bolster) designed to support caregivers of young adults who have recently experienced psychosis. It aims to provide resources and connections to help you care for your loved one and yourself.
Chapel Hill, North CarolinaAges 18 years+ - NCT05796401RecruitingPhase 3
Personalized care program for early psychosis outcomes
This trial tests whether a personalized care plan improves day-to-day functioning for people in the early stages of psychosis. It aims to see if adding structured support after a recent diagnosis can help you function better.
BrestAges 15–30 - NCT07263022RecruitingPhase 3
Cognitive Training for Early Psychosis Study
This study tests whether a cognitive training program can help young adults with recent psychosis improve their thinking and memory skills. It involves brain scans and cognitive exercises.
Minneapolis, MinnesotaAges 18–35 - NCT07001878RecruitingPhase 4
Cannabis Strength and Brain Health in Early Psychosis
This trial studies how different strengths of cannabis affect the brain's white matter in people with early psychosis. It may help doctors understand which cannabis potencies are less harmful for young adults with psychosis.
St. John's, Newfoundland and LabradorAges 18–25 - NCT07056894Recruiting
Cognitive training for substance use in early psychosis
This study tests a computer-based cognitive training program to help people with early psychosis reduce their alcohol and cannabis use. The program is designed to improve thinking skills and may make it easier to cut back on substance use.
St. John's, Newfoundland and LabradorAges 16–30 - NCT06634446Recruiting
Self-guided cognitive training for early psychosis
This study tests a self-guided cognitive training program designed for young people who recently had their first episode of psychosis. It aims to improve thinking skills and daily function through exercises you can do at home.
ParisAges 16–35 - NCT06774417Recruiting
Digital strategies to help young people seek help for mental health
This trial tests a digital tool designed to help young people recognize early signs of mental health conditions and take steps toward getting help. It may be a good fit if you are between 12 and 29, live near certain research sites, and can complete a short screening questionnaire in English.
New York, New YorkAges 12–29 - NCT06774430Recruiting
Digital outreach for young people at risk of psychosis
This study tests a digital program designed to encourage young people to seek help for early signs of psychosis. It aims to see if online messages can increase connections to care.
New York, New YorkAges 12–29 - NCT04007510Enrolling by invitation
Early psychosis study for patients, families, and care teams
This study looks at how to improve early psychosis care using data-driven planning and support for people who are newly developing symptoms. It may help by sharing better ways to coordinate treatment among patients, families, and the clinic/community teams.
Sacramento, CaliforniaAges 8–40 - NCT07196423Recruiting
Early psychosis cognition study
This study explores how thinking and memory work in people who have experienced early psychosis. It involves computer tasks, brain scans, and a type of brain stimulation to better understand cognition. The study has two parts: one for people currently in early psychosis and one for people who have had psychosis at any point.
Nottingham, NottinghamshireAges 18–55 - NCT05365347Recruiting
Program to reduce risky alcohol use in early psychosis
This study tests an intervention aimed at helping people with early psychosis who also drink in a risky way. It may help reduce problematic drinking during a critical early period of illness.
Halifax, Nova ScotiaAges 16–35 - NCT05814913Recruiting
Culturally adapted therapy for early psychosis with caregiver support
This study tests culturally adapted talk-therapy to help people who are in the early stage of psychosis. It also involves a family member or caregiver, which may make the support at home easier and more consistent.
Karachi, SindhAges 18 years+ - NCT05813457Recruiting
Early identification program for first episode psychosis
This study checks whether finding and starting care early for a first episode of psychosis can shorten how long symptoms go untreated. You may be eligible if it’s your first episode and you haven’t been on antipsychotic medicines for long before now.
BronAges 15–35 - NCT07645443Recruiting
Mindfulness group therapy for young adults with early psychosis
This study tests whether a mindfulness-based group therapy program helps young adults who have recently experienced their first psychotic episode. You would participate in group sessions alongside your regular treatment to see if mindfulness can improve how you feel.
Mannheim, Baden-WurttembergAges 16–35 - NCT07231497RecruitingPhase 3
Cognitive training for early psychosis
This study tests whether a medication called modafinil can help improve thinking skills in people who have early psychosis. Participants will also do computer-based cognitive exercises. The goal is to see if combining the medication with training boosts memory, attention, and problem-solving.
Minneapolis, MinnesotaAges 18–35 - NCT06978894Recruiting
Using speech to detect psychosis relapse early
This study tests whether changes in your speech patterns can help predict a psychotic relapse before it happens. If you're in an early psychosis program, you may help develop a tool that could warn you and your care team early.
London, OntarioAges 16 years+ - NCT07616999Recruiting
Long-term follow-up study of early psychosis treatment
This study follows people who were part of an earlier research trial about medication management during their first psychotic episode. Researchers want to understand how those early treatment choices affected their recovery over the past 20 years.
Hong KongAges 18–65 - NCT04004364Recruiting
Research study for people enrolled in a schizophrenia care program
This is an early-stage research study for people who are already enrolled in a specific schizophrenia care program. It aims to improve outcomes by testing practice changes within that program.
Lauderdale Lakes, FloridaAges 15–40
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Common questions
- Are there clinical trials for early psychosis?
- Yes. Clin2 currently lists 22 recruiting early psychosis studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a early psychosis trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a early psychosis trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.