Clinical trials
Fibroid clinical trials
Below are recruiting fibroid clinical trials, each written for real people, not researchers. We’re tracking 31 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07012161RecruitingEarly Phase 1
Vitamin D for fibroid symptoms in women with low vitamin D
This trial tests whether taking vitamin D3 can help reduce symptoms like heavy bleeding or pressure from uterine fibroids. It is for women who have fibroids and are also low in vitamin D.
Dhaka, SahabagAges 18–50 - NCT07402369RecruitingPhase 2
Testing CMS-D002 for heavy bleeding from uterine fibroids
This trial tests a capsule called CMS-D002 for heavy periods caused by uterine fibroids. It might help reduce your bleeding if you have fibroids at least 2 cm in size, regular cycles, and are between 18 and 50.
Beijing, Beijing MunicipalityAges 18–50 - NCT06143631RecruitingPhase 4
Letrozole study for uterine fibroids
This trial tests if the drug letrozole can improve symptoms like heavy bleeding and pelvic pain caused by uterine fibroids. You must be premenopausal with moderate to severe symptoms and not have very large fibroids or certain other conditions.
Los Angeles, CaliforniaAges 21–53 - NCT05386615Recruiting
Pregnancy follow-up registry after Exablate for fibroids
This study keeps track of people’s pregnancy and birth outcomes after having Exablate treatment for symptomatic uterine fibroids. It may help doctors understand how safe and effective the treatment can be for future pregnancy plans.
Los Angeles, CaliforniaAges 18–50 - NCT05448365Recruiting
Vitamins and plant compounds for uterine fibroid symptoms
This trial studies whether a combination of vitamin D, epigallocatechin gallate (a plant compound), D-chiro-inositol, and vitamin B6 can improve symptoms from uterine fibroids. It may help by reducing symptoms such as heavy or irregular bleeding and pelvic pain in people who can undergo surgery.
Francavilla Fontana, ApuliaAges 30–40 - NCT05862272RecruitingPhase 3
Testing long-term bone density support in fibroids or endometriosis
This study tests how well a long-term treatment using a relugolix combination tablet helps protect bone density in women who have uterine fibroids or endometriosis. It may help people who are at risk of bone thinning while receiving hormone-related symptom treatment.
Mobile, AlabamaAges 18–50 - NCT06135870Recruiting
Study of senescent cells in uterine fibroids
This study looks at how aging cells in the uterus may cause fibroids. Researchers will collect tissue and blood samples to understand fibroid growth better.
Baltimore, MarylandAges 18–55 - NCT06671548RecruitingPhase 3
Study of relugolix for heavy periods from uterine fibroids
This trial tests if relugolix can reduce heavy menstrual bleeding caused by uterine fibroids. It may be an option for women who want to avoid surgery.
BeijingAges 18 years+ - NCT06692335Recruiting
Comparing HIFU and surgery for uterine fibroids
This trial compares two treatments for painful or heavy menstrual bleeding caused by uterine fibroids: high-intensity focused ultrasound (HIFU) and myomectomy (surgery to remove fibroids). It may help you decide which option fits your needs.
Hong KongAges 18–50 - NCT06705075RecruitingPhase 2
Contrast ultrasound for uterine fibroids before and after UAE
This trial uses special contrast-enhanced ultrasound (CEUS and SHAPE) to take detailed images of uterine fibroids before and after a procedure called uterine artery embolization (UAE). It aims to help doctors better understand how fibroids respond to treatment.
Philadelphia, PennsylvaniaAges 18 years+ - NCT07072364Recruiting
Videos to help decide on fibroid treatment
This study tests if watching short videos helps people with uterine fibroids make better treatment decisions with their doctor. You are eligible if you have fibroids and are scheduled to discuss options at a Penn Medicine clinic.
Philadelphia, PennsylvaniaAges 18–55 - NCT07078682Recruiting
Study of two supplements for uterine fibroid symptoms
This trial tests two supplements (Elix Cycle Balance and Elix Daily Harmony) to see if they can reduce pain and other symptoms caused by uterine fibroids. It is for women who have regular but painful periods and want to try a non-medicine option.
Las Vegas, NevadaAges 20–45 - NCT07173127Recruiting
Ryeqo for fibroids and endometriosis: blood clotting study
This study looks at how Ryeqo, a medicine for uterine fibroids and endometriosis, affects blood clotting in women taking it. It aims to make sure the treatment is safe for your body's clotting system.
Geneva, Canton of GenevaAges 18 years+ - NCT07378098RecruitingPhase 3
Study of KLH-2109 for uterine fibroids with heavy bleeding
This trial tests a new medicine called KLH-2109 for women who have uterine fibroids that cause heavy menstrual bleeding. The goal is to see if the medicine can reduce bleeding and improve symptoms.
SeoulAges 19 years+ - NCT07647198RecruitingPhase 2
Green tea extract and vitamin D to prevent fibroid return
This study tests whether two natural supplements—green tea extract (EGCG) and vitamin D—can help prevent uterine fibroids from coming back after treatment. You would take these supplements for 12 months while avoiding pregnancy.
Abu Dhabi, United Arab Emirates (uae)Ages 18 years+ - NCT07129005Enrolling by invitation
MRI-based tool to tell uterine sarcoma from fibroids
This trial uses MRI scans to see if a computer can tell the difference between uterine sarcoma (a rare cancer) and fibroids (non-cancerous growths). If you've already been diagnosed with one of these and had an MRI before surgery, you may be able to help.
Wuhan, HubeiAges 18 years+ - NCT06435663Recruiting
ultramicro-flow technique for focused ultrasound treatment of uterine tumors
This study tests a new imaging tool (ultramicro-flow technique) to help doctors treat uterine fibroids or adenomyosis with focused ultrasound without surgery. The goal is to make the treatment safer and more accurate, especially for tumors deep inside the uterus.
Yiwu, ZhejiangAges 18–50 - NCT07740759Enrolling by invitation
Educational videos for pre-surgery anxiety
This trial tests whether watching educational videos before your laparoscopic surgery helps reduce anxiety. It may help you feel more prepared and calm before your procedure.
Farmington, ConnecticutAges 18 years+ - NCT05979493RecruitingPhase 4
Nerve block for pain after fibroid surgery
This study tests whether a nerve block (QL block) can help with pain after surgery to remove uterine fibroids while keeping the uterus. It may be a good option if you are having a laparoscopic myomectomy and want to manage pain without strong opioids.
Beachwood, OhioAges 18–45 - NCT06153667Recruiting
Bearing nsPVA for uterine fibroid embolization (UAE)
This trial tests a new particle material, Bearing nsPVA, for uterine artery embolization (UAE), a procedure that blocks blood flow to fibroids to shrink them and reduce symptoms like heavy bleeding or pain. It aims to see if this material is safe and effective for women with symptomatic fibroids.
Brooklyn, New YorkAges 18 years+ - NCT06269809Recruiting
Temporary Artery Clipping for Robotic Myomectomy
This trial tests if temporarily clipping arteries during robotic surgery for uterine fibroids (non-cancerous growths) reduces blood loss and makes the surgery safer. It may help women who need fibroid removal and are candidates for robotic surgery.
LeuvenAges 18 years+ - NCT06392997Recruiting
Saliva test for gynecologic conditions before surgery
This study is testing a simple saliva sample to see if it can help detect gynecologic conditions (like endometriosis, fibroids, or ovarian/uterine/cervical cancer) before or during surgery. If you are having surgery or a biopsy for one of these issues, your saliva may help improve diagnosis.
AngersAges 18 years+ - NCT06536517RecruitingPhase 2
Methadone during hysterectomy to reduce pain pills
This study tests whether a single dose of methadone given during minimally invasive hysterectomy (for non-cancer reasons) can reduce the need for opioid pain pills after surgery. It aims to see if this approach helps with pain control and lessens opioid use.
Baltimore, MarylandAges 18 years+ - NCT06845982Recruiting
New biopsy method for uterine fibroids
This trial tests a new ultrasound-guided biopsy technique through the vagina to get tissue samples from uterine fibroids or smooth muscle tumors. It aims to see if this method is safer and more accurate than standard approaches.
MarseilleAges 18 years+
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Common questions
- Are there clinical trials for fibroid?
- Yes. Clin2 currently lists 31 recruiting fibroid studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a fibroid trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a fibroid trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.