Clinical trials
Opioid Overdose clinical trials
Below are recruiting opioid overdose clinical trials, each written for real people, not researchers. We’re tracking 15 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06806163Recruiting
Preventing Opioid Overdoses with Smart Reminders
This study tests whether a computer program can help doctors and patients have a conversation about safe opioid use. It uses information from your medical records to send reminders to your doctor, aiming to prevent overdoses.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT07079241Recruiting
Volunteer naloxone responders for opioid overdose emergencies
This trial trains volunteers to give naloxone, a medication that reverses opioid overdoses, using a smartphone app to alert nearby responders. It could help save lives by getting antidote treatment to overdose victims faster.
Malmö, Skåne CountyAges 18 years+ - NCT04811014RecruitingPhase 4
Helping young adults stop opioids after an emergency visit
This study offers an engagement program for young people who tested positive for opioids and meet criteria for opioid dependence. The goal is to help participants stop opioid use safely and learn whether this approach works well in the real-world emergency setting.
Houston, TexasAges 13–17 - NCT06466005Recruiting
Phone app to help reverse overdoses in Philadelphia
This trial tests a smartphone app that helps people quickly reverse an opioid overdose. If you live or work in certain Philadelphia neighborhoods, the app may help you save a life.
Philadelphia, PennsylvaniaAges 18 years+ - NCT07631598Recruiting
Buprenorphine at Needle Exchange Programs to Prevent Overdoses
This study tests whether offering buprenorphine (a medication that reduces cravings and withdrawal) directly at syringe service programs (places where people get clean needles) can help people with opioid addiction stay safe and reduce overdose risk. If you use opioids and visit a syringe service program, this may be an option to explore.
Los Angeles, CaliforniaAges 18 years+ - NCT05877118Recruiting
Helping people get naloxone education at ED discharge
This trial tests ways to improve how people receive naloxone (an emergency overdose-reversal medicine) education when they leave the emergency department with a prescription kit. It may help patients and caregivers feel more confident using naloxone during an overdose emergency.
Hartford, ConnecticutAges 21–65 - NCT06593093RecruitingPhase 1/Phase 2
Continuing buprenorphine after an overdose emergency
This study tests a bundled approach to help adults who have had an opioid overdose and are starting buprenorphine in the emergency department continue their recovery after being discharged. It is for people who want to stay on buprenorphine and need support after leaving the hospital.
Birmingham, AlabamaAges 19 years+ - NCT06823453Recruiting
Training friends and family to support people who use opioids
This study trains friends and family members of people who use opioids, so they can provide better support and reduce stigma. It also includes people who use opioids to see if this training improves their relationship and well-being.
Chicago, IllinoisAges 18 years+ - NCT07179614Recruiting
Kentucky women's overdose recovery program
This trial tests a support program for women in Kentucky jails who have opioid or stimulant use disorder. It aims to reduce overdose risk after release by connecting them with community support.
Harlan, KentuckyAges 18 years+ - NCT06316830RecruitingPhase 2/Phase 3
Finding the best buprenorphine dose for opioid use disorder
This trial tests different doses of buprenorphine to find the safest and most effective one for treating opioid use disorder and preventing overdose. It is for people who have used fentanyl and are starting or continuing buprenorphine treatment.
Providence, Rhode IslandAges 18 years+ - NCT06573476Recruiting
Smartphone app and peer coach for opioid treatment
This study tests whether a smartphone app and support from a peer recovery coach can help Black and Latinx individuals with opioid use disorder start buprenorphine treatment. The goal is to reduce overdose deaths and address racial gaps in care.
New York, New YorkAges 18–99 - NCT06320015Recruiting
Peer support for recovery after an emergency visit
This trial tests whether a peer recovery worker can help adults who came to the emergency room for a drug- or alcohol-related problem stay engaged in recovery. If you join, you'll get extra support from someone who has been through similar experiences.
Providence, Rhode IslandAges 18 years+ - NCT06084221Enrolling by invitation
Studying overdose review teams to improve surveillance
This study looks at how local overdose fatality review (OFR) teams work and how they can help track and prevent overdoses better. Researchers will also use anonymous administrative data to understand overdose patterns in Indiana. The goal is to make our surveillance systems stronger and save lives.
Indianapolis, IndianaAges Any age - NCT05665179Recruiting
Community program for people receiving addiction treatment
This trial is focused on people who are currently getting treatment for substance use disorder. It aims to test community partnership approaches that reduce barriers and improve support during recovery.
Ann Arbor, MichiganAges 18 years+ - NCT06768814Recruiting
Overdose recovery and care access study
This study looks at how people recover from an overdose and get connected to care. It interviews people who have had an overdose to understand their experience and improve access to follow-up services.
Seattle, WashingtonAges 18 years+
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Common questions
- Are there clinical trials for opioid overdose?
- Yes. Clin2 currently lists 15 recruiting opioid overdose studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a opioid overdose trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a opioid overdose trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.