Clin2
NCT06748014Possibly a fitEnrolling by invitation

Study of aescin plus MPFF for bleeding hemorrhoids

Hemorrhoid

Part of Digestive system, Heart & circulation clinical trials.

This study tests whether a combination of two medicines (aescin and MPFF) can stop bleeding from mild internal hemorrhoids (grade 1 or 2) and prevent it from coming back. If you have had active bleeding within the past 7 days, this trial may help you find an effective non-surgical treatment.

Summary written for real people, not researchers, by Clin2.

Phase
Early Phase 1
Enrollment
120 people
Ages
20 years and older
Study type
Interventional

Who can take part

  • You have internal hemorrhoids grade 1 or 2 that are actively bleeding
  • Your bleeding started within the last 7 days
  • You are at least 20 years old
  • If you are over 50, you must have had a colonoscopy to rule out other causes of bleeding
  • You can come to follow-up visits for up to 6 months

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07128979Recruiting· Phase 4
Studying butcher’s broom for moderate hemorrhoids

This study tests a plant-based medication made from butcher’s broom (Ruscus aculeatus) to see if it safely helps people with moderate hemorrhoids. If you have stage II or III hemorrhoids and are between 18 and 45, you may be able to join.

Istanbul
NCT07026513Recruiting
Aminaphtone and lidocaine spray for hemorrhoids

This trial tests a medication called aminaphtone taken by mouth, combined with a lidocaine spray, to treat painful internal hemorrhoids. It may help reduce symptoms without surgery.

Treviso
NCT07264413Not yet recruiting
Treating bleeding hemorrhoids with coil embolization

This study tests a procedure called hemorrhoidal artery embolization (HAE) using small coils to stop bleeding from grade II or III hemorrhoids (hemorrhoids that protrude but can be pushed back in or come out when you strain). It may be an option if you have significant bleeding and haven't had recent hemorrhoid treatments or certain other conditions.

NCT07669662Not yet recruiting· Phase 3
Herbal treatment for moderate hemorrhoids

This study tests whether an herbal medicine called Nimsai Herbal can help reduce symptoms of moderate hemorrhoids (Grade 2-3). It compares the herbal treatment to a placebo (dummy pill) to see if it works better.

Bursa
NCT07635784Recruiting
Hemorrhoid Treatment Registry: Tracking Embolization Safety

This registry collects information about a minimally invasive procedure called hemorrhoidal artery embolization (HAE), which blocks blood vessels feeding internal hemorrhoids. It's for adults with persistent bleeding hemorrhoids that haven't improved with standard treatments like creams or medications.

Libertyville, Illinois
NCT07647172Not yet recruiting
Flavonoid Treatment for Hemorrhoids After Minimally Invasive Surgery

This study tests whether a plant-based medicine called MPFF (a purified flavonoid fraction) helps reduce symptoms and improve healing after minimally invasive surgery for hemorrhoids. You would take this medicine before and after your scheduled procedure.

Hear when a new Hemorrhoid trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.