Clinical trials · California
Glaucoma clinical trials in California
We’re tracking 25 recruiting glaucoma studies with a site in California — including Phase 1, Phase 2 and Phase 3 studies, each written for real people, not researchers.
Recruiting studies in California
- NCT06822738RecruitingPhase 3
Study of XEN63 gel stent for glaucoma patients
This trial tests a new gel stent (XEN63) to lower eye pressure in adults with glaucoma. It compares two ways of putting the stent in the eye, and may help people who have not had success with other treatments.
Culver City, CaliforniaAges 45 years+ - NCT06685211Recruiting
Electrical stimulation for vision in glaucoma
This trial tests whether gentle electrical stimulation can help improve vision in people with moderate vision loss from glaucoma. It might offer a new way to strengthen remaining vision.
Palo Alto, CaliforniaAges 18 years+ - NCT06854198Recruiting
Glaucoma screening for at-risk Californians
This study tests whether offering eye exams at a health center helps find glaucoma early in people who are at higher risk. It may help you catch vision problems before they get worse.
Oakland, CaliforniaAges 50 years+ - NCT07220876Recruiting
VisiPlate implant for hard-to-control open-angle glaucoma
This trial tests a new device called VisiPlate that is placed in the eye to help lower pressure for people with hard-to-control open-angle glaucoma. It may be an option if standard treatments haven't worked well enough.
Sacramento, CaliforniaAges 45 years+ - NCT06693882Enrolling by invitation
Electrical stimulation for glaucoma
This study tests if mild electrical stimulation of the optic nerve can help people with moderate to advanced glaucoma. It may be an option if your glaucoma has gotten worse despite standard treatments.
San Francisco, CaliforniaAges 18 years+ - NCT07520175Enrolling by invitation
Bio-Reinforced Canaloplasty for Open-Angle Glaucoma
This study tests a newer surgical procedure called bio-reinforced canaloplasty, which helps fluid drain better from the eye to lower eye pressure in people with open-angle glaucoma. Researchers will follow patients to see how well this procedure works and how safe it is.
Chico, CaliforniaAges Any age - NCT04354545Recruiting
Testing treatments for eye discomfort in glaucoma
This trial studies how to treat eye surface discomfort in people who have glaucoma and are already using multiple eye drops. It may help reduce symptoms like irritation while keeping glaucoma treatment on track.
Fountain Valley, CaliforniaAges Any age - NCT05206877RecruitingPhase 1
Topical insulin eyedrops for glaucoma-related eye nerve damage
This Phase 1 study tests an insulin-based eye treatment to see if it’s safe and potentially helpful for people with glaucoma-related optic nerve damage. If you may be eligible, you’ll have a close eye exam and repeated vision testing, mainly focused on one study eye.
Palo Alto, CaliforniaAges 18 years+ - NCT05401357RecruitingPhase 3
Test eye drops for glaucoma or high eye pressure in both eyes
This Phase 3 study compares two versions of the same glaucoma eye-drop medicine (bimatoprost 0.01%) to see how similarly they work and their effect on eye pressure. It may help people with chronic open-angle glaucoma or ocular hypertension who need treatment in both eyes.
Petaluma, CaliforniaAges 18 years+ - NCT05626426Recruiting
Electrical stimulation for optic nerve damage from glaucoma
This trial studies whether electrical stimulation can help improve vision in people with glaucoma-related optic nerve damage. You may qualify if your visual field test shows moderate to severe loss and your eye pressure is stable.
Palo Alto, CaliforniaAges 18 years+ - NCT05924477Recruiting
Compare glaucoma shunt options to prevent cell loss
This study compares a glaucoma drainage device approach to see which one better prevents loss of corneal cells after surgery. You may benefit by receiving close monitoring around the time of glaucoma surgery and helping doctors improve surgical choices.
San Francisco, CaliforniaAges 18 years+ - NCT06223048RecruitingPhase 2
Study of AMDX-2011P for primary open angle glaucoma
This trial tests an investigational drug called AMDX-2011P for people with primary open angle glaucoma in both eyes. It aims to see if the drug can help protect the optic nerve and preserve vision.
Glendale, CaliforniaAges 22 years+ - NCT06267274RecruitingPhase 1
Comparing two forms of bimatoprost for glaucoma or high eye pressure
This trial tests whether a new formulation of bimatoprost works as well as an existing one to lower eye pressure in people with chronic open-angle glaucoma or ocular hypertension. It involves multiple eye drop doses and checks for safety and effectiveness.
Bakersfield, CaliforniaAges 18 years+ - NCT07354477RecruitingPhase 2
New eye drop for glaucoma and diabetic retinopathy
This trial tests a new eye drop (QLS-111) to see if it improves blood flow in the back of the eye. It may help people with mild to moderate glaucoma or stable diabetic retinopathy by reducing pressure inside the eye and nourishing the optic nerve.
Palo Alto, CaliforniaAges 18 years+ - NCT07290244RecruitingPhase 1
Testing ER-100 safety for glaucoma or NAION patients
This trial tests whether a new drug, ER-100, is safe for people with glaucoma or a sudden optic nerve injury called NAION. It aims to see if the drug can be given without serious side effects.
Glendale, CaliforniaAges 40–85 - NCT00221897Recruiting
Eye test study to help diagnose glaucoma
This study tests new ways to evaluate eyes to help diagnose glaucoma and related eye conditions. You may be able to join if you’re an adult with normal eye health or with concerns like myopia, glaucoma suspicion, or ocular hypertension.
La Jolla, CaliforniaAges 18 years+ - NCT07327242Enrolling by invitation
AI tool to improve eye test accuracy in glaucoma patients
This trial tests if a large language model tool can help patients perform more reliable visual field tests. It may improve detection of glaucoma progression.
Palo Alto, CaliforniaAges 18 years+ - NCT03752840Recruiting
Community eye-worker program in Nepal
This trial tests a village-based approach to bring eye care closer to older community members. If you live in the right area and are willing to participate, it may help improve access to eye screening and services.
San Francisco, CaliforniaAges 60 years+ - NCT04553523Recruiting
Hydrus microstent study for open-angle glaucoma with cataracts
This study enrolls people who have cataracts and primary open-angle glaucoma that is being treated with eye drops. It will look at how well the Hydrus microstent works after approval, especially for lowering eye pressure safely.
Irvine, CaliforniaAges 45 years+ - NCT04967989RecruitingPhase 3
Laser eye treatment timing for certain glaucoma or eye pressure
This Phase 3 study tests how best to use a laser treatment (SLT) for people with high eye pressure or mild-to-moderate primary open-angle glaucoma. It aims to find the best way to lower eye pressure and protect vision while comparing treatment approaches.
Pasadena, CaliforniaAges 18 years+ - NCT06128720Recruiting
Hyperbaric oxygen therapy for optic nerve damage
This study tests if breathing pure oxygen in a pressurized chamber (hyperbaric oxygen therapy) can help people with optic neuropathy, a condition that damages the nerve connecting the eye to the brain.
Palo Alto, CaliforniaAges 18 years+ - NCT06943599Recruiting
Improving Eye Care After Screening
This study looks at better ways to help people get follow-up eye care after a screening. If you were in the VIEW II study and were referred to an eye hospital, this trial may offer strategies to support you in getting that care.
San Francisco, CaliforniaAges 60 years+ - NCT07149740Recruiting
A study to collect images of eyes for new camera technology
This trial uses a special camera (OCT) to capture detailed images of the eye. It aims to improve eye disease detection. You may join if you have retinal disease, glaucoma, corneal disease, or healthy eyes.
Anaheim, CaliforniaAges 22 years+ - NCT07661329RecruitingPhase 3
Comparing a new eye drop to a standard one for glaucoma and high eye pressure
This study tests a new eye drop against an existing one to see which better lowers eye pressure in people with open-angle glaucoma or ocular hypertension. You may be able to join if you have high eye pressure in both eyes that needs treatment and you are at least 18 years old.
Petaluma, CaliforniaAges 18 years+
Glaucoma trials by city in California
Where these studies are running in California
Institutions with a site for the recruiting glaucoma studies listed above.
- Byers Eye Institute at Stanford University · 5 studies
- University of California, San Francisco · 5 studies
- Eye Research Foundation · 4 studies
- North Bay Eye Associates · 4 studies
- Doheny Eye Center UCLA · 2 studies
- Global Research Management, Inc. · 2 studies
- Sacramento Eye Consultants · 2 studies
- Baywell Health
What taking part in a glaucoma study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Glaucoma trials in other states
Common questions
- Are there glaucoma clinical trials in California?
- Yes. We're currently tracking 25 recruiting glaucoma studies with a site in California, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a glaucoma study in California?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in California to take part?
- Not necessarily. These studies have a site in California, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a glaucoma trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New glaucoma studies open in California regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.