Clinical trials
Homelessness clinical trials
Below are recruiting homelessness clinical trials, each written for real people, not researchers. We’re tracking 18 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05823220Enrolling by invitation
Homelessness support added to hospital discharge planning
This trial tests whether adding homelessness “diversion” services to emergency department discharge plans can help people avoid becoming homeless. It may be helpful if you’ve just left the hospital and you’re at high risk of housing instability.
Houston, TexasAges 18 years+ - NCT06821295RecruitingPhase 2/Phase 3
Smartphone app to help reduce drinking at shelters
This trial tests a smartphone app that gives you personal tips to help you drink less alcohol, especially if you are staying at or getting services from a shelter. The app sends you messages at the right times to help you cut back on drinking.
Oklahoma City, OklahomaAges 18 years+ - NCT06138054Recruiting
Mobile Program for Veterans with Mental Illness and Homelessness History
This trial tests a smartphone-based program to help veterans with serious mental illness who have experienced homelessness feel more connected to their community. It aims to see if the mobile coaching can improve daily living skills and reduce feelings of isolation.
West Los Angeles, CaliforniaAges 18–65 - NCT06311838Recruiting
Preventing opioid use among homeless youth
This study tests a program to help homeless youth build social connections and find stable housing to prevent opioid use. It will be conducted by Ohio State University.
Columbus, OhioAges 14–24 - NCT06869915Recruiting
Study on homelessness and brain development conditions
This study looks at how common certain brain development conditions (like ADHD or autism) are in people experiencing homelessness. Researchers hope to better understand the needs of this group.
Lyon, Auvergne-Rhône-AlpesAges 18–90 - NCT07091487Recruiting
Diabetes Homeless Medication Support Program
This study tests a program that helps people who have both type 2 diabetes and housing instability. The program supports you in taking your medication and managing your diabetes day-to-day.
Minneapolis, MinnesotaAges 18 years+ - NCT07209072Recruiting
Emergency room help for homeless patients after discharge
This study connects homeless patients leaving the emergency room to a mobile health team that can follow up with them in the community. It aims to help people with certain conditions like asthma, pneumonia, infections, or injuries get the care they need.
Denver, ColoradoAges 18 years+ - NCT07419282Recruiting
Supporting young adults leaving homelessness with housing and job help
This trial tests a program called SEED CHANGE that provides coaching, group support, and employment help to young adults aged 18-24 who have experienced homelessness. It aims to help them keep stable housing and build a better future.
Toronto, OntarioAges 18–24 - NCT05994612Recruiting
Suicide prevention for homeless youth using substances
This trial tests a program to help reduce suicide risk in young people who are homeless and use alcohol or drugs. It may provide support and strategies to keep them safe.
Columbus, OhioAges 15–24 - NCT05312229RecruitingPhase 1
Aftercare support for Veterans after homelessness
This Phase 1 study is testing a housing transition approach for Veterans who have recently experienced homelessness. It focuses on case management support after discharge, using an existing aftercare program structure.
West Los Angeles, CaliforniaAges Any age - NCT05616026Recruiting
Text message support to improve diabetes control
This trial tests whether regular text messages can help people who are homeless manage type 2 diabetes better. It focuses on improving blood sugar control, often tracked by a lab result called HbA1c.
Washington D.C., District of ColumbiaAges 21 years+ - NCT06074354Recruiting
MY-RIDE app for HIV prevention and substance use in homeless youth
This study tests a smartphone app called MY-RIDE to help homeless youth prevent HIV and reduce substance use. The app sends helpful tips at the right time to support healthier choices.
Houston, TexasAges 18–25 - NCT06239896Recruiting
Advance care planning for older adults in supportive housing
This study explores how to help older adults who were once homeless and now live in supportive housing make plans for their future medical care. Participants will talk about their health care wishes with a trained guide.
Fremont, CaliforniaAges 50 years+ - NCT06620601Recruiting
Digital technology for sleep and homelessness
This study explores how digital tools can help improve sleep for people living in shelters. It aims to test whether wearable devices or apps can support better sleep habits and health.
Toronto, OntarioAges 18 years+ - NCT06723093Recruiting
Housing and health study for homeless adults
This study looks at how a supportive housing program helps adults who are homeless and have complex health needs. If you qualify for the housing program, you can choose to join the research.
Toronto, OntarioAges 18 years+ - NCT07148232RecruitingPhase 4
Helping people experiencing homelessness quit smoking
This study tests an extended program to help people who are homeless and smoke at least 5 cigarettes a day quit smoking. It provides nicotine replacement therapy (like patches or gum) and support over time.
San Francisco, CaliforniaAges 18 years+ - NCT07470372Enrolling by invitation
Work and housing program for adults at risk of homelessness
This study tests whether a program that offers housing help and job support can keep adults from becoming homeless. If you have recently been in an emergency department and are worried about losing your home or finding work, this may be a good fit for you.
Houston, TexasAges 18 years+ - NCT05698498Enrolling by invitation
Guaranteed income support for families experiencing homelessness
This study tests whether a guaranteed income helps families who are experiencing homelessness in Santa Clara County. The goal is to see if steady money makes it easier to find and keep housing and get life back on track.
San Jose, CaliforniaAges 18 years+
Hear when a new Homelessness trial opens
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Homelessness trials by city
Studies with a site in or near these metro areas.
Homelessness trials by state
Studies with a site anywhere in these states.
Common questions
- Are there clinical trials for homelessness?
- Yes. Clin2 currently lists 18 recruiting homelessness studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a homelessness trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a homelessness trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.