Clinical trials
HIV Treatment clinical trials
Below are recruiting hiv treatment clinical trials, each written for real people, not researchers. We’re tracking 87 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05419024RecruitingPhase 2
Imaging and biopsy during a planned HIV treatment pause
This Phase 2 study uses special scans (PET/CT) and tissue sampling (biopsy) to learn what is happening in the body while people with HIV take a planned break from antiretroviral therapy (ART) for up to 90 days. It may help researchers find better ways to control HIV without ongoing treatment, though joining involves careful monitoring during the pause.
Bethesda, MarylandAges 18–100 - NCT02437526Enrolling by invitation
Testing an HIV treatment pause to see if cure is possible
This study looks at whether some people with HIV can keep the virus controlled even if they temporarily stop HIV medicines (an “analytic treatment interruption”). If you qualify, it may help researchers learn what it would take for an HIV cure.
Rochester, MinnesotaAges 18 years+ - NCT05384145Recruiting
Improve HIV testing and follow-up in Alabama clinics
This trial is testing a “whole-people” plan to help more people get HIV tested, get connected to care, and stay on treatment. It is mainly for healthcare and community staff in specific Alabama counties.
Birmingham, AlabamaAges 13 years+ - NCT07439003Recruiting
HIV treatment decision support program
This study is testing a program to help people with HIV stick with their medication. It looks at how well doctors and patients work together to make treatment decisions and improve health outcomes.
Johannesburg, GautengAges 18 years+ - NCT06749054RecruitingPhase 2
Long-acting HIV treatment for teens and children with drug resistance
This trial tests a long-acting injection called lenacapavir for children and teens with HIV who have tried other treatments and still have detectable virus. It may be an option if current medicines aren't working well enough.
Atlanta, GeorgiaAges Up to 17 years - NCT04979728Recruiting
Check whether home blood drops work for HIV monitoring
This study tests whether people with HIV can safely collect small blood samples at home using finger-pricks and devices (“dried blood spots”). It may help make HIV monitoring easier and more convenient while on certain HIV medicines.
Aurora, ColoradoAges 18 years+ - NCT07393659RecruitingPhase 3
Continued access to HIV treatment after a parent study
This study lets people who finished an earlier HIV treatment study keep getting the same medicine while a new trial is set up. It helps ensure you don't have a gap in your treatment.
Durban, KwaZulu-NatalAges Any age - NCT06337032RecruitingPhase 4
Continued access to HIV treatment for children and teens
This trial provides continued access to Biktarvy (B/F/TAF) for children and adolescents who completed a previous Gilead HIV study. It ensures they can keep taking the medication without interruption.
Buenos AiresAges 1 month+ - NCT07502365Recruiting
Guaranteed income for young adults living with HIV
This study tests whether providing a basic income (no-strings-attached cash payments) can help young people with HIV stay healthy and engaged in care. If you qualify, you would receive regular payments and the research team would track your health over time.
Chicago, IllinoisAges 18–35 - NCT07708727RecruitingPhase 2/Phase 3
Injectable HIV treatment vs daily pill for new patients
This trial tests a new injectable HIV treatment (GS-3242 plus lenacapavir) compared to the daily pill Biktarvy for people just starting HIV therapy. If you qualify, you would receive shots every few weeks instead of taking a daily pill.
Ft. Pierce, FloridaAges 18 years+ - NCT07032363Recruiting
Depression and HIV treatment support study
This study tests a program that helps people with HIV manage depression and stick to their treatment. It's for adults in Cape Town, South Africa, who have a detectable HIV viral load or may have one, and who show signs of depression.
Miami, FloridaAges 18 years+ - NCT06668363Recruiting
HIV prevention and alcohol reduction for STI clinic patients
This study tests a program to help people receiving STI care reduce heavy drinking and prevent HIV. It may be a good fit if you drink heavily and want support with HIV prevention or treatment adherence.
LilongweAges 18 years+ - NCT07329166Recruiting
Reducing HIV treatment interruptions in Malawi
This study tests a program to help people in Malawi stay on their HIV treatment even when they travel or move around. Researchers want to know if extra support can prevent gaps in care.
LilongweAges 15 years+ - NCT05404958Recruiting
Improve how HIV prevention and treatment services are integrated
This study looks at ways to better connect HIV prevention services with HIV treatment services in participating clinics. It mainly involves interviewing clinic leaders and staff, plus public health staff, to learn what’s working and how to improve care.
MombasaAges Any age - NCT07220278Recruiting
HIV treatment support study in Malawi
This study tests a program to help people living with HIV who have missed their recent treatment appointment get back on track. It aims to find better ways to support ongoing treatment.
LilongweAges 15 years+ - NCT06488846Enrolling by invitation
Giving HIV injections at home with a helper
This study tests whether having a trained friend or family member give you your HIV injections at home is safe and works as well as getting them at a clinic. You may qualify if you are already on the injectable HIV medication cabotegravir/rilpivirine (Cabenuva) and have a support person willing to help.
San Francisco, CaliforniaAges 18 years+ - NCT04577313Recruiting
Study to improve HIV medicine adherence reminders
This study looks at a way to help people take their HIV medicines as prescribed. It focuses on people who are HIV-positive and not currently taking their treatment consistently.
Storrs, ConnecticutAges 18 years+ - NCT07683000RecruitingPhase 3
Study of three HIV drugs for adults with controlled HIV
This trial tests a new combination of three medications, lenacapavir, teropavimab, and zinlirvimab, for people with HIV who currently have undetectable virus levels on a stable oral treatment. The goal is to see if these drugs can keep the virus suppressed, possibly allowing a simpler treatment plan.
Berkeley, MichiganAges 18 years+ - NCT06762730RecruitingPhase 4
Zoledronic acid to prevent bone loss from HIV treatment
This trial tests if zoledronic acid, a drug that strengthens bones, can prevent bone loss caused by starting HIV treatment. It is for people newly diagnosed with HIV who have not yet taken any HIV medication.
HaifaAges 18 years+ - NCT07643948Recruiting
How HIV Treatment Changes Affect Drug Resistance
This study follows people with HIV whose virus is well-controlled on current medications to understand how switching to a different HIV drug regimen affects the virus's ability to resist those drugs. The goal is to help doctors choose the safest treatment switches.
Hong Kong, Hong KongAges 18 years+ - NCT06928090Enrolling by invitation
HIV trial testing two-med combo for first-time treatment
This trial studies a two-drug pill (DTG/3TC) for people who have never taken HIV medication before. It aims to see if this simpler treatment is effective and safe for controlling HIV-1.
DaejeonAges 19 years+ - NCT06967519RecruitingPhase 4
Optimizing malaria and HIV treatment in Africa
This study aims to find the best way to treat or prevent malaria in children with HIV. It may also help children without HIV who live in areas where malaria is common.
KampalaAges 5–17 - NCT05958017Recruiting
ReSET program to help stimulant use in HIV clinics
This study tests a care-support program called ReSET to improve adherence to treatment and reduce stimulant use for people living with HIV who are not currently in drug treatment. You may be offered support through HIV clinic care to help you stay on track, especially if you have access to a smartphone and stable housing.
Miami, FloridaAges 18–90 - NCT07732660Recruiting
Building skills and reducing stigma for young people with HIV in Zambia
This trial helps young people aged 18 to 24 living with HIV in three districts of Zambia. It aims to reduce stigma and build job skills to improve their lives.
Lusaka, Lusaka ProvinceAges 18–24
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Common questions
- Are there clinical trials for hiv treatment?
- Yes. Clin2 currently lists 87 recruiting hiv treatment studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a hiv treatment trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a hiv treatment trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.