Clinical trials
HIV Prevention clinical trials
Below are recruiting hiv prevention clinical trials, each written for real people, not researchers. We’re tracking 102 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05320835Recruiting
Talk-based overdose prevention for people using opioids
This trial tests an overdose prevention approach for people who have used opioids recently. It aims to help reduce the risk of overdose by offering a structured prevention intervention.
Baltimore, MarylandAges 18 years+ - NCT06962033Recruiting
Pride III: Prison and HIV prevention study
This study looks at ways to improve HIV prevention and treatment for people on probation who have injected opioids. Researchers want to learn from your experiences to help create better services.
New Haven, ConnecticutAges 18 years+ - NCT04979728Recruiting
Check whether home blood drops work for HIV monitoring
This study tests whether people with HIV can safely collect small blood samples at home using finger-pricks and devices (“dried blood spots”). It may help make HIV monitoring easier and more convenient while on certain HIV medicines.
Aurora, ColoradoAges 18 years+ - NCT07495059Recruiting
HIV prevention and care study for transgender women
This trial tests an adapted approach to improve HIV prevention and care for transgender women in Ho Chi Minh City. It aims to help participants stay healthy and access services.
Ho Chi Minh CityAges 16 years+ - NCT07292792Recruiting
PrEP support through peer health navigation for people leaving jail
This study tests whether adding a peer health navigator (someone with lived experience who helps with health) to regular re-entry services can help more people learn about and start PrEP, a medicine that prevents HIV.
Dallas, TexasAges 18–99 - NCT06103370Recruiting
HIV prevention via telemedicine and peer networks
This study tests how well a program combining telemedicine (virtual doctor visits) and peer support can help prevent HIV among people who inject drugs. You'd get trained, attend weekly group sessions, and invite a friend or partner to also take part.
Baltimore, MarylandAges 18 years+ - NCT07834853Recruiting
HIV prevention and care study for Latino men and transgender women
This study helps Latino men, transgender women, and nonbinary people in Washington, DC and the San Francisco Bay Area get HIV prevention or care services. It aims to connect you with health services and support, whether you are living with HIV or want to prevent it.
Berkeley, CaliforniaAges 18 years+ - NCT06493357Recruiting
Improving HIV testing and care for mothers and babies in Malawi
This study is testing a new way to find and treat HIV in pregnant women and new mothers in Malawi. It may help prevent passing HIV from mother to baby.
Lilongwe, Central RegionAges 16 years+ - NCT05404958Recruiting
Improve how HIV prevention and treatment services are integrated
This study looks at ways to better connect HIV prevention services with HIV treatment services in participating clinics. It mainly involves interviewing clinic leaders and staff, plus public health staff, to learn what’s working and how to improve care.
MombasaAges Any age - NCT07231640Recruiting
Improving PrEP care for clinic staff
This study looks at ways to improve PrEP (pre-exposure prophylaxis) care by helping clinic staff track and support patients better. It's for healthcare workers, managers, and data staff at certain PrEP clinics.
Birmingham, AlabamaAges 18 years+ - NCT07053527Enrolling by invitation
Welcome to PrEP School: Peer-led HIV Prevention Study
This study tests if peer educators can help more students start PrEP, a daily pill that prevents HIV. If you are a student at one of the four listed colleges, you may be able to join.
Atlanta, GeorgiaAges 18–26 - NCT06131931Recruiting
HIV prevention study for Latino male couples
This study tests a program to help Latino male couples stay healthy and prevent HIV. It focuses on couples where one or both partners are Latino, and at least one partner has had unprotected anal sex recently.
Orlando, FloridaAges 18–100 - NCT06930508Recruiting
Bringing HIV prevention meds to a family planning clinic
This study looks at offering HIV prevention medicines (PrEP) to patients visiting a family planning clinic. It aims to make it easier for people to access this care alongside their regular visit.
Providence, Rhode IslandAges 16 years+ - NCT07194902Recruiting
HIV self-testing for partners of new and expecting mothers
This study offers HIV self-testing kits to the partners of pregnant women and new mothers who are HIV-negative. It aims to make testing easier and more accessible for partners whose HIV status is unknown.
Durban, KwaZulu-NatalAges 18 years+ - NCT07628140Recruiting
Home-Based TB Prevention Treatment in Kenya
This study tests a community-friendly way to deliver TB prevention medicine (called TPT) to people's homes in Kenya. Researchers want to see if bringing screening and treatment to your house—instead of making you go to a clinic—helps more people start and finish TB prevention, which can reduce TB spread in your community.
KisumuAges Any age - NCT06745947Recruiting
Study to improve HIV prevention habits in young gay and bisexual men
This study tests a new approach to help young gay and bisexual men who take PrEP medication prevent HIV but sometimes miss doses or have condomless sex. It aims to see if behavioral strategies can improve adherence to PrEP and reduce risky behaviors.
San Antonio, TexasAges 18–34 - NCT07186244Recruiting
HIV Prevention Study for People Starting or Taking PrEP
This study is for people who are HIV-negative and want to take PrEP (a daily pill that prevents HIV). It will help researchers learn more about how to best support people taking PrEP in real-world settings.
Chieti, AbruzzoAges 18 years+ - NCT04563715Enrolling by invitation
Study on HIV prevention for at-risk Latino adults
This study looks at ways to prevent HIV in Latino adults who are at higher risk. It may help by testing HIV prevention approaches in specific local communities.
Indianapolis, IndianaAges 18 years+ - NCT07136363Recruiting
RESTORE study: support for stimulant users leaving jail or prison
This trial tests a smartphone app (DynamiCare) to help people recovering from stimulant use (methamphetamine or cocaine) stay healthy after leaving jail or prison. It also focuses on those at risk for or living with HIV.
New Haven, ConnecticutAges 18 years+ - NCT06474364RecruitingPhase 4
HIV prevention and care for youth in Uganda
This study tests ways to help young people in Uganda prevent HIV or stay healthy if they already have HIV. It offers free prevention pills or injections and care for those living with HIV.
KampalaAges 15–24 - NCT06230367Recruiting
Text program for HIV prevention for young guys who like guys
This trial tests a text-messaging program to help young guys who have sex with guys stay HIV-negative. It's designed for teens and young adults who own a cell phone and can take a quick HIV test at home.
San Clemente, CaliforniaAges 13–22 - NCT06074354Recruiting
MY-RIDE app for HIV prevention and substance use in homeless youth
This study tests a smartphone app called MY-RIDE to help homeless youth prevent HIV and reduce substance use. The app sends helpful tips at the right time to support healthier choices.
Houston, TexasAges 18–25 - NCT05669534RecruitingPhase 4
HIV prevention support for people starting PrEP
This study tests how to better support HIV prevention for people who inject drugs and are newly starting PrEP (medicine to prevent HIV). It focuses on people taking medication for opioid use disorder and who have mild thinking and memory problems, to help them stay safe and adhere to prevention.
New Haven, ConnecticutAges 18 years+ - NCT07614165Enrolling by invitation
HIV Prevention Decision Tool for Young Adults
This study tests a simple online tool to help young people decide whether PrEP (a daily pill that prevents HIV) might be right for them. The tool uses information from an at-home HIV test and is designed to make PrEP information easier to understand.
Ann Arbor, MichiganAges 18–39
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Common questions
- Are there clinical trials for hiv prevention?
- Yes. Clin2 currently lists 102 recruiting hiv prevention studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a hiv prevention trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a hiv prevention trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.