Clinical trials
Postoperative Depression clinical trials
Below are recruiting postoperative depression clinical trials, each written for real people, not researchers. We’re tracking 14 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07227389Recruiting
Opioid Timing and Breathing Risk After Surgery
This study looks at when opioids are given during surgery and how it affects breathing problems after surgery. It might help understand how to make pain control safer.
Detroit, MichiganAges 18–85 - NCT07464860Recruiting
Breathwork for older adults after knee surgery
This study tests a breathing exercise program to help older adults recover after knee replacement surgery. Participants practice controlled breathing at home using a smartphone or computer.
Tucson, ArizonaAges 65 years+ - NCT06777758RecruitingPhase 4
Comparing two sedatives for endoscopy procedures
This trial compares two sedative medications, Remimazolam and Propofol, to see which works better for upper GI endoscopy exams and treatments. The goal is to help doctors choose the best option for patients.
Kaohsiung CityAges 20–80 - NCT07573150Recruiting
Pupil Measurements to Predict Breathing Problems After Surgery in Children
This study tests whether measuring how a child's pupils (the dark circles in the eyes) respond to light can predict which children might have breathing problems after receiving pain medication during tonsil surgery. The goal is to help doctors catch and prevent serious breathing issues before they happen.
San Francisco, CaliforniaAges 3–17 - NCT06221280Enrolling by invitation
Nerve blocks for pain after cesarean and depression
This study tests whether a nerve block (extra numbing medicine) given during a cesarean section can help with pain after delivery and may reduce the risk of postpartum depression. The trial compares the nerve block to standard care.
Kahramanmaraş, KahramanmaraşAges 18 years+ - NCT04303325RecruitingPhase 4
Esketamine after breast surgery for depression and gut changes
This trial studies whether esketamine given around the time of breast cancer surgery can improve depression and change gut bacteria. It also monitors your sleep/deep anesthesia level (with a simple monitoring number).
Shenyang, LiaoningAges 18–65 - NCT05400382Recruiting
Mindfulness for depression and pain after cesarean delivery
This study tests whether a mindfulness program can help new mothers manage pain and depression after a planned cesarean delivery. You might be eligible if you are a woman of color or non-Hispanic White with a history of depression and are scheduled for a planned C-section.
Champaign, IllinoisAges 18–45 - NCT05379673Recruiting
Breathing changes with extra oxygen after surgery
This study looks at whether giving extra oxygen during recovery from general anesthesia changes how you breathe after surgery. You may be offered different oxygen levels around the time you wake up to see what helps your breathing most comfortably.
Stanford, CaliforniaAges 18–70 - NCT07454070Recruiting
Testing ear nerve stimulation for depression after a heart attack
This trial tests if a gentle, non-invasive ear stimulation device can help relieve depression in people who have had a heart attack and a stent placed. It aims to offer a drug-free option for those who choose not to take antidepressants or see a therapist.
Xi'an, ShaanxiAges 18 years+ - NCT06903819RecruitingPhase 4
Ketamine for pain and mental health after orthopedic injury
This trial tests if ketamine can reduce pain, opioid use, and improve mental health in adults recovering from serious orthopedic injuries. It may help those with high injury severity scores.
Lubbock, TexasAges 18–65 - NCT07604389Recruiting
Augmented Reality Video for Breast Cancer Recovery
This study tests whether an interactive video using augmented reality (a technology that overlays digital information on the real world) helps breast cancer patients recover better after surgery. Researchers want to see if this educational tool improves your understanding of your condition and recovery process.
Taichung, Taichung CityAges 18 years+ - NCT06706323Recruiting
Depression after heart surgery study
This study looks at depressive symptoms in people who have had heart bypass surgery. It aims to understand how patients feel emotionally after surgery and may help improve care.
ZurichAges 18–90 - NCT06687291Recruiting
Thinking and memory after stomach or esophagus cancer surgery
This study looks at how surgery and chemotherapy for stomach or esophageal cancer may affect your thinking, memory, and other cognitive functions. Researchers want to understand these changes to better support patients.
HuddingeAges 18 years+ - NCT06221020Recruiting
Enhanced recovery after pituitary tumor surgery
This study tests a standard care plan to help patients recover faster after surgery to remove a pituitary tumor. It may reduce hospital stay and improve recovery.
Kaohsiung CityAges 20–75
Hear when a new Postoperative Depression trial opens
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Common questions
- Are there clinical trials for postoperative depression?
- Yes. Clin2 currently lists 14 recruiting postoperative depression studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a postoperative depression trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a postoperative depression trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.