Clinical trials · Pennsylvania
Sickle Cell Anemia clinical trials in Pennsylvania
We’re tracking 7 recruiting sickle cell anemia studies with a site in Pennsylvania — including Phase 1/Phase 2 and Phase 3 studies, each written for real people, not researchers.
Recruiting studies in Pennsylvania
- NCT06481306RecruitingPhase 1/Phase 2
Testing a new drug for sickle cell disease in healthy people and patients
This early-phase study tests a new drug (BMS-986470) for people with sickle cell disease who have frequent pain crises. The goal is to see if it can safely reduce crises. It includes a small group of healthy volunteers as well.
Philadelphia, PennsylvaniaAges 18 years+ - NCT03653338RecruitingPhase 1/Phase 2
Bone marrow transplant using donor blood to treat sickle cell
This trial tests a specific type of bone marrow transplant for people with sickle cell disease (or certain other blood disorders) who have had serious complications despite standard care. It aims to see if removing the patient’s immune cells and using a matched donor’s cells can improve outcomes and reduce complications.
Pittsburgh, PennsylvaniaAges 5–40 - NCT04109820Recruiting
Testing MitoQ for blood clotting activity in sickle cell
This trial studies whether MitoQ changes how your platelets (blood cells that help clot) work and how much “reactive oxygen” your body makes. It includes adults with sickle cell anemia and African American healthy volunteers to compare results.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT06941389Recruiting
Comparing stem cell transplant vs standard therapy for sickle cell disease
This study compares two treatment approaches for children with sickle cell anemia: a stem cell transplant from a matched family donor versus continuing regular disease-modifying medicines. It aims to see which treatment works better over time.
Philadelphia, PennsylvaniaAges 3–20 - NCT04208529Enrolling by invitationPhase 3
Long-term follow-up after receiving CTX001 infusion
This study follows people for a long time after they received CTX001 in an earlier (parent) study. It helps researchers learn about long-term safety and outcomes of the treatment.
Philadelphia, PennsylvaniaAges 2 years+ - NCT06290401Recruiting
Boosting self-management in teens with sickle cell disease
This study is testing a program to help adolescents with sickle cell disease better manage their health. It looks at how family, friends, and the clinic can support teens to take charge of their care.
Philadelphia, PennsylvaniaAges 13–21 - NCT06439082RecruitingPhase 3
Crizanlizumab for sickle cell pain crises
This trial tests whether crizanlizumab can reduce painful sickle cell crises (called vaso-occlusive crises or VOCs) in people with sickle cell disease who have frequent crises. It may be an option for those who still have crises despite current treatments.
Easton, PennsylvaniaAges 12–100
Sickle Cell Anemia trials by city in Pennsylvania
Where these studies are running in Pennsylvania
Institutions with a site for the recruiting sickle cell anemia studies listed above.
- Children's Hospital of Philadelphia · 3 studies
- Thomas Jefferson University Hospital · 2 studies
- UPMC Children's Hospital of Pittsburgh · 2 studies
- Local Institution
- Local Institution - 0032
- Magee-Womens Hospital of UPMC
- Spoknwrd Clinical Trials Inc.
- UPMC Hillman Cancer Center
What taking part in a sickle cell anemia study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Sickle Cell Anemia trials in other states
Common questions
- Are there sickle cell anemia clinical trials in Pennsylvania?
- Yes. We're currently tracking 7 recruiting sickle cell anemia studies with a site in Pennsylvania, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a sickle cell anemia study in Pennsylvania?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Pennsylvania to take part?
- Not necessarily. These studies have a site in Pennsylvania, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a sickle cell anemia trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New sickle cell anemia studies open in Pennsylvania regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.