Clinical trials · Minnesota
Glioma, Malignant clinical trials in Minnesota
We’re tracking 7 recruiting glioma, malignant studies with a site in Minnesota — including Early Phase 1, Phase 1 and Phase 1/Phase 2 studies, each written for real people, not researchers.
Recruiting studies in Minnesota
- NCT05717153RecruitingEarly Phase 1
Test drugs through the tumor to study brain tumor metabolism
This early-phase study tests two drugs (DFMO and AMXT 1501) given directly into the tumor to see how they affect tumor biology and metabolism. Researchers may learn whether this approach could be safer and helpful for people with diffuse or high-grade glioma.
Rochester, MinnesotaAges 18 years+ - NCT05099003RecruitingPhase 1/Phase 2
Selinexor plus radiation for newly diagnosed brain tumors
This trial studies whether adding selinexor to standard radiation can improve outcomes for children and young teens with certain newly diagnosed high-grade brain tumors (including DIPG). It’s designed for specific tumor types and genetic markers, and people must be able to start treatment soon after diagnosis.
Minneapolis, MinnesotaAges 1–21 - NCT06810544RecruitingPhase 1/Phase 2
Study of TNG456 for tumors with MTAP loss
This trial tests a new drug called TNG456, alone or with another drug (abemaciclib), for people whose tumors have lost the MTAP gene. It aims to see if the combination can shrink tumors or slow their growth.
Rochester, MinnesotaAges 18 years+ - NCT07468136RecruitingPhase 1/Phase 2
Retifanlimab with or without DFMO for progressive high-grade gliomas
This study tests a combination of two drugs—retifanlimab (an immunotherapy that helps your immune system fight cancer) and DFMO (a medicine that may stop tumor growth)—in people with high-grade brain tumors that are growing. Participants will receive these treatments before and after their planned surgery.
Rochester, MinnesotaAges 18 years+ - NCT04870944RecruitingPhase 1/Phase 2
CBL0137 for children with advanced solid or brain tumors
This early-phase study tests CBL0137 in children and teens whose cancer has come back or is not responding to treatment. It is also for some specific hard-to-treat brain tumors, to see if the drug is safe and can work against the cancer.
Minneapolis, MinnesotaAges 1–21 - NCT04047264Recruiting
Monitoring brain chemistry during brain surgery
This study tests whether a tiny probe can safely measure brain chemistry during and after brain surgery. It may help doctors better understand and treat brain conditions like tumors or epilepsy.
Rochester, MinnesotaAges 18 years+ - NCT05538130RecruitingPhase 1
Study medicine for BRAF-mutated advanced solid tumors
This Phase 1 trial studies how PF-07799544 works and what dose is safest in people with advanced cancer that has a specific genetic change called BRAF V600. You may receive it alone or with another treatment, depending on the tumor group, to see if it can treat the cancer.
Saint Louis Park, MinnesotaAges 16 years+
Where these studies are running in Minnesota
Institutions with a site for the recruiting glioma, malignant studies listed above.
- Mayo Clinic · 4 studies
- University of Minnesota Masonic Cancer Center · 2 studies
- Children's Hospitals and Clinics of Minnesota - Minneapolis
- HealthPartners Frauenshuh Cancer Center
- Methodist Hospital Inpatient Pharmacy
- Regions Hospital
What taking part in a glioma, malignant study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Glioma, Malignant trials in other states
Common questions
- Are there glioma, malignant clinical trials in Minnesota?
- Yes. We're currently tracking 7 recruiting glioma, malignant studies with a site in Minnesota, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a glioma, malignant study in Minnesota?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Minnesota to take part?
- Not necessarily. These studies have a site in Minnesota, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a glioma, malignant trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New glioma, malignant studies open in Minnesota regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.