Clinical trials · Indiana
Phenylketonuria clinical trials in Indiana
We’re tracking 6 recruiting phenylketonuria studies with a site in Indiana — including Phase 1, Phase 2, Phase 3 and Phase 4 studies, each written for real people, not researchers.
Recruiting studies in Indiana
- NCT07241234RecruitingPhase 1
Study of an experimental drug for phenylketonuria (PKU)
This trial tests an investigational drug (AG-181) for people with PKU who have a specific genetic change (R408W mutation). It aims to check if the drug is safe and how it works in your body.
Indianapolis, IndianaAges 18–69 - NCT06302348RecruitingPhase 3
Sepiapterin study for phenylketonuria
This study tests a new medicine called sepiapterin to see if it can help control blood phenylalanine levels in people with PKU. The trial aims to find a safe and effective dose for different age groups.
Indianapolis, IndianaAges Up to 9 years - NCT07694440RecruitingPhase 2
Study of an experimental pill for adults with PKU
This trial tests an experimental medication taken as a pill to see if it can help people with PKU manage their condition. The study will check if the pill is safe and how it affects blood phenylalanine levels.
Indianapolis, IndianaAges 18–75 - NCT07477691RecruitingPhase 4
Immune therapy during Palynziq treatment for PKU
This study tests whether combining a drug called methotrexate with Palynziq (a treatment for PKU) can help control immune responses and improve treatment outcomes. It may be an option for adults with PKU who have never used Palynziq or who have not reached target blood levels after at least 24 weeks.
Indianapolis, IndianaAges 18–65 - NCT06305234Recruiting
Long-term immune response study for Palynziq PKU treatment
This long-term study checks how the immune system reacts to Palynziq (a treatment for PKU) over time. It involves extra blood tests for people already in another PKU study called 165-501.
Indianapolis, IndianaAges Any age - NCT05813678Recruiting
Long-term safety monitoring for Palynziq in PKU
This study tracks the long-term safety of Palynziq (pegvaliase) in people with PKU as they take the medicine over time. It may help you and other patients understand long-term side effects and whether Palynziq stays safe.
Indianapolis, IndianaAges Any age
Phenylketonuria trials by city in Indiana
Where these studies are running in Indiana
Institutions with a site for the recruiting phenylketonuria studies listed above.
- Indiana University School of Medicine · 4 studies
- Indiana University
- Riley Children's Hospital/ Indiana University Health
What taking part in a phenylketonuria study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Phenylketonuria trials in other states
Common questions
- Are there phenylketonuria clinical trials in Indiana?
- Yes. We're currently tracking 6 recruiting phenylketonuria studies with a site in Indiana, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a phenylketonuria study in Indiana?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Indiana to take part?
- Not necessarily. These studies have a site in Indiana, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a phenylketonuria trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New phenylketonuria studies open in Indiana regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.