Clinical trials
Mental Health clinical trials
Below are recruiting mental health clinical trials, each written for real people, not researchers. We’re tracking 725 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06254924Recruiting
Qoyangnuptu app for southwestern tribal youth
This study tests a smartphone app called Qoyangnuptu for young people from Southwestern Tribal communities. The app is designed to support your wellbeing, and taking part could help you build healthy habits.
Flagstaff, ArizonaAges 14–25 - NCT07284368Enrolling by invitation
Advance Choice Document study for mental health care
This study looks at how Advance Choice Documents (ACDs) can help people who have been detained under the Mental Health Act. It aims to understand how these documents are made and used, so that future care can better respect your wishes.
LondonAges 16 years+ - NCT07281729Enrolling by invitation
Suicide risk factors study for mood disorders
This study looks at why some people with mood disorders (like depression or bipolar disorder) think about or attempt suicide. By finding the risk factors, doctors hope to better prevent suicide. The study involves filling out questionnaires.
Shanghai, Shanghai MunicipalityAges 16–60 - NCT07271485RecruitingEarly Phase 1
Propranolol for misophonia: a pilot study
This trial tests if a blood pressure medication called propranolol can reduce the intense anger or anxiety some people feel in response to everyday sounds (like chewing or breathing). If you have misophonia and meet the study’s health and safety criteria, you may be able to join and receive the medication under medical supervision at a clinic in Littleton, Colorado.
Littleton, ColoradoAges 18–65 - NCT05352061Enrolling by invitation
HIV support program for people with mental health and life challenges
This study looks at how an HIV treatment and prevention program can be improved for people who have HIV plus psychosocial challenges, especially when HIV is not well controlled. You may be able to join if your HIV is recent and higher than target, and you fit one of the specific participant groups.
Miami, FloridaAges 18 years+ - NCT06868966Recruiting
Study of myelin in brain control for ages 10 to 25
This study looks at how myelin (the insulation around brain cells) affects your ability to control and coordinate movements. It involves an MRI brain scan and may help scientists understand brain development in young people.
ParisAges 10–25 - NCT06862193Recruiting
A mental health app study for pregnant women
This trial tests a digital app (HM4MH) to support psychological well-being during and after pregnancy. It is for pregnant women who own a smartphone and are in early pregnancy.
JönköpingAges 18 years+ - NCT07529548Recruiting
New Beginnings Podcast for Divorced and Separated Parents
This study tests a podcast designed to help parents who are divorced or separated navigate co-parenting and support their children's wellbeing. You and your child would listen to audio content and answer some questions about how you're doing.
Tempe, ArizonaAges 8 years+ - NCT07217561Recruiting
Doula support program to improve mental health before and after birth
This trial tests whether extra training and resources for doulas can help pregnant people and new parents feel better emotionally. Doulas who join will learn new ways to support clients, and participants will get care from a trained doula.
Boston, MassachusettsAges Any age - NCT07195721Recruiting
How special contact lenses affect mental health
This study looks at whether PROSE or scleral lenses can improve mental health in people with certain eye surface conditions. It may be a good fit if you have a dry eye or related disease and are considering these lenses.
Needham, MassachusettsAges Any age - NCT07091240Recruiting
Building resilience in toddlers: a screening program
This study tests a program that helps doctors identify toddlers who might need extra support with their emotional or behavioral health. It is designed for parents of children ages 22 to 39 months who have been flagged by a special screening tool.
Wilmington, DelawareAges 18 years+ - NCT05703685RecruitingPhase 1
Imaging brain inflammation target in depression with PET
This Phase 1 study uses a PET brain scan tracer to see how a specific brain target (PDE4B) is involved in major depressive disorder (MDD). It’s mainly testing whether the imaging approach works and what it shows in people with depression who meet specific safety and medication rules.
Bethesda, MarylandAges 18–70 - NCT07131215Recruiting
Smart technology for health in early menopause
This trial tests whether a smartphone-based program can help monitor and improve the physical and mental health of women who have recently gone through menopause. It aims to see if technology can support healthy lifestyle changes during this transition.
TainanAges 40–65 - NCT07649733Recruiting
Virtual Reality Wellness Program for Healthcare Workers
This study tests whether using virtual reality can help healthcare workers reduce stress and improve well-being. You would attend weekly sessions using a VR headset designed to help you relax.
Badalona, BarcelonaAges 18 years+ - NCT07109245RecruitingPhase 4
Do antipsychotics block insulin action in the brain?
This study tests whether a single dose of a common antipsychotic medication affects how the brain responds to insulin, which could help explain weight gain and metabolic side effects. Healthy young adults will receive either the antipsychotic or a placebo, then have their brain activity measured with an MRI.
Toronto, OntarioAges 18–35 - NCT06385223Recruiting
Personalized brain stimulation for hard-to-treat depression
This study tests a new, personalized form of brain stimulation (called TMS) using MRI scans to target the right areas for people whose depression hasn't improved with medication. It aims to see if this tailored approach works better than standard TMS.
SingaporeAges 21 years+ - NCT06736522Recruiting
Youth leadership and mindfulness program for high school students
This study tests a program designed to build leadership skills, engagement, and mindfulness in high school students. If you're a teen in certain Massachusetts or Illinois schools, this program may help you grow personally and socially.
Chicago, IllinoisAges 14 years+ - NCT06619782Recruiting
Helping clinics support teens at risk for suicide
This study tests a way to help clinics better support teens and young adults who might be at risk for suicide. If you are 12 to 24 and your doctor's screening shows you may need extra help, the clinic will use a special program to connect you with the right care.
Aurora, ColoradoAges 12–80 - NCT07475039Recruiting
Friendly phone calls to support older adults
This study tests whether a program of friendly phone calls from trained volunteers can help older adults feel more connected and supported. If you are 65 or older and already receive home-delivered meals or other services, you may be able to join.
Gainesville, FloridaAges 55 years+ - NCT06997549Recruiting
Review of mental health treatment outcomes
This study looks back at information from a large database of people who received mental health treatments. It aims to understand how well treatments worked and what factors influenced outcomes.
Malvern, PennsylvaniaAges 5–100 - NCT07494110Recruiting
Aurora: AI storytelling for emotional wellbeing
This study tests a guided, AI-based storytelling tool to help people process their experiences and feel better emotionally. Depending on who you are, the session lasts 1 to 4 hours.
Barcelona, BarcelonaAges 18 years+ - NCT06484088RecruitingEarly Phase 1
Brain scanning study of frustration in healthy adults
This study looks at how the brain handles frustration in healthy adults using a special brain scanner called magnetoencephalography (MEG). It may help researchers understand normal brain responses to frustration.
Bethesda, MarylandAges 18–55 - NCT07485673Recruiting
Teens health and activity study
This study looks at the health and activity needs of teenagers in Ecuador. It involves answering questions about your lifestyle and may include physical activity. It's a chance to help researchers understand how to support teen health.
Quito, PichinchaAges 14–19 - NCT07481968Enrolling by invitation
Music mindfulness for children in the community
This study tests whether a fun, music-based mindfulness program in the community can help children manage emotions and improve well-being. It is for children ages 8 to 12 who are new to mindfulness.
Buffalo, New YorkAges 8–12
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Common questions
- Are there clinical trials for mental health?
- Yes. Clin2 currently lists 725 recruiting mental health studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a mental health trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a mental health trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.