Clinical trials
Ocular Hypertension clinical trials
Below are recruiting ocular hypertension clinical trials, each written for real people, not researchers. We’re tracking 34 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07588152RecruitingPhase 4
How Netarsudil Eye Drops Affect the Eye's Drain System
This study uses special imaging to see how the eye-pressure-lowering medication netarsudil (Rhopressa) works on the part of your eye that drains fluid. Researchers want to understand whether it helps restore normal drainage in people with high eye pressure or glaucoma.
Bloomington, IndianaAges 18 years+ - NCT06827535Enrolling by invitation
Long-term study of eye changes in glaucoma and high eye pressure
This study tracks changes in blood flow, structure, and vision over time in people with glaucoma or high eye pressure. It aims to understand how these conditions progress, which could help improve future treatment.
Milan, ItalyAges 18 years+ - NCT04401982RecruitingPhase 4
Testing eye drops for blood flow in high eye pressure and glaucoma
This study tests whether three different eye drop treatments (netarsudil, latanoprost, or both together) can improve blood flow to the white part of the eye and the retina. It may help people with high eye pressure or who are glaucoma suspects better understand how these treatments work.
Baltimore, MarylandAges 18 years+ - NCT07325240RecruitingPhase 4
Comparing Rocklatan and Latanoprost for eye pressure
This study compares a new combination eye drop (Rocklatan) to a standard one (Latanoprost) to see how well they control eye pressure over 24 hours. It may help people with open-angle glaucoma or high eye pressure find a more effective treatment.
Rochester, MinnesotaAges 18 years+ - NCT07036510RecruitingPhase 1/Phase 2
Safety and effectiveness of a timolol eye implant for glaucoma patients having cataract surgery
This trial tests a sustained-release implant that delivers timolol, a medicine to lower eye pressure, for people with glaucoma or high eye pressure who are also having cataract surgery. The implant is placed during surgery and may provide long-term pressure control without daily eye drops.
Panama CityAges 40 years+ - NCT07675824RecruitingPhase 1/Phase 2
New treatment for open-angle glaucoma or high eye pressure
This trial tests an investigational drug called REGN22530 for people with mild to moderate primary open-angle glaucoma or ocular hypertension (high eye pressure). The goal is to see if it can safely lower eye pressure and protect vision.
Deerfield Beach, FloridaAges 18 years+ - NCT07661329RecruitingPhase 3
Comparing a new eye drop to a standard one for glaucoma and high eye pressure
This study tests a new eye drop against an existing one to see which better lowers eye pressure in people with open-angle glaucoma or ocular hypertension. You may be able to join if you have high eye pressure in both eyes that needs treatment and you are at least 18 years old.
Beverly Hills, CaliforniaAges 18 years+ - NCT07662759RecruitingPhase 3
Study of TFC-003 for open-angle glaucoma or high eye pressure
This trial tests a new eye drop combination (TFC-003) to lower eye pressure in people with primary open-angle glaucoma or ocular hypertension. It compares the new drug to existing treatments to see if it works better or is safer.
SeongnamAges 19 years+ - NCT07335211RecruitingPhase 3
Testing a new eye drop for glaucoma or high eye pressure
This trial tests a new medicine called HUC3-637 for people with primary open-angle glaucoma or ocular hypertension. It aims to see if it safely lowers eye pressure.
SeoulAges 19 years+ - NCT05039684Recruiting
Testing eye-surface inflammation in glaucoma or high eye pressure
This study measures inflammation markers on the eye surface in people with primary open-angle glaucoma or ocular hypertension who use certain glaucoma drops. The results may help doctors understand how these drops affect the eye and inflammation.
ValladolidAges 18–99 - NCT05401357RecruitingPhase 3
Test eye drops for glaucoma or high eye pressure in both eyes
This Phase 3 study compares two versions of the same glaucoma eye-drop medicine (bimatoprost 0.01%) to see how similarly they work and their effect on eye pressure. It may help people with chronic open-angle glaucoma or ocular hypertension who need treatment in both eyes.
Newport Beach, CaliforniaAges 18 years+ - NCT07310719Recruiting
Comparing laser versus eye drops for new glaucoma patients
This trial compares two first treatments—laser therapy (SLT) or daily eye drops (latanoprost)—to lower eye pressure in people newly diagnosed with open-angle glaucoma or high eye pressure. It aims to find which approach works better as an initial therapy.
Ikeja, LagosAges 18–90 - NCT07119580Recruiting
Glaucoma, eye surface health, and tear proteins
This study looks at how glaucoma and its treatments affect the surface of the eye and proteins in tears. It may help find better ways to manage eye health in people with glaucoma.
HsinchuAges 18 years+ - NCT07217678RecruitingPhase 4
Eye drops and surface damage in glaucoma treatment
This study looks at how certain glaucoma eye drops affect the surface of your eye. It tests a new implant that may reduce damage and improve comfort.
Miami, FloridaAges 18 years+ - NCT05844384Recruiting
Testing a new eye drop bottle for glaucoma
This study checks whether a device called the Nanodropper helps deliver glaucoma medicine as well as standard use. It is for adults with stable primary open-angle glaucoma (or ocular hypertension) who are on a limited number of eye-pressure medicines.
Lackland Air Force Base, TexasAges 18 years+ - NCT04957329RecruitingPhase 4
Latanoprost eye drops: with or without preservative
This study compares two versions of latanoprost eye drops—one that contains a preservative and one that is preservative-free. It aims to see how each version affects the eye’s “goblet cells,” which help keep the eye surface healthy.
Glostrup Municipality, DanmarkAges 18 years+ - NCT07816692Recruiting
iDose implant for open-angle glaucoma
This study tests a tiny implant, called iDose, that is placed in the eye during a short office procedure to help lower eye pressure in people with open-angle glaucoma or high pressure in the eye (ocular hypertension). It may offer a way to manage pressure without daily eye drops.
Austin, TexasAges 18 years+ - NCT06691555Recruiting
Long-term safety of a silicone tube eye implant
This study follows up with people who have previously received a special silicone tube implant in their eye to see how they are doing over time. It aims to check the long-term safety and how well the implant is working.
TbilisiAges 40–90 - NCT07408154Recruiting
Direct vs standard laser for glaucoma: which works better?
This study compares a direct laser treatment to the standard laser for glaucoma or high eye pressure. It aims to see if the direct method is just as effective and possibly safer.
Charleston, South CarolinaAges 18 years+ - NCT07400926Recruiting
Study of a new inserter for a glaucoma implant
This trial is testing a new way to deliver a medication (travoprost) directly into the eye using a small implant. It's for people with open-angle glaucoma and aims to see how well the updated inserter works.
Kenosha, WisconsinAges 18 years+ - NCT07390890Recruiting
DSLT to reduce glaucoma eye drops
This trial is testing a laser treatment called DSLT to see if it can help people with glaucoma use fewer eye drops. It may be a good option if your eye pressure is already controlled with medication and you haven't had glaucoma surgery before.
Largo, FloridaAges Any age - NCT07218783RecruitingPhase 3
Testing a new glaucoma implant with cataract surgery
This trial tests a new implant that releases medicine for glaucoma while you have cataract surgery. It may help lower eye pressure without using daily drops.
Houston, TexasAges 22 years+ - NCT07218796RecruitingPhase 3
Bimatoprost implant with IOL vs. timolol drops for glaucoma
This trial tests if a bimatoprost implant placed during cataract surgery (combined with a special lens) can lower eye pressure better than standard timolol eye drops. It may help people with mild to moderate glaucoma or high eye pressure who are already planning cataract surgery.
San Antonio, TexasAges 22 years+ - NCT07206628Recruiting
Glaucoma eye drop adherence with easygrip bottle
This study looks at how well people stick to their glaucoma eye drop routine when using a special bottle called EASYGRIP®. If you use this type of bottle for your glaucoma drops, this study may help doctors understand how to make treatment easier.
BolognaAges 18 years+
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Ocular Hypertension trials by city
Studies with a site in or near these metro areas.
Ocular Hypertension trials by state
Studies with a site anywhere in these states.
Common questions
- Are there clinical trials for ocular hypertension?
- Yes. Clin2 currently lists 34 recruiting ocular hypertension studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a ocular hypertension trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a ocular hypertension trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.