Clinical trials
Psychosis clinical trials
Below are recruiting psychosis clinical trials, each written for real people, not researchers. We’re tracking 147 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07834203Recruiting
State representation in early psychosis study
This study looks at how the brain processes information in people with early psychosis compared to healthy controls. It may help improve understanding and treatment of psychosis.
Minneapolis, MinnesotaAges 15–45 - NCT05814913Recruiting
Culturally adapted therapy for early psychosis with caregiver support
This study tests culturally adapted talk-therapy to help people who are in the early stage of psychosis. It also involves a family member or caregiver, which may make the support at home easier and more consistent.
Karachi, SindhAges 18 years+ - NCT07263022RecruitingPhase 3
Cognitive Training for Early Psychosis Study
This study tests whether a cognitive training program can help young adults with recent psychosis improve their thinking and memory skills. It involves brain scans and cognitive exercises.
Minneapolis, MinnesotaAges 18–35 - NCT07196423Recruiting
Early psychosis cognition study
This study explores how thinking and memory work in people who have experienced early psychosis. It involves computer tasks, brain scans, and a type of brain stimulation to better understand cognition. The study has two parts: one for people currently in early psychosis and one for people who have had psychosis at any point.
Nottingham, NottinghamshireAges 18–55 - NCT07188597Recruiting
Therapy to help prevent first episode of psychosis
This trial tests a culturally adapted talking therapy to help young people who are at risk of having their first episode of psychosis. If you are between 16 and 35, have some early warning signs but no history of psychosis, this study might be a good fit.
Karachi, SindhAges 16–35 - NCT06194344Recruiting
Personalized imagery for sleep and psychosis in inpatients
This study tests whether personalized guided imagery (a relaxation technique) can help improve sleep, reduce psychosis symptoms, and lower suicidal thoughts in people with schizophrenia or mood disorders with psychotic features who are currently in the hospital.
Houston, TexasAges 18 years+ - NCT06778564RecruitingPhase 3
CBD (cannabidiol) for early psychosis
This study tests if adding a CBD medication to your current antipsychotic can improve symptoms in people with schizophrenia or related disorders who started treatment recently but aren't fully better yet.
ViennaAges 16–40 - NCT06740383Recruiting
Study of early psychosis and treatments
This study looks at people who have had psychosis for less than 4 years to understand how their symptoms change over time and how they respond to treatment. By using brain scans and other tests, researchers hope to find better ways to personalize care for early psychosis.
Hartford, ConnecticutAges 18–40 - NCT05731414Recruiting
Testing behavior programs to improve outcomes in schizophrenia
This study looks at how a behavioral program (including remediation and behavior-based techniques) may improve outcomes for adults with schizophrenia-spectrum conditions. You may be eligible if you meet basic age/language needs and haven’t done certain therapies recently.
Scarborough Village, OntarioAges 18–65 - NCT06640803Recruiting
Early psychosis risk stepped-care program
This study offers a step-by-step care program for teens and young adults at high risk for psychosis. It aims to provide the right level of support early on to prevent or reduce the severity of symptoms.
Elk Grove, CaliforniaAges 12–25 - NCT06071858Recruiting
Enhanced coordinated care for early psychosis
This trial studies an enhanced version of coordinated specialty care (CSC) for people experiencing their first episode of psychosis. It aims to improve outcomes by providing more intensive support and coordination among different healthcare providers.
Belmont, MassachusettsAges Any age - NCT05509998Recruiting
Improving early care for untreated psychosis
This trial looks at ways to help people get treatment sooner after psychosis starts. It focuses on how screening and better communication across care teams may reduce the time before treatment begins.
New York, New YorkAges 12–30 - NCT04368039Recruiting
Breathing regular air pressure oxygen for first-time psychosis
This trial tests whether breathing oxygen (not high-pressure) can improve symptoms in people experiencing a first episode of psychosis. It may help reduce symptoms by changing oxygen delivery to the brain early in the illness.
Columbus, OhioAges 15–35 - NCT03971487RecruitingPhase 1/Phase 2
Ocrelizumab for psychosis linked to an overactive immune system
This Phase 1/2 study tests ocrelizumab, a medicine that affects parts of the immune system, to see if it can improve psychosis symptoms in people with schizophrenia-spectrum disorders. It’s mainly for younger adults with ongoing psychosis and evidence that the symptoms began early in life, with certain infection/vaccine safety requirements.
Houston, TexasAges 18–35 - NCT05858255Recruiting
Exergaming program for people with psychosis
This study tests whether an “exergaming” exercise program (video games that make you move) can help people with schizophrenia-spectrum conditions. It’s meant to see if this kind of guided activity is safe and beneficial for symptoms and wellbeing.
Tønsberg, VestfoldAges 18–65 - NCT07786714Recruiting
Faster brain stimulation for early psychosis risk
This study tests a faster type of brain stimulation, called accelerated neuromodulation therapy, in people who have early signs that could lead to psychosis. The goal is to see if this treatment can help reduce symptoms and improve daily life.
Verdun, QuebecAges 18–34 - NCT05365347Recruiting
Program to reduce risky alcohol use in early psychosis
This study tests an intervention aimed at helping people with early psychosis who also drink in a risky way. It may help reduce problematic drinking during a critical early period of illness.
Halifax, Nova ScotiaAges 16–35 - NCT07747181Recruiting
Brain stimulation and yoga for thinking skills in psychosis
This study tests whether combining brain stimulation with yoga can improve thinking and memory in people with psychosis. It may help with daily functioning and quality of life.
Hung Hom, KowloonAges 18–65 - NCT07749105Recruiting
Cognitive strategies for first-episode psychosis to improve work and school
This study tests a cognitive self-management program to help young people with first-episode psychosis improve their thinking skills and achieve work or school goals. It may help you get back to school or work.
Big Spring, TexasAges 15–32 - NCT07716969Recruiting
Reducing time without treatment for psychosis
This trial tests a program to help people get treatment faster for psychosis. It is for patients who have started OPUS treatment within the last 9 months and may have a schizophrenia-related condition.
Copenhagen, DenmarkAges 18–35 - NCT06634446Recruiting
Self-guided cognitive training for early psychosis
This study tests a self-guided cognitive training program designed for young people who recently had their first episode of psychosis. It aims to improve thinking skills and daily function through exercises you can do at home.
ParisAges 16–35 - NCT06650943Recruiting
Nursing help for weight and metabolic health in early psychosis
This study tests a nursing program to help people with early psychosis manage weight and reduce the risk of metabolic syndrome (a cluster of conditions that raise heart disease risk). It's designed for people who have had their first psychotic episode within the last 5 years.
Bilbao, VizcayaAges Any age - NCT05457140Recruiting
Testing genes and other samples in youth with first psychosis
This study looks at many types of tests (including genetic testing and other lab data) to help understand what may be causing first-time psychosis symptoms in youth. It may help doctors learn more about the condition for future care, and it can involve analyzing family genetic information.
San Diego, CaliforniaAges 7–17 - NCT04789915RecruitingPhase 1
Testing memantine added to dopamine-targeting treatment for early psychosis
This Phase 1 study tests whether adding memantine can improve “negative symptoms” (like low motivation, reduced emotional expression) in people having their first episode of psychosis. It’s designed to understand safety and early effects when dopamine-related treatment is adjusted.
Glostrup Municipality, Capitol RegionAges 18–45
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Psychosis trials by city
Studies with a site in or near these metro areas.
Psychosis trials by state
Studies with a site anywhere in these states.
Common questions
- Are there clinical trials for psychosis?
- Yes. Clin2 currently lists 147 recruiting psychosis studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a psychosis trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a psychosis trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.