Test drugs through the tumor to study brain tumor metabolism
Treatments studied
Part of Cancer clinical trials.
This early-phase study tests two drugs (DFMO and AMXT 1501) given directly into the tumor to see how they affect tumor biology and metabolism. Researchers may learn whether this approach could be safer and helpful for people with diffuse or high-grade glioma.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older
- You have a diffuse or high-grade brain tumor diagnosis based on scan and/or past diagnosis
- Your neurosurgeon plans a biopsy or partial removal because of where the tumor is
- You can stay in the hospital at Mayo Clinic for extra days for monitoring and sampling
- Your blood counts and liver/kidney tests are in acceptable ranges, and you can have MRI scans
- You can take oral study medicine (swallow tablets) and you do not have a drug allergy to DFMO or AMXT 1501
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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