Clinical trials
Palliative Care clinical trials
Below are recruiting palliative care clinical trials, each written for real people, not researchers. We’re tracking 102 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07063862RecruitingPhase 3
Psychedelic microdose for emotional distress in advanced illness
This trial tests whether very low doses of psilocybin (a psychedelic substance) can help reduce emotional distress in people with a life-limiting illness. If you are receiving palliative care and feeling anxious or depressed, this study might offer a way to explore a new treatment option.
Brampton, OntarioAges 18 years+ - NCT06886529Recruiting
Patient and family involvement in cardiology care at SickKids
This study looks at how patients and families can be more involved in care for children admitted to the cardiology unit at SickKids. It may help improve how the hospital works with families.
TorontoAges Up to 18 years - NCT06615349Recruiting
Digital monitoring for palliative care patients
This trial tests whether using a smartphone app to track your symptoms and health data can improve care and quality of life for people with serious illnesses who are receiving palliative care.
Zurich, Canton of ZurichAges 18 years+ - NCT05403086RecruitingPhase 2
Psilocybin for distress in people with serious, life-limiting illness
This Phase 2 study tests whether psilocybin therapy can reduce deep distress (“demoralization”) in people receiving palliative (comfort-focused) care. It may help with mood and well-being, but you must meet safety and medication requirements to join.
Greenbrae, CaliforniaAges 18 years+ - NCT06097533RecruitingPhase 2
Cannabinoids to improve quality of life in cancer patients
This trial tests if a cannabinoid (a compound from the cannabis plant) can improve quality of life and reduce pain in people receiving palliative cancer care. It is for patients who have moderate to severe symptoms like pain and nutrition problems.
Hamburg, Free and Hanseatic City of HamburgAges 25 years+ - NCT05894694RecruitingPhase 4
Testing Compound Kushen injection for advanced colon cancer survival
This trial studies whether Compound Kushen injection can improve survival in people with advanced colorectal cancer. It’s aimed at people starting first-line treatment, and only includes certain cancer and health situations to keep results clear.
BeijingAges 18 years+ - NCT05754801RecruitingPhase 2
Yunzhi essence for quality of life in advanced cancer
This Phase 2 trial tests whether Yunzhi essence (a traditional Chinese medicine) can improve quality of life for people with advanced cancer. It also requires certain screening results about life expectancy, thinking/alertness, and symptom pattern.
Hong KongAges 21–89 - NCT03333200Recruiting
Study of genetic brain diseases over time
This trial follows people with genetic neurodegenerative (brain-wasting) disorders over time to better understand how the condition changes. The goal is to learn patterns that could help future treatments or care plans.
Pittsburgh, PennsylvaniaAges Any age - NCT04824144RecruitingPhase 1/Phase 2
Dexmedetomidine for agitation in palliative care delirium
This trial tests whether dexmedetomidine can help calm agitation caused by delirium in adults receiving palliative (comfort-focused) care. It may help reduce restlessness and distress when standard approaches may not be enough.
Calgary, AlbertaAges 18 years+ - NCT04984551RecruitingPhase 2
Training plus support to improve palliative care for advanced cancer
This trial studies whether a program called Project ECHO can improve the quality of palliative care (comfort-focused care) for people with advanced cancer and their caregivers in underserved areas. It also involves training local health care providers so they can better support patients and families over time.
Houston, TexasAges Any age - NCT05306509Recruiting
Early palliative care talks for kids with cancer
This trial tests whether nurse-led conversations about comfort and support (palliative care) early in a child’s cancer journey can help families and the child cope better. It is focused on newly diagnosed or relapsed pediatric cancer patients in Chinese-speaking settings.
Shanghai, MinhangAges Up to 18 years - NCT05998330Recruiting
Palliative care support for advanced liver disease patients
This study tests whether adding palliative care (extra support for symptoms and planning) during a hospital stay helps people with advanced liver disease and their caregivers feel better and plan ahead.
Boston, MassachusettsAges 18 years+ - NCT06044441Recruiting
Proactive palliative support for advanced cancer
This study offers a proactive program of support and education for people with advanced cancer and their caregivers. It aims to improve quality of life by starting palliative care conversations early, even before symptoms get worse.
SingaporeAges 21–120 - NCT06193083Recruiting
Deprescribing views of patients with advanced cancer
This study asks patients with advanced cancer about their thoughts on stopping medications that may no longer be needed or could be harmful. It aims to understand patient perspectives to improve care.
La Roche-sur-YonAges 18 years+ - NCT06266611RecruitingPhase 2
Cannabis for cancer symptom relief
This trial tests whether cannabis can help cancer patients manage symptoms like sleep trouble, pain, and mood changes. It's for people who are new to using cannabis for these issues.
Aurora, ColoradoAges 25 years+ - NCT06682936Recruiting
Outpatient talc procedure for cancer-related fluid buildup
This trial tests whether a talc procedure to seal the lung (pleurodesis) can be done safely in an outpatient setting for people with fluid buildup from cancer. It aims to make the treatment more convenient.
Stockton-on-Tees, County DurhamAges 18 years+ - NCT05466123Enrolling by invitation
Virtual reality experience for people near the end of life
This trial is testing a virtual reality (“VR”) experience for people who are nearing the end of life and already receiving comfort-focused care. It may help you and your care team understand whether VR can improve comfort, feelings, or quality of life during this time.
Jacksonville, FloridaAges 18 years+ - NCT06771999Recruiting
Deprescribing medications in cancer patients: a pharmacist's help
This trial tests whether a clinical pharmacist's educational session can help you and your doctor safely reduce or stop unneeded medications. It's for people receiving palliative care for cancer.
Baia Mare, MaramureşAges 18 years+ - NCT07039994Recruiting
Early palliative care for advanced lung cancer using an e-health system
This study tests whether an online platform can help deliver early palliative care to people with advanced lung cancer. The goal is to see if this approach can improve quality of life and manage symptoms from the start of treatment.
Badalona, BarcelonaAges 18 years+ - NCT07356843Recruiting
Palliative Care for Heart Failure Patients
This study looks at how to improve palliative care for people with heart failure. It involves healthcare workers who care for heart failure patients and will help find better ways to support them.
Indianapolis, IndianaAges 18 years+ - NCT00804154RecruitingPhase 1
Capsaicin-like drug for severe cancer pain
This Phase 1 trial tests a new drug related to capsaicin (resiniferatoxin) to reduce severe nerve pain from advanced cancer. It is given through a small catheter near the spinal fluid space and is meant for people whose pain medicines and other options have not worked well enough.
Bethesda, MarylandAges 18–99 - NCT02799537Recruiting
Compare a new end-of-life letter to advance directives
This study compares two ways of sharing your end-of-life wishes: a “Stanford Letter Project” form versus traditional advance directives. If you’re an adult, your answers may help the researchers see which option is easier to use or better understood.
Stanford, CaliforniaAges 18 years+ - NCT07552935Recruiting
High-Flow Oxygen for Breathing Difficulty in Palliative Care
This study tests whether high-flow nasal therapy (a special oxygen delivery method) can ease severe shortness of breath in patients receiving palliative care. Palliative care focuses on comfort when curative treatment is no longer the goal.
TampereAges 18 years+ - NCT06924268Enrolling by invitation
Art therapy for mood and symptoms in palliative care
This trial tests whether a single art therapy session can improve mood and reduce symptom burden for patients in a palliative care unit. It aims to see if creative expression can help you feel better emotionally and physically.
Halifax, Nova ScotiaAges 18 years+
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Common questions
- Are there clinical trials for palliative care?
- Yes. Clin2 currently lists 102 recruiting palliative care studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a palliative care trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a palliative care trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.