Clinical trials
Hemorrhoids clinical trials
Below are recruiting hemorrhoids clinical trials, each written for real people, not researchers. We’re tracking 33 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07635784Recruiting
Hemorrhoid Treatment Registry: Tracking Embolization Safety
This registry collects information about a minimally invasive procedure called hemorrhoidal artery embolization (HAE), which blocks blood vessels feeding internal hemorrhoids. It's for adults with persistent bleeding hemorrhoids that haven't improved with standard treatments like creams or medications.
Libertyville, IllinoisAges 18 years+ - NCT07333040Recruiting
Energy therapy vs. surgery for grade III hemorrhoids
This trial compares two less invasive energy-based treatments with standard surgery for people with grade III hemorrhoids. If you are between 18 and 75 and your hemorrhoids cause significant symptoms, this study may help find a gentler option.
TaoyuanAges 18–75 - NCT07295886Recruiting
Cream for Protruding Hemorrhoids
This trial tests a cream containing two medicines (nifedipine and lidocaine) for painful, protruding hemorrhoids. The cream may help reduce pain and swelling. You can join if you have moderate to severe hemorrhoids that come out of the anus and have already started the cream in the last five days.
NaplesAges 18–75 - NCT07559630Recruiting
Artery Blocking vs Rubber Bands for Internal Hemorrhoids
This trial compares two treatment methods for internal hemorrhoids that haven't improved with diet, fiber, or creams. One method blocks blood flow to the hemorrhoids using a catheter (a thin tube); the other uses rubber bands to cut off blood supply. Both are minimally invasive procedures.
Los Angeles, CaliforniaAges 18–89 - NCT07179601Recruiting
Embolization for hemorrhoid symptoms study
This trial tests if blocking certain blood vessels in the rectum can reduce bleeding and other symptoms from hemorrhoids. If you have bothersome internal hemorrhoids that haven't been helped by other treatments or if surgery is not an option for you, this study may be a fit.
Los Angeles, CaliforniaAges 18–90 - NCT05697562Recruiting
Embolization treatment for hemorrhoid bleeding
This trial studies a procedure that blocks blood flow to bleeding hemorrhoids (called superior rectal arterial embolization). It may help people with hemorrhoid bleeding who are being considered for treatment, especially when bleeding is significant.
JetteAges 18 years+ - NCT05782010Recruiting
Testing a hemorrhoid device for grade II or III hemorrhoids
This study tests how safe and well a hemorrhoid treatment device (PexyEazy®) works for adults with moderate-to-severe hemorrhoids (grade II–III). You may be a candidate if you fit the hemorrhoid grade and medical safety requirements and can follow the study plan.
FrölundaAges 18–84 - NCT06625138Recruiting
Latex vs non-latex banding for hemorrhoids
This study compares two types of rubber bands (one made of latex, one not) used to treat internal hemorrhoids. It may help find the better option for people with grade 2-3 hemorrhoids.
Pasadena, CaliforniaAges 18 years+ - NCT06878209Recruiting
Cough and hemorrhoids study
This study looks at how coughing may relate to hemorrhoids. Researchers want to understand the possible connection in people who have hemorrhoids but haven't had surgery for them.
Muğla, MenteşeAges 18 years+ - NCT06535269Recruiting
Pain after hemorrhoid surgery: standard vs bipolar sealer
This study compares two ways of removing hemorrhoids during surgery: one uses a standard electric tool, the other uses a special device (Caiman®) that seals blood vessels. It aims to see which method causes less pain after the operation.
Sabadell, BarcelonaAges 18–65 - NCT07520734Recruiting
Laser Treatment for Internal Hemorrhoids: Treatment Outcomes
This study tracks how well laser treatment works for people with symptomatic internal hemorrhoids (swollen blood vessels in the lower rectum that cause bleeding, itching, or pain). You would undergo the laser procedure and be followed to see how your symptoms improve.
Sanliurfa, ŞanlıurfaAges 18 years+ - NCT07161765Enrolling by invitation
Straining and bowel issues in bleeding hemorrhoids
This study looks at how problems with bowel movements and straining relate to bleeding hemorrhoids. It may help find better ways to treat these symptoms.
Ann Arbor, MichiganAges 18 years+ - NCT04169152Recruiting
Treatment for internal hemorrhoids and rectal prolapse
This trial studies a procedure (“CAES”) for people with internal hemorrhoids (grades I–III) and/or rectal prolapse. It may help reduce symptoms and improve bleeding or discomfort, as long as your condition fits the study’s safety rules.
Nanjing, JiangsuAges Any age - NCT04896268Recruiting
Radiofrequency vs Doppler-guided surgery for hemorrhoids
This study compares two treatment approaches for hemorrhoids that are grades II–III and did not improve with non-surgical treatments. It looks at safety and whether the treatments work better for symptom relief.
Saint-DoulchardAges 18–75 - NCT06106269Recruiting
Outcomes of rectal artery embolization for bleeding hemorrhoids
This study looks at how well rectal artery embolization (a procedure that uses tiny particles to block blood flow to hemorrhoids) works for treating bleeding internal hemorrhoids. It aims to understand if this treatment improves quality of life and reduces symptoms.
Rochester, MinnesotaAges 18–90 - NCT07128979RecruitingPhase 4
Studying butcher’s broom for moderate hemorrhoids
This study tests a plant-based medication made from butcher’s broom (Ruscus aculeatus) to see if it safely helps people with moderate hemorrhoids. If you have stage II or III hemorrhoids and are between 18 and 45, you may be able to join.
IstanbulAges 18–45 - NCT07317492Recruiting
Hemorrhoids and varicose veins study
This study looks at the connection between hemorrhoids and varicose veins. It may help researchers understand if these conditions are related and how to better treat them.
Aydin, EfelerAges 18 years+ - NCT07350460Recruiting
Comparing two pain blocks for hemorrhoid surgery
This study tests two types of numbing injections (a pudendal block and a sacral ESP block) to see which works better for pain after hemorrhoid surgery. If you're scheduled for this surgery, you might qualify to help find a better way to manage pain.
BellinzonaAges 18–80 - NCT07442539Recruiting
Numbing medicine for pain after hemorrhoid surgery
This trial tests a long-acting numbing medicine called liposomal bupivacaine to see if it reduces pain after hemorrhoid surgery better than standard care. It may be an option for people who are otherwise healthy and scheduled for this surgery.
Beijing, Beijing MunicipalityAges 18–64 - NCT07598630Recruiting
Two surgical approaches for severe hemorrhoids
This study compares two different surgical methods for treating severe hemorrhoids (third and fourth degree). The SHAPE procedure is a newer technique being tested against the traditional Milligan-Morgan approach to see which works better for pain relief and recovery.
Cairo, Al-Manial, Cairo, EgyptAges 18 years+ - NCT06748014Enrolling by invitationEarly Phase 1
Study of aescin plus MPFF for bleeding hemorrhoids
This study tests whether a combination of two medicines (aescin and MPFF) can stop bleeding from mild internal hemorrhoids (grade 1 or 2) and prevent it from coming back. If you have had active bleeding within the past 7 days, this trial may help you find an effective non-surgical treatment.
Chiang Mai, MaungAges 20 years+ - NCT07639853Enrolling by invitation
Doctor feedback survey on Concerto Versa coils
This study gathers feedback from doctors who use Concerto Versa detachable coils (small metal devices that help treat brain aneurysms). The survey helps improve how these coils work and are used.
El Paso, TexasAges 22 years+ - NCT07695649Recruiting
Minimally invasive surgery for grade 3 hemorrhoids
This study tests a less invasive surgery for severe hemorrhoids (grades 3 and 4). If you have not had hemorrhoid surgery before and do not have other anal problems, you may be able to join.
Palma de MallorcaAges 18 years+ - NCT06660680Enrolling by invitationPhase 3
Methylene blue for pain after hemorrhoid surgery
This trial tests whether injecting methylene blue (a dye) into the area around the anus during hemorrhoid surgery can reduce pain after the operation. If you are having Milligan-Morgan surgery for mixed hemorrhoids, this study may help find a way to make your recovery more comfortable.
Hefei, AnhuiAges 18–75
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Common questions
- Are there clinical trials for hemorrhoids?
- Yes. Clin2 currently lists 33 recruiting hemorrhoids studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a hemorrhoids trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a hemorrhoids trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.