Clinical trials
Hereditary Angioedema (HAE) clinical trials
Below are recruiting hereditary angioedema (hae) clinical trials, each written for real people, not researchers. We’re tracking 13 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07298447RecruitingPhase 3
Donidalorsen for children with hereditary angioedema
This study tests a new medicine, donidalorsen, to prevent swelling attacks in children ages 2 to 11 with hereditary angioedema (HAE). If your child has HAE type 1 or 2, this trial may help find a treatment option.
Santa Monica, CaliforniaAges 2–11 - NCT07204938Enrolling by invitationPhase 3
Long-term study of navenibart for hereditary angioedema
This study tests navenibart over a longer period to see if it continues to prevent swelling attacks in people with hereditary angioedema. It is for people who were already in a previous navenibart study.
Scottsdale, ArizonaAges 12 years+ - NCT05396105Enrolling by invitationPhase 2/Phase 3
Oral PHA-022121 extension for hereditary angioedema attacks
This study is an extension trial of an oral medicine (PHA-022121) for treating acute attacks in people with hereditary angioedema (HAE), especially HAE type III (HAE-nC1INH). It checks whether continuing this oral treatment can safely help manage attacks after you’ve taken it before.
Birmingham, AlabamaAges 12 years+ - NCT06679881RecruitingPhase 3
Preventing swelling attacks with oral deucrictibant for HAE
This study tests a long-term daily pill to prevent swelling attacks in people with hereditary angioedema (HAE). The pill, called deucrictibant, is designed to block a protein involved in causing attacks. It's for adolescents and adults who want to reduce how often swelling episodes occur.
Birmingham, AlabamaAges 12 years+ - NCT06960213RecruitingPhase 3
Study of ADX-324 for preventing HAE attacks
This study tests a new medicine called ADX-324 to see if it can prevent HAE attacks in adults with type I or II HAE. If you've had attacks recently and are willing to pause your current prevention medication, this trial may be an option.
Litchfield Park, ArizonaAges 18 years+ - NCT07001280Recruiting
Garadacimab for hereditary angioedema (HAE)
This study looks at how well a drug called garadacimab works and how safe it is for people with hereditary angioedema (HAE), a condition that causes sudden swelling. It tests the drug in people who are starting it for the first time as part of their regular care.
Phoenix, ArizonaAges 12 years+ - NCT07046806RecruitingPhase 1/Phase 2
Oral deucrictibant for hereditary angioedema attacks
This trial tests an oral medication called deucrictibant to prevent and treat swelling attacks in people with hereditary angioedema. It may help reduce the number and severity of attacks.
Wheaton, MarylandAges 18–75 - NCT07263685Recruiting
Study of takhzyro (lanadelumab) for teens and adults with HAE in Saudi Arabia
This study looks at how well Takhzyro (lanadelumab) works for people with a specific type of hereditary angioedema (HAE) that is caused by a C1 inhibitor deficiency. It is for teenagers and adults who have already been taking Takhzyro for at least 6 months.
RiyadhAges 12 years+ - NCT07293364Recruiting
Study of C1-inhibitor test for hereditary angioedema diagnosis
This study checks if a blood test measuring C1-inhibitor function can help diagnose hereditary angioedema (HAE), a rare condition that causes painful swelling episodes. If you or a close family member have had swelling without rash or itching that lasts 1-5 days and doesn't get better with allergy meds, this trial may be for you.
AlgiersAges 12 years+ - NCT07428499RecruitingPhase 3
Long-term safety of ADX-324 for hereditary angioedema
This study is for people who already finished a previous trial of the drug ADX-324 for hereditary angioedema. It tests the long-term safety and effectiveness of continuing the medication.
Litchfield Park, ArizonaAges 18 years+ - NCT04933721Enrolling by invitationPhase 3
Continue berotralstat for people with hereditary angioedema
This study lets people who were already taking berotralstat through earlier BioCryst studies keep the treatment going. It looks at safety and ongoing benefit for preventing hereditary angioedema attacks.
OttawaAges 2 years+ - NCT06361537RecruitingPhase 3
Study of a C1 inhibitor medicine for HAE attacks
This trial tests a plasma-derived C1 esterase inhibitor to treat and prevent acute attacks in people with hereditary angioedema (HAE) types 1 or 2. It aims to see if the medicine can quickly relieve swelling episodes and reduce their frequency.
Centennial, ColoradoAges 2 years+ - NCT03845946Recruiting
CLOUD-R HAE registry for hereditary angioedema patients
This registry study collects information from people with hereditary angioedema (swelling episodes) and related types, with or without a C1-related blood condition. It may help doctors better understand different patterns of swelling and improve future care.
Grenoble, IsereAges Any age
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Hereditary Angioedema (HAE) trials by city
Studies with a site in or near these metro areas.
Hereditary Angioedema (HAE) trials by state
Studies with a site anywhere in these states.
Common questions
- Are there clinical trials for hereditary angioedema (hae)?
- Yes. Clin2 currently lists 13 recruiting hereditary angioedema (hae) studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a hereditary angioedema (hae) trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a hereditary angioedema (hae) trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.