Clinical trials
Low Back Pain clinical trials
Below are recruiting low back pain clinical trials, each written for real people, not researchers. We’re tracking 348 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06620133Recruiting
Pain education and goal setting for chronic low back pain
This trial tests whether learning about pain and setting your own exercise goals helps people with long-term low back pain become more active. You will receive online sessions and support to safely increase your physical activity.
Sydney, New South WalesAges 18 years+ - NCT05721027RecruitingPhase 4
Ibuprofen alone or with a steroid for new sciatica pain
This trial compares ibuprofen alone versus ibuprofen plus dexamethasone (a steroid) for short-term relief of acute nerve-related low back pain that shoots into the buttock or leg. It aims to see which approach reduces pain and improves function after an emergency visit.
The Bronx, New YorkAges 18–70 - NCT06924671Recruiting
GLA:D Back Canada program for chronic low back pain
This study tests a program called GLA:D Back Canada, which is designed to help people with long-lasting low back pain. It focuses on exercises and education to improve your back health and daily function.
Edmonton, AlbertaAges 18 years+ - NCT07523906Recruiting
Exercise therapy for chronic lower back pain in young adults
This study compares two types of exercise programs for chronic mechanical lower back pain: lumbar stabilization exercises (focused on core strength) versus muscular chain therapy (full-body movement patterns). You'll participate in one of these exercise programs to see which helps reduce your pain more effectively.
IslamabadAges 18–30 - NCT07426562Recruiting
Stretching vs. Dry Needling for Tight Hamstrings in Chronic Back Pain
This trial tests two treatments for tight hamstrings in people with long-lasting low back pain: a special stretch and dry needling (thin needles placed in trigger points). It aims to find which helps reduce tightness and pain.
Peshawar, Khyber PakhtunkhwaAges 20–50 - NCT07433634Recruiting
Tracking recovery after BVN ablation for chronic low back pain
This study looks at how well a procedure called BVN ablation (which uses heat to stop pain signals from the vertebrae) works for people with chronic low back pain that comes from the spine. If you already have this procedure scheduled, researchers will track your recovery and pain relief over time.
Guilford, ConnecticutAges 18 years+ - NCT07415941Recruiting
Mindfulness and nerve stimulation for back pain and depression
This trial tests if combining mindfulness-based meditation with a gentle nerve stimulation device (applied to the ear) can help people aged 50–85 with chronic low back pain and depression. The goal is to reduce pain and improve mood without changing your current medications.
Tallahassee, FloridaAges 50–85 - NCT07413107Recruiting
Italian version of a back pain disability questionnaire
This study is testing a new Italian questionnaire that measures how much low back pain affects your daily life. It's for people who have had low back pain for at least 3 months and speak Italian.
Lissone, MilanoAges 18–90 - NCT07127380Recruiting
Comparing two types of spine surgery for disc-related low back pain
This study compares two different surgery methods (Mini-TLIF and MIDLIF) for treating low back pain caused by worn-out discs in the lower back. The goal is to see which one offers better recovery, fewer complications, and lower costs.
Lodz, Łódź VoivodeshipAges 18 years+ - NCT07392333Recruiting
Nerve ablation for chronic low back pain
This study tests a treatment that uses radiofrequency energy to target specific nerves in the spine that may be causing your low back pain. If you qualify, you would receive the OptaBlate BVN procedure and be followed over time to see how well it works.
Fort Lauderdale, FloridaAges 22 years+ - NCT07535047Recruiting
How Placebo and TENS Work Together for Lower Back Pain
This study tests whether the expectation of pain relief (the placebo effect) can make a device called TENS (transcutaneous electrical nerve stimulation) work better for acute lower back pain. TENS uses gentle electrical pulses on your skin to reduce pain.
Giza, Giza GovernorateAges 18–65 - NCT06718348Recruiting
Lumbar Traction Device for Low Back Pain
This trial tests a supportive device (Japet.W+) that gently pulls on your lower back to help reduce pain. If you have had low back pain for more than 6 weeks without a specific cause, you may join.
Charleroi, HainautAges 18 years+ - NCT07386548Recruiting
Biologic injection for low back disc problems
This study tests if an injection can help people with a herniated disc in the lower back who have not gotten better with other treatments and are already planning surgery. It aims to see if the injection can reduce symptoms and possibly avoid or improve surgery outcomes.
Manhattan, New YorkAges 18 years+ - NCT07375914Recruiting
New approach for managing acute low back pain in the ER
This trial tests a comprehensive program that looks at your physical, mental, and social needs to treat sudden low back pain in the emergency room. It may help you get better care and avoid long-term pain.
ParisAges 18–55 - NCT07362420Recruiting
Exercise and pressure-point therapy for long-term low back pain
This study compares two treatments for low back pain that has lasted more than six weeks: a special exercise program and a hands-on therapy that targets muscle knots (trigger points). The goal is to see which approach better reduces pain and improves function.
Taipei, Taipei CityAges 18–65 - NCT07366827Recruiting
Motorized back support for low back pain
This trial tests a motorized lumbar support device to see if it can relieve non-specific lower back pain. It may help if your pain gets better with gentle stretching or pulling of the spine (called manual traction).
Québec, QuebecAges 18–65 - NCT07368920Recruiting
TENS for low back pain in adults
This study tests if a non-invasive device called TENS (which uses gentle electrical pulses) can help relieve low back pain that comes from muscle knots or tight bands. The device is applied to the skin over the painful area.
Xi'an, ShaanxiAges 18–65 - NCT07359144Recruiting
Pilates for low back pain after childbirth
This study tests whether Pilates exercises can help relieve low back pain in women who have had a baby. It focuses on pain that started after childbirth and lasts for more than three months.
Kafr ash Shaykh, KafrelsheikhAges 20–30 - NCT07463105Recruiting
Virtual reality vs. standard rehab for chronic back pain
This study compares virtual reality exercises to standard physical therapy for people with ongoing low back pain. It aims to see if VR can be a helpful and engaging way to reduce pain and improve function.
Sanok, Podkarpackie VoivodeshipAges 40–65 - NCT07351851Recruiting
Exercise for back pain and urine leakage in women
This study tests whether a special exercise program called PEMM (which combines pelvic floor and core exercises) can help women with both chronic low back pain and urinary incontinence. It is designed for women who have had back pain and urine leakage for at least 3 months.
Doha, Baladiyat ad DawhahAges 18–65 - NCT07347457Enrolling by invitation
Rehab and pain relief for chronic low back pain
This trial tests whether a functional rehabilitation program can improve how your body naturally reduces pain after exercise. It may help people with chronic low back pain who are starting a rehab program.
Villeneuve-d'AscqAges 18–60 - NCT07339631RecruitingPhase 1
Sodium Aescinate for Chronic Low Back Pain in Adults
This study tests an injectable medication called sodium aescinate (derived from horse chestnut) for people with chronic low back pain. It aims to see if it helps reduce pain and is safe to use.
Xi'an, ShaanxiAges 18–65 - NCT07334756Recruiting
Mobilization therapy for long-term low back pain
This study tests gentle back movements (not forceful adjustments) to see if they help relieve low back pain that has lasted more than 3 months. If you have low back pain without leg pain, this may be an option to try.
Islamabad, Punjab ProvinceAges 18–45 - NCT07338877Enrolling by invitation
Stem cell therapy for disc-related low back pain
This trial tests a new treatment that uses your own stem cells to help heal damaged discs in your lower back. The stem cells are injected into the disc during a minimally invasive procedure to reduce pain and improve function.
Košice, Košice RegionAges 18 years+
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Low Back Pain trials by city
Studies with a site in or near these metro areas.
Low Back Pain trials by state
Studies with a site anywhere in these states.
Common questions
- Are there clinical trials for low back pain?
- Yes. Clin2 currently lists 348 recruiting low back pain studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a low back pain trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a low back pain trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.