Clinical trials
Ocular Surface Disease clinical trials
Below are recruiting ocular surface disease clinical trials, each written for real people, not researchers. We’re tracking 34 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06298890Recruiting
Dry eye pattern after cataract surgery
This study looks at how dry eye symptoms change after cataract surgery. It is for older adults (50–90) having simple cataract surgery for the first time, without other eye problems or certain health conditions.
KaunasAges 50–90 - NCT05797415Recruiting
Check sentinel lymph node biopsy for several eye skin cancers
This trial studies whether a “sentinel lymph node biopsy” can better detect cancer spread in people with specific cancers of the eye surface and nearby tissues. It may help doctors find the right next treatment by learning whether lymph nodes are involved.
Roma, RomeAges 18–95 - NCT07628946Recruiting
Eye Disease Database Study with Advanced Imaging
This study is building a detailed database of images and information from people with various eye diseases, especially those involving inflammation or swelling. Researchers will use advanced cameras and tests to better understand these conditions and potentially improve treatments.
BeijingAges 3 years+ - NCT07618364Recruiting
Rinsing to reduce eye inflammation in dry eye disease
This study tests whether rinsing the eye surface helps reduce inflammation and symptoms in people with dry eyes. Participants must have a specific inflammatory marker (MMP-9) in both eyes.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT07608367Recruiting
Hydrogel glue for eye surface repair surgery
This trial tests a new hydrogel glue that may replace stitches during eye surface repair surgery. It could help your eye heal faster and more comfortably after procedures like pterygium removal or corneal repair.
Jinan, ShandongAges 18–85 - NCT07537426Recruiting
Acupuncture for Dry Eyes After Facial Paralysis
This trial tests whether tiny acupuncture needles placed under the skin can help relieve dry eyes and other eye discomfort that develops after long-lasting facial paralysis. The goal is to see if this treatment can improve symptoms when standard care hasn't worked well enough.
Hangzhou, ZhejiangAges 18–65 - NCT07502378RecruitingPhase 4
Eye drops for dry eye in early neurotrophic keratopathy
This trial tests a new eye drop (acoltrepon) to see if it helps people with stage 1 neurotrophic keratopathy (a condition where the cornea's nerves are damaged, causing dry eyes and vision problems) and low tear production. It aims to improve signs like corneal staining and symptoms of discomfort.
Tampa, FloridaAges 18 years+ - NCT07732855Recruiting
Treating eye surface inflammation
This study tests a treatment for inflammation on the eye's surface, specifically keratitis (cornea inflammation), to see if it can help calm the redness, pain, or irritation.
Budapest, Pest CountyAges 4–60 - NCT06714799Recruiting
Skin lesion analysis study for eye and eyelid growths
This study looks at skin growths near the eye using a special camera. It may help doctors better understand and diagnose these growths without needing a biopsy.
BolognaAges 18 years+ - NCT04946721Recruiting
Study of eye-surface disease tests and targeted treatment
This study looks at how an “ocular surface” condition can be identified using tests (biomarkers) and how a targeted treatment may help. You may qualify if you’re an adult receiving eye care at specific University of Maryland locations.
Baltimore, MarylandAges 18 years+ - NCT07297849Recruiting
Eyelid closure effect on cornea measurement
This trial tests whether closing the eyelids changes the accuracy of a cornea measurement tool. It may help people whose cornea measurements are flagged as "warning" by the device.
Vienna, State of ViennaAges 18 years+ - NCT04354545Recruiting
Testing treatments for eye discomfort in glaucoma
This trial studies how to treat eye surface discomfort in people who have glaucoma and are already using multiple eye drops. It may help reduce symptoms like irritation while keeping glaucoma treatment on track.
Fountain Valley, CaliforniaAges Any age - NCT07796178RecruitingPhase 4
Dry eye relief and comfort after cataract surgery
This study tests a treatment called Lacrifill to see if it helps reduce dry eye symptoms after cataract surgery. You would receive the treatment after your surgery to see if it improves comfort and eye health.
Pittsburg, KansasAges 18–80 - NCT07510087Recruiting
Glaucoma and quality of life study
This study examines how glaucoma affects day-to-day life. It asks people with any type of glaucoma to complete a questionnaire about their quality of life.
Iowa City, IowaAges 18 years+ - NCT06780293RecruitingPhase 2
Laser acupuncture for dry eye and Sjogren's dry eye
This study tests if laser acupuncture can help people with dry eye symptoms, including those with Sjogren's syndrome, which causes dryness in the eyes and mouth. It may be a good fit if you have dry eye or Sjogren's and meet the age and eye test requirements.
Taipei, TaiwanAges 20–75 - NCT06919081RecruitingPhase 2
Stem cell eye drops for chronic cornea problems
This study tests whether a special substance from stem cells (called secretome) can help heal chronic surface problems on the eye that haven't gotten better with standard treatments. It's for people with a stubborn scratch or defect on the cornea that has lasted more than 14 days.
Chicago, IllinoisAges 18 years+ - NCT06984549Recruiting
Dry eye detection via smartphone camera
This study tests if a smartphone can take clear pictures and videos of your eyes to help doctors check for dry eye disease. It may be a simpler way to evaluate dryness from home.
Wenzhou, ZhejiangAges 18 years+ - NCT07776210RecruitingPhase 3
Eye drops for chronic dry eye after stem cell transplant
This trial tests an eye drop solution for people with chronic dry eye caused by graft-versus-host disease after a stem cell transplant. It aims to see if the drops can reduce eye discomfort and improve the eye surface.
Beverly Hills, CaliforniaAges 18 years+ - NCT04704648Recruiting
Surgery for a one-eye surface tumor in people with HIV
This study looks at whether removing a suspected pre-cancer/cancer growth on the surface of the eye can be done safely in people living with HIV. It is a feasibility (safety and practical) study, helping doctors refine the best surgical approach and follow-up.
KampalaAges 18 years+ - NCT07332988Enrolling by invitation
Light therapy for dry eyes in Graves' disease
This trial tests if low-level light therapy can improve dry eye symptoms in people with Graves' disease whose dry eyes haven't gotten better with standard treatments like artificial tears.
Iași, IaşiAges 18 years+ - NCT07605572Recruiting
GLP-1 drugs and dry eye disease in type 2 diabetes
This study tests whether a diabetes and weight-loss medication called GLP-1 receptor agonists affects dry eye disease. Researchers want to see if this medication helps or worsens dry eyes in people with type 2 diabetes and obesity.
AthensAges 18 years+ - NCT07363824Recruiting
Tear iron and dry eye severity study
This study looks at how iron levels in tears relate to the severity of dry eye disease. It aims to find a simple way to measure dry eye severity, which could help doctors better understand and treat the condition.
ShanghaiAges 18–70 - NCT07119580Recruiting
Glaucoma, eye surface health, and tear proteins
This study looks at how glaucoma and its treatments affect the surface of the eye and proteins in tears. It may help find better ways to manage eye health in people with glaucoma.
HsinchuAges 18 years+ - NCT04700657Recruiting
Study dryness patterns in eye graft-vs-host disease
This study looks at how common and how severe corneal nerve-related dryness is in people with chronic graft-vs-host disease (GVHD) after a stem cell transplant. It may help doctors understand which eye problems are most typical and how best to recognize them early.
Indianapolis, IndianaAges 18 years+
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Common questions
- Are there clinical trials for ocular surface disease?
- Yes. Clin2 currently lists 34 recruiting ocular surface disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a ocular surface disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a ocular surface disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.