Clinical trials
Pediatric Cancer clinical trials
Below are recruiting pediatric cancer clinical trials, each written for real people, not researchers. We’re tracking 149 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05468359RecruitingPhase 1/Phase 2
Testing four medicines in children and teens with hard-to-treat tumors
This early-phase trial studies how safe and effective a combination of four medicines is for children and teens with certain solid tumors that have come back or cannot be controlled with standard treatment. It may help by improving tumor control, while also carefully tracking side effects.
Germantown, TennesseeAges Up to 30 years - NCT04134559RecruitingPhase 2
Pembrolizumab for kids with liver cancer that came back
This trial studies pembrolizumab (an immune therapy) in children and young people with hepatocellular carcinoma (HCC) that has returned or did not respond to earlier treatment. The goal is to see whether it can shrink tumors and help control the cancer.
San Francisco, CaliforniaAges birth–30 years - NCT04956133Recruiting
Physical activity program for kids during cancer treatment
This trial tests whether a structured physical activity program can help children and teens feel better and stay active during cancer treatment or shortly after. It involves the child and a parent/caregiver for safety during sessions.
Calgary, AlbertaAges 5–18 - NCT05294302Recruiting
Online support program for cancer parents in English or Spanish
This trial tests an online (e-health) counseling and support program for parents of children with cancer. It may help you feel better supported and more informed while caring for your child.
Los Angeles, CaliforniaAges Any age - NCT05524610Recruiting
Screening plan for sexual health in young cancer survivors
This study tests a new way to screen for sexual problems in teens and young adults (ages 15–24) who have had childhood cancer. The goal is to better spot issues and improve care during survivorship.
Aurora, ColoradoAges 15–24 - NCT06820294Enrolling by invitation
Genome sequencing study for children and young people with cancer
This study looks at whole genome sequencing (a complete read of your DNA) from children and young people with cancer. It aims to learn more about cancer and how it might be treated.
CambridgeAges birth–21 years - NCT07403630Recruiting
Tumor chemogenomic profiler for cancer patients of all ages
This trial uses a new testing platform to analyze the genes and proteins in your tumor, aiming to find the most effective treatments for people with cancer that has come back, is not responding to treatment, or has spread. It is designed for both children and adults with any type of blood cancer or solid tumor.
Palermo, PalermoAges 1 year+ - NCT06674811Recruiting
Childhood cancer surgery recovery study
This study looks at how children and young adults recover after surgery for solid tumors. It also includes their caregivers to understand how resilience affects recovery.
Rochester, MinnesotaAges 3–25 - NCT06786104Recruiting
Video talks about ethical choices for kids with cancer
This trial uses videos to help parents and doctors discuss tough ethical decisions for children with cancer. It aims to guide conversations about treatment goals and care options.
Birmingham, AlabamaAges Any age - NCT06939322Recruiting
Long-term monitoring app for childhood cancer survivors
This trial tests whether a special software (LOG-AFTER) helps people who had cancer before age 25 keep up with long-term screenings. It aims to make follow-up care easier and more consistent.
Angers, Maine Et LoireAges 15 years+ - NCT07444216Recruiting
A study on hope in teens and young adults with advanced cancer
This study explores hope in patients aged 12-25 with pediatric cancer that has returned, not responded to treatment, or has no cure. Participants take photos and share their stories to help doctors and families understand what hope means during early-phase clinical trials (phase 1 or 2).
Memphis, TennesseeAges 12 years+ - NCT06905587RecruitingPhase 3
Methylphenidate for fatigue in young brain tumor survivors
This trial tests whether the medicine methylphenidate (often used for ADHD) can help reduce severe fatigue in children and teens who have finished treatment for a brain tumor. If you're a young brain tumor survivor struggling with ongoing tiredness, this study may offer a new option.
AalborgAges 6–27 - NCT06612645RecruitingPhase 1
CAR T cell therapy for children with solid tumors that returned
This trial tests a new type of immune therapy called CAR T cells designed to find and attack a protein called B7-H3 on solid tumor cells. It's for children and young adults whose cancer came back or didn't respond to standard treatment.
Bangkok, PathumwanAges 1–25 - NCT07680439RecruitingPhase 2
CAR T cell therapy study for children with DIPG brain tumor
This trial tests a new CAR T cell therapy (BCB-276) for children and young adults with a type of brain tumor called DIPG. The therapy uses your own immune cells that are specially trained to attack the cancer.
Los Angeles, CaliforniaAges 1–26 - NCT03315546RecruitingPhase 1/Phase 2
Breathing-hold radiotherapy for children with chest or belly tumors
This early-phase trial tests a radiotherapy technique that uses deep, coached breaths and short breath-holds to help protect healthy organs during treatment. It may help children who need radiation for certain tumors in the chest or belly area.
Copenhagen, DanmarkAges 5–17 - NCT06858163Recruiting
Coping and attachment in pediatric cancer
This study looks at how parents and children cope with pediatric cancer. It involves questionnaires for both you and your child, and aims to understand how your relationship affects coping.
Monza, Monza-BrianzaAges 8–17 - NCT03435042Recruiting
Hypnosis group program to help children with cancer and parents
This trial tests a hypnosis-based group program to improve quality of life for children with cancer and their parents. You may join if your family speaks French and the child is aged 8–18 and has cancer (or has a sibling with cancer).
LiègeAges 8 years+ - NCT04511806Recruiting
Study of inherited cancer risk in children and families
This study looks at how inherited “cancer predisposition” conditions run in families, even if a child has not had cancer yet. It may help doctors better understand who is at higher risk and guide future monitoring or care.
Atlanta, GeorgiaAges Any age - NCT05058508Recruiting
Exercise program for children and young adults on new cancer treatment
This study tests an exercise program for young people newly diagnosed with cancer who are starting treatment like chemotherapy. It aims to see whether safely adding exercise can be part of care during the first treatment cycles.
Charlotte, North CarolinaAges 2–25 - NCT05383092Recruiting
Exercise program for kids with cancer and healthy insulin
This trial studies an adapted exercise (physical activity) program for children starting treatment for cancer to see if it can improve insulin sensitivity. It may help kids feel better and support healthy body metabolism during treatment.
ToulouseAges 5–18 - NCT06033183Recruiting
Study of radiation sensitivity in children with cancer
This study looks at how children's bodies respond to radiation therapy for certain cancers. By analyzing blood samples, researchers hope to learn why some children experience more side effects, which could help personalize future treatments.
CaenAges 3–18 - NCT07288476Recruiting
Spanish videos for parents of kids with cancer
This study creates and tests Spanish educational videos for parents of children with cancer. It aims to help Spanish-speaking families better understand their child's cancer care.
Aurora, ColoradoAges 18 years+ - NCT07537062Recruiting
Virtual Reality to Reduce Anxiety During Cancer Chemotherapy in Children
This study tests whether wearing virtual reality headsets can help reduce anxiety and fear in children with cancer who need a spinal injection of chemotherapy (a needle procedure into the spine). The goal is to see if this distraction tool makes the experience less stressful for kids and their families.
KayseriAges 4–10 - NCT06763770Enrolling by invitation
Digital support for young adult cancer survivors
This trial tests a digital program that combines self-management tools and peer mentoring to help young adults who had childhood cancer transition to long-term follow-up care.
Los Angeles, CaliforniaAges 18–25
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Common questions
- Are there clinical trials for pediatric cancer?
- Yes. Clin2 currently lists 149 recruiting pediatric cancer studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a pediatric cancer trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a pediatric cancer trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Beyond the search
We also like to point to nonprofits doing real good in this area. We aren’t affiliated with them — we just admire the work.
- Children’s Oncology Support FundChildren with cancer and the families caring for them.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.