Clinical trials
Edentulism clinical trials
Below are recruiting edentulism clinical trials, each written for real people, not researchers. We’re tracking 70 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06723678Recruiting
Bone changes around implants with All-on-Four technique
This trial tests a special technique called 'All-on-Four' for people who need full-arch dental implants. It looks at how the bone around the implants changes over time. If you are in good general health and have a healthy jawbone, this study might help you understand if this approach works well for you.
Cairo, Nasr CityAges 50–65 - NCT06721377Recruiting
Comparing denture attachments for implant-supported lower dentures
This trial tests different ways to attach a lower denture to dental implants. It aims to find which attachment type works best for people who need a stable, comfortable denture.
Cairo, Nasr City - CairoAges 65–69 - NCT07693946Recruiting
Jaw tracking for better implant fitting in the upper jaw
This study tests if using a special jaw tracker helps make upper-jaw implants fit better and feel more natural when you have your own lower teeth. The goal is to see if it improves your bite and overall comfort.
Al Mansurah, Dakahlia GovernorateAges 50–70 - NCT04766255RecruitingPhase 4
Comparing materials to thicken gum tissue around dental implants
This study compares three types of graft (tissue/covering materials) to help build up thicker gum and soft tissue around a dental implant. It may help improve appearance and protect the implant area when you have thin or missing gum tissue.
Sant Cugat del Vallès, BarcelonaAges 18 years+ - NCT06593925Recruiting
Snap-on denture made from a strong plastic for older adults
This trial tests a new plastic material (polyoxymethylene) to make a telescopic denture—a partial denture that snaps onto your remaining teeth. It is for people aged 65 and older who have lost several teeth but still have some healthy teeth to support the denture.
BelgradeAges 65–100 - NCT07723404Recruiting
Comparing two ways to scan dental implants for a new bridge
This trial compares two techniques for scanning dental implants in the upper jaw to make a new permanent bridge or denture. It aims to find which method gives a more accurate fit.
Shibīn al Kawm, Shibin AlkomAges 20–60 - NCT07104370Recruiting
Comparing freeze-dried donor bone vs. your own bone for jaw grafting
This trial compares two types of bone graft materials for rebuilding the jawbone so you can later get dental implants. One is a freeze-dried bone from a donor (allograft), and the other is a small piece of your own bone (autograft).
Budapest, HungaryAges 18 years+ - NCT06080633Recruiting
Facial prediction tech for people with no teeth
This study tests a new facial prediction technology that helps create better-fitting dentures for people with no natural teeth. It may improve how your dentures look and feel.
Leuven, HeverleeAges 50–100 - NCT06149585Recruiting
Bacteria changes in gum disease patients getting all dental implants
This study looks at how bacteria in your mouth change when all your teeth are removed and replaced with dental implants. If you have severe gum disease and need all your teeth extracted, joining this trial could help researchers understand your healing process.
Cleveland, OhioAges 21 years+ - NCT06773923Enrolling by invitationPhase 3
3D-printed bone scaffold trial for dental implants
This trial tests a 3D-printed scaffold that dissolves over time to help regrow jawbone for dental implants. It is for people in Valdivia, Chile, who need bone buildup in the lower jaw.
ValdiviaAges 30–70 - NCT07778199Recruiting
Implant denture fitting: digital vs traditional dental impressions
This trial compares two ways of taking dental impressions (molds) for making a full-arch implant-supported denture. One method uses a digital scanner, the other uses traditional dental putty. The goal is to see if one results in a more comfortable and precise fit.
Al Mansurah, Dakahlia GovernorateAges 35–70 - NCT07541625Recruiting
Digital scanning for custom tooth attachments
This research tests whether advanced scanning technology improves the fit of custom attachments placed inside root-canal-treated teeth to support dentures. If you have some remaining teeth that need support and are considering a denture, this trial may help you get a better-fitting solution.
Giza, الجيزةAges 18–65 - NCT06643975Recruiting
Comparing tooth implants for lower jaw overdentures
This study compares patient satisfaction and bone changes around two types of dental implants used to support a removable lower denture. It may help you understand which implant material works best for you.
CairoAges 50–60 - NCT06273449Recruiting
Smart digital workflow for partial dentures
This trial tests a new, computer-assisted method for making partial dentures that fit more precisely. You may be eligible if you already have experience wearing a partial denture and are missing some teeth.
SingaporeAges 21 years+ - NCT06012071Recruiting
Zirconia implants for a missing upper premolar
This trial tests two types of zirconia (ceramic) dental implants for replacing a single missing upper premolar. It aims to see which implant platform works best for long-term stability.
LjubljanaAges 25 years+ - NCT04927819Recruiting
Extra-short versus standard dental implants in a fixed bridge
This study compares extra-short dental implants versus standard-length implants when they are joined together in the same fixed bridge. It may help people understand which implant type works better for supporting a stable multi-tooth replacement.
Vitoria-GasteizAges 18 years+ - NCT04276246Recruiting
Dental implant supports for removable dentures in back-tooth gaps
This trial tests whether small “supporting” implants can help hold a removable partial denture more securely. It’s for adults missing back teeth on both sides (a specific dental gap pattern) and may improve comfort and fit.
BaselAges 18 years+ - NCT07657364Recruiting
Comparing zirconia vs titanium for full-arch dental implants
This study compares two types of material (zirconia or titanium) used as a frame in full-arch screw-retained implant bridges. It aims to find which material has fewer complications, helps patients who have lost all teeth in one or both jaws.
CairoAges 18–70 - NCT06388395Enrolling by invitation
Comparison of PEEK and Conventional Dental Prostheses
This study compares two types of full-arch dental prostheses (PEEK and conventional) placed on four implants in the lower jaw, to see which works better. It may be an option if you need all lower teeth replaced and have healthy jawbone.
Sharjah cityAges 18 years+ - NCT06221306Recruiting
Comparing narrow vs standard dental implants for jaw bone loss
This trial tests whether narrow dental implants can preserve jaw bone better than standard implants with bone grafting in people missing back teeth. If you have a narrow jawbone, this study may help determine which option works best for you.
Cairo, Greater CairoAges 18 years+ - NCT07034079RecruitingPhase 2
Adding ridges to dentures for better fit and comfort
This study tests adding small ridges (called palatal rugae) to a complete upper denture to see if it makes patients more satisfied and improves their quality of life related to oral health. It may help dentures feel more natural and stable.
Islamabad, IslamabadAges 40–80 - NCT07523815RecruitingPhase 4
AI-Assisted versus Standard Planning for Dental Implants
This study compares using artificial intelligence computer planning versus standard planning methods for placing a single dental implant in your back teeth. The goal is to see if AI planning makes the implant placement faster, easier, and more precise.
Cairo, ManialAges 18–50 - NCT06688669Recruiting
Removable denture study for adults over 60
This study looks at how removable dentures affect daily life in people over 60. You may join if you need new dentures for both upper and lower jaws and are otherwise healthy enough for the procedure.
Istanbul, VeznecilerAges 60 years+ - NCT06018701RecruitingEarly Phase 1
Dental device secured with bone cement for missing teeth
This trial tests a special dental device that is cemented into the jawbone for people missing one or more teeth. It may be a good option if your jawbone is dense enough and you don't have serious other health issues.
Kathmandu, BagmatiAges 18–80
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Common questions
- Are there clinical trials for edentulism?
- Yes. Clin2 currently lists 70 recruiting edentulism studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a edentulism trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a edentulism trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.