Clinical trials
Immunodeficiency clinical trials
Below are recruiting immunodeficiency clinical trials, each written for real people, not researchers. We’re tracking 132 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT01861106RecruitingPhase 2
Bone marrow transplant for people with GATA2 gene changes
This trial tests whether an allogeneic bone marrow (stem cell) transplant can improve outcomes for people with GATA2 gene changes or “MonoMAC” syndrome. It aims to rebuild a healthier immune system in patients who have serious infections and immune cell deficiencies.
Bethesda, MarylandAges 6–70 - NCT02356653RecruitingEarly Phase 1
Stem cell transplant help for children lacking a matching sibling
This expanded-access study offers a specific type of stem cell transplant preparation that removes certain immune cells (CD3 and CD19) from donor stem cells. It is for children who need a transplant but do not have a fully matched sibling donor and whose team cannot use the hospital’s usual matching device protocol.
Philadelphia, PennsylvaniaAges Up to 30 years - NCT01186913Enrolling by invitation
Natural history study for severe combined immune deficiency (SCID)
This study follows children and adults with SCID and related immune disorders to understand how the illness behaves over time. It also helps researchers learn which testing results and genetic types of SCID match different treatment plans.
Birmingham, AlabamaAges Any age - NCT07406217RecruitingPhase 2
Optimizing antivirals for immunocompromised COVID-19 patients
This trial tests whether an optimized antiviral treatment can help people with weakened immune systems who have COVID-19. It aims to find the best way to treat them to prevent severe illness.
Basel, BaselAges 16 years+ - NCT07418385Recruiting
Voluntary HIV testing for adults in France
This study offers free, voluntary HIV testing to anyone in France who is 18 or older. It aims to make HIV screening easy and accessible, regardless of your sexual history or past testing.
ReimsAges 18 years+ - NCT07495059Recruiting
HIV prevention and care study for transgender women
This trial tests an adapted approach to improve HIV prevention and care for transgender women in Ho Chi Minh City. It aims to help participants stay healthy and access services.
Ho Chi Minh CityAges 16 years+ - NCT07541131Enrolling by invitation
Reducing HIV stigma to improve treatment access for drug users
This study tests whether reducing stigma and discrimination against people who use drugs can help more people access HIV treatment and prevention. You would participate in peer-led group sessions and surveys over 18 months to help researchers understand how stigma affects treatment access in Bishkek.
BishkekAges 18 years+ - NCT07279376Enrolling by invitation
Using an algorithm to improve HIV care for health home members
This study tests a computer-based algorithm to help improve HIV care for people who are part of a special care management program called a Health Home. It aims to make sure you get the support and treatment you need.
New York, New YorkAges 18 years+ - NCT07064928Enrolling by invitation
Reducing HIV stigma in pregnancy and after birth
This study tests a program to reduce stigma related to HIV among pregnant women and new mothers. You may be eligible if you are living with HIV, are between 24 and 36 weeks pregnant, and plan to stay in the area for at least 6 months after your baby is born.
AccraAges 14 years+ - NCT06604663Enrolling by invitation
Using data to improve HIV care in Kenya
This trial is looking at how to improve HIV care by using data and interviews to help clinics make better decisions. It doesn't require you to do anything different—your regular clinic data will be used to see how well appointments are kept.
EldoretAges 18–100 - NCT04049084Enrolling by invitation
Follow-up study for people treated with gene therapy for ADA-SCID
This is a follow-up (no new treatment) study for people who previously received a gene therapy made from their own cells for ADA-SCID. It mainly tracks long-term safety and whether a marker showing the gene change can still be found.
Los Angeles, CaliforniaAges Any age - NCT03478670Enrolling by invitation
Registry follow-up for ADA-SCID patients treated with Strimvelis
This study keeps track of people with ADA-SCID (a rare immune system condition) who previously received Strimvelis or a related treatment. It helps doctors understand long-term outcomes and safety after treatment.
Milan, LombardyAges Any age
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Common questions
- Are there clinical trials for immunodeficiency?
- Yes. Clin2 currently lists 132 recruiting immunodeficiency studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a immunodeficiency trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a immunodeficiency trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.