Clinical trials · California
Psoriasis clinical trials in California
We’re tracking 20 recruiting psoriasis studies with a site in California — including Phase 1, Phase 2, Phase 3 and Phase 4 studies, each written for real people, not researchers.
Recruiting studies in California
- NCT07116967RecruitingPhase 3
Long-term safety of two psoriasis drugs in people with heart risk
This study compares two medications for psoriasis (deucravacitinib and ustekinumab) over a long period. It's designed for people with moderate-to-severe psoriasis who also have certain risk factors for heart disease, like high blood pressure or diabetes.
Encinitas, CaliforniaAges 40 years+ - NCT06979453RecruitingPhase 3
A study of deucravacitinib for teens with plaque psoriasis
This trial tests an investigational oral medication called deucravacitinib for teenagers (adolescents) with moderate to severe plaque psoriasis. It aims to see if the drug is safe and works well.
Fountain Valley, CaliforniaAges 12–17 - NCT07474792RecruitingPhase 2
Study of ORKA-002 for moderate-to-severe plaque psoriasis
This trial tests an investigational drug called ORKA-002 for people with moderate-to-severe plaque psoriasis. It aims to see how well different doses work and if they are safe. You may qualify if your psoriasis covers at least 10% of your body or if it has not responded well enough to other treatments.
Fountain Valley, CaliforniaAges 18–79 - NCT07449702RecruitingPhase 2
Long-term safety study of ORKA-001 for plaque psoriasis
This study is a continuation for people who already took ORKA-001 for plaque psoriasis and did well. It tests whether staying on the medicine keeps helping without any new safety concerns.
Fountain Valley, CaliforniaAges 18 years+ - NCT07250802RecruitingPhase 3
Long-term study of zasocitinib for children with plaque psoriasis
This trial tests a daily pill (zasocitinib) for children and teens with moderate to severe plaque psoriasis that hasn't been controlled by other treatments. It aims to see if the pill can safely improve skin symptoms over a long period.
Chula Vista, CaliforniaAges 4–17 - NCT07390487Recruiting
Audio therapy for anxiety in people with psoriasis
This study tests whether listening to a short audio program (about 25–30 minutes) at home can help reduce anxiety in people with psoriasis. If you have psoriasis and have been feeling anxious, you may be able to take part from home using your computer or phone.
San Francisco, CaliforniaAges 18 years+ - NCT03987763RecruitingPhase 4
Study of psoriasis lotion safety in children ages 6–16
This trial tests how safe and how the body handles (pharmacokinetics) a psoriasis lotion called IDP-122 when used in children with plaque psoriasis. You may be able to join if your child has a suitable amount of plaque psoriasis and can follow safety rules during the study.
Fountain Valley, CaliforniaAges 6–17 - NCT07489885RecruitingPhase 2
Study of D-2570 for moderate to severe plaque psoriasis
This trial tests an experimental drug, D-2570, for people with moderate to severe plaque psoriasis. It aims to see if the medication can safely improve skin symptoms.
Chula Vista, CaliforniaAges 18–70 - NCT06574178Recruiting
Testing if a healthy diet reduces inflammation in psoriasis
This study uses a full-body PET scan to see if switching to a balanced, nutritious diet can lower inflammation throughout the body and in the skin for people with psoriasis. It may help if you are overweight and have a poor diet.
Sacramento, CaliforniaAges 18 years+ - NCT07362017RecruitingPhase 3
Ponesimod for moderate to severe plaque psoriasis
This trial tests an investigational drug called ponesimod for people with moderate to severe plaque psoriasis. It aims to see if the drug is safe and effective at improving skin symptoms.
Fremont, CaliforniaAges 18–65 - NCT05390515RecruitingPhase 4
Study immune response in adults with psoriasis on tildrakizumab
This trial studies how the immune system responds in adults with moderate-to-severe psoriasis when receiving tildrakizumab. The goal is to better understand treatment effects and immune changes, which may help improve care for people with psoriasis.
San Francisco, CaliforniaAges 18–75 - NCT05858632RecruitingPhase 4
Study immune patterns during guselkumab skin response in psoriasis
This trial studies how the immune system changes in the skin after guselkumab treatment for psoriasis, including the scalp. You may be asked to meet certain scalp severity and medication safety rules.
San Francisco, CaliforniaAges 18 years+ - NCT05858645RecruitingPhase 4
Deucravacitinib to correct immune signals in psoriasis
This Phase 4 study tests whether deucravacitinib can improve psoriasis by correcting abnormal immune-cell signals seen in people with moderate-to-severe disease. It may help reduce symptoms and improve control of psoriasis, while researchers also track immune changes.
San Francisco, CaliforniaAges 18–75 - NCT06888193RecruitingPhase 1
Bimekizumab in breast milk of mothers being treated
This study measures how much bimekizumab (Bimzelx) gets into breast milk. It helps us understand if the medicine is safe for breastfeeding babies whose mothers take this drug.
Santa Monica, CaliforniaAges 18 years+ - NCT03816345RecruitingPhase 1
Nivolumab for advanced cancer with autoimmune conditions
This Phase 1 study tests nivolumab, an immunotherapy “anti-cancer accelerator,” in people with advanced cancer who also have an autoimmune disorder. It aims to see if nivolumab can be given safely and whether it may help shrink or control cancer.
Palo Alto, CaliforniaAges 18 years+ - NCT06846710RecruitingPhase 1
Testing HS-20118 in healthy adults and psoriasis patients
This study tests a new medicine called HS-20118 in two parts: one in healthy adults to see how the body handles a single dose, and another in people with chronic plaque psoriasis to see how it works over multiple doses. It helps find a safe dose and shows whether it might reduce psoriasis symptoms.
Anaheim, CaliforniaAges 18–65 - NCT06857942RecruitingPhase 4
Tirzepatide added to ixekizumab for psoriasis and weight issues
This trial tests whether adding tirzepatide (a weight-loss and diabetes drug) to ixekizumab (a psoriasis treatment) helps people with moderate-to-severe psoriasis who are overweight or have obesity. It is for those already taking ixekizumab for about 3 months.
Los Angeles, CaliforniaAges 18 years+ - NCT07017699Recruiting
Deucravacitinib safety during pregnancy study
This study looks at how safe the medicine deucravacitinib (used for psoriasis) is during pregnancy. It compares pregnant women who took deucravacitinib to those who did not, to see if there are any effects on the baby.
La Jolla, CaliforniaAges Any age - NCT02103361Recruiting
Pregnancy registry for Stelara or Tremfya exposure
This study is a pregnancy exposure registry. It collects information to better understand pregnancy outcomes after exposure to Stelara or Tremfya (medicines used for autoimmune diseases).
La Jolla, CaliforniaAges Any age - NCT06583395Enrolling by invitation
Meditation retreat study with fitness tracker
This trial studies people attending a 7-day meditation retreat to see how meditation affects well-being. You will wear a fitness tracker and answer surveys.
Palm Desert, CaliforniaAges 21 years+
Psoriasis trials by city in California
Where these studies are running in California
Institutions with a site for the recruiting psoriasis studies listed above.
- University of California, San Francisco · 4 studies
- Center for Dermatology Clinical Research · 3 studies
- Dermatology Research Associates · 3 studies
- First OC Dermatology · 3 studies
- Northridge Clinical Trials · 3 studies
- Golden State Dermatology · 2 studies
- Investigative Site · 2 studies
- Oruka Therapeutics Investigative Site · 2 studies
What taking part in a psoriasis study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Psoriasis trials in other states
Common questions
- Are there psoriasis clinical trials in California?
- Yes. We're currently tracking 20 recruiting psoriasis studies with a site in California, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a psoriasis study in California?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in California to take part?
- Not necessarily. These studies have a site in California, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a psoriasis trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New psoriasis studies open in California regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.