Clinical trials
HIV Prevention clinical trials
Below are recruiting hiv prevention clinical trials, each written for real people, not researchers. We’re tracking 100 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07160075RecruitingPhase 4
HIV prevention with PrEP for people on opioid therapy
This trial tests if daily PrEP medication can help prevent HIV in people receiving opioid replacement therapy. You must be HIV-negative and regularly attend your opioid treatment program to join.
Calgary, AlbertaAges 16 years+ - NCT06666309Enrolling by invitation
Study on HIV prevention for people who inject drugs
This study tests different ways to help people who inject drugs stay on PrEP, a daily pill that prevents HIV. It's for people who are HIV-negative and have recently injected drugs.
Barbourville, KentuckyAges 18 years+ - NCT07574619Recruiting
HIV Prevention Choices for Women in Uganda: Couples Study
This research tests a tool that helps women and their partners make informed decisions about PrEP (a daily pill that prevents HIV). The study involves healthcare workers, patients, and leaders in Uganda to improve how women choose and use HIV prevention.
KampalaAges 18 years+ - NCT06703060Recruiting
A trauma-informed approach to help Black women start PrEP
This study tests a program that helps Black women start PrEP (a daily pill to prevent HIV). It focuses on understanding and addressing past trauma to make it easier to take PrEP, and is designed for women who have not used PrEP before.
Baltimore, MarylandAges 18 years+ - NCT07584122Recruiting
Increasing HIV Prevention Access in Rio de Janeiro
This study helps people at higher risk of HIV get access to PrEP, a daily medication that prevents HIV infection. The program focuses on underserved communities in Rio de Janeiro and aims to make PrEP easier to access and use.
Nova Iguaçu, Rio de JaneiroAges 15 years+ - NCT07339189Recruiting
AI Suicide Prevention for Older Adults With HIV
This trial tests a smartphone-based AI program designed to help people with HIV who have had suicidal thoughts. It aims to reduce suicide risk by teaching coping skills through text-based conversations.
Newark, New JerseyAges 50 years+ - NCT07119359Recruiting
TB and HIV prevention study for households in Uganda
This study tests whether adding HIV prevention services to routine TB household contact checks can help more people stay healthy. If you or someone you live with has TB, you may be able to join.
KampalaAges 15 years+ - NCT05075967Enrolling by invitation
Study attitudes and services among southern gay and bisexual men
This study gathers opinions and experiences from gay and bisexual men and from clinic staff in the American South. It helps researchers understand what affects HIV prevention and care, and how programs can better support people at higher risk.
Durham, North CarolinaAges 15 years+ - NCT07505875Recruiting
Study to create transgender-friendly services for chemsex support
This study aims to develop healthcare services tailored to transgender people regarding chemsex (using drugs during sex). Researchers will interview participants to understand their needs and experiences.
Pathum Wan, BangkokAges 18 years+ - NCT07512856Recruiting
Support Service for Transgender People Using Substances
This study tests a new support program designed specifically for transgender people who use drugs or engage in chemsex (using drugs during sexual activity). The program aims to reduce health risks and provide safer, more culturally respectful care.
Pathum Wan, BangkokAges 18 years+ - NCT07433985Recruiting
California mobile app study for men after jail release
This study tests a mobile app to help men recently released from jail or prison who use drugs or have sex with men stay healthy and avoid HIV. It's for people who don't have HIV and live in certain California counties.
Oakland, CaliforniaAges 18–59 - NCT06807736Recruiting
Choosing injectable PrEP for HIV prevention in Cape Town
This study offers three ways to prevent HIV: a shot every two months (injectable PrEP), daily pills, or a vaginal ring. Researchers in Cape Town will help you choose the option that fits your life best.
Cape Town, Western ProvinceAges 15 years+ - NCT07509853Recruiting
Pleasure-Focused Harm Reduction for Chemsex and Substance Use
This study explores how adding conversation about sexual pleasure to harm reduction services can help men who have sex with men and transgender persons who use drugs during sex or use other substances. If you join, you may learn new ways to reduce risks while still enjoying your sex life.
Pathum Wan, BangkokAges 18 years+ - NCT07512869Recruiting
Harm Reduction Support for Men Who Have Sex With Men in Bangkok
This study explores ways to support men who have sex with men (MSM) in Bangkok who use drugs during sexual activities, called 'chemsex.' Researchers want to understand how community leaders, healthcare workers, and police can work together to keep people safer and healthier.
Pathum Wan, BangkokAges 18 years+ - NCT06656676Recruiting
WePrEP: HIV prevention tool for transgender women
This study is creating a decision-making tool to help transgender women choose the right PrEP (HIV prevention pill) for them. It is looking for transgender women in Denver who are HIV-negative and interested in learning more about PrEP, as well as healthcare providers who help transgender women decide about PrEP.
Sheridan, ColoradoAges 18–65 - NCT05165745Recruiting
Study of PrEP choices in women and transgender people
This study asks people who may use PrEP—an HIV prevention medicine—about their decision to start, not start, or stop PrEP. It aims to understand needs and barriers so PrEP can work better for cisgender women and transgender people who are considering it.
New York, New YorkAges 18 years+ - NCT02437981Enrolling by invitation
PrEP for HIV prevention in high-risk adults in Thailand
This trial checks how well PrEP pills (TDF/FTC) prevent HIV in people who are at high risk and are HIV-negative. It may help you understand whether PrEP is a good prevention option for your situation.
Bangkok, PathumwanAges 18 years+ - NCT07497594Recruiting
Twice-yearly shots to prevent HIV
This trial tests a new HIV prevention medicine called lenacapavir, given as a shot every six months. It's for young people at risk of HIV who haven't used PrEP before or have had gaps in their PrEP use.
Manaus, AmazonasAges 16–30 - NCT07349758RecruitingPhase 1
Single dose of two PrEP tablets in healthy volunteers
This study tests how taking two tablets of a PrEP medication (F/TAF) at once affects healthy volunteers. It helps us understand the safety and how the body processes the drug.
Baltimore, MarylandAges 18 years+ - NCT05804461Recruiting
PrEP support study for Latino gay and bisexual men in Puerto Rico
This study tests ways to help Latino men who have sex with men use PrEP, a medicine that helps prevent HIV. You may be invited if you are HIV-negative (or your status is unknown), are not currently on PrEP, and can read and write Spanish.
San JuanAges 21–99 - NCT06485154RecruitingPhase 4
Finding the best HIV treatment after PrEP shot failure
This trial is for people who got exposed to HIV despite taking the long-acting PrEP shot (cabotegravir). It tests different pill-based HIV treatment plans to find the best option for them.
Johannesburg, GautengAges 15 years+ - NCT07467018Recruiting
Mobile van study of a long-acting HIV prevention shot
This study tests if giving a long-acting HIV prevention shot (lenacapavir) from a mobile medical van can reach people at risk for HIV in Los Angeles County. You may be able to join if you are HIV negative, at risk for HIV, and are willing to try a shot instead of a daily pill.
Santa Monica, CaliforniaAges 18 years+ - NCT06845774Enrolling by invitation
PrEP support via telehealth for people who inject drugs
This trial tests whether telehealth support can help people who inject drugs start and stay on PrEP (HIV prevention medicine). You will join several sessions and follow-up visits to see if this approach works better than standard care.
Lexington, KentuckyAges 18–99 - NCT06158126RecruitingPhase 4
Pregnancy and infant health outcomes study
This study follows pregnant women and their babies to see how well HIV prevention medicines work during pregnancy. It aims to help keep both mother and baby healthy.
LilongweAges 15–55
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Common questions
- Are there clinical trials for hiv prevention?
- Yes. Clin2 currently lists 100 recruiting hiv prevention studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a hiv prevention trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a hiv prevention trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.