Clinical trials · California
Smoking Cessation clinical trials in California
We’re tracking 11 recruiting smoking cessation studies with a site in California — including Phase 2 and Phase 3 studies, each written for real people, not researchers.
Recruiting studies in California
- NCT07111936Recruiting
Using CONNECT to help multilingual smokers get lung cancer screening
This study tests a program called CONNECT to help current smokers aged 50-80 get lung cancer screening. It aims to see if the program works well for people who speak different languages.
San Francisco, CaliforniaAges 50–80 - NCT07049757Recruiting
Healthy Family Project: Reducing tobacco smoke in Chinese American homes
This study helps Chinese American families reduce tobacco use and secondhand smoke exposure. Smokers, family members, and community health workers are all welcome.
San Francisco, CaliforniaAges 18 years+ - NCT07602699RecruitingPhase 2
Tirzepatide to Help People Quit Smoking
This study tests whether tirzepatide, a medication that helps with weight and blood sugar, can also help people quit smoking. You'd receive the medication plus standard quitting support (nicotine patches or gum and a quit-smoking app) over several months.
Los Angeles, CaliforniaAges 21–65 - NCT07129590Recruiting
Trauma-informed care to help pregnant people quit smoking
This study tests whether a trauma-informed care approach can help pregnant people who have experienced trauma to quit smoking. The study involves clinicians and patients working together to improve smoking cessation support.
San Francisco, CaliforniaAges 18 years+ - NCT06213532Recruiting
Connect to lung care study for smokers
This study, called CONNECTing to LungCare, helps current smokers who get their primary care at UCSF clinics learn about lung cancer screening. The goal is to make it easier for people to get screened and to support smokers in their health journey.
San Francisco, CaliforniaAges 18 years+ - NCT06438549Recruiting
Community health workers help pregnant smokers quit
This study tests whether adding a community health worker to your prenatal care team can help pregnant women quit smoking. It's for women who are ready to make a quit plan and are getting care at certain hospitals.
Moreno Valley, CaliforniaAges 18 years+ - NCT04949464Recruiting
Smoking quit coaching plus lung scans for people with HIV
This study tests a behavior-change program to help people with HIV quit smoking, along with routine low-dose lung CT scans to find warning signs early. It’s a feasibility study, meaning the main goal is to see if the approach is practical and acceptable, and if people can follow through.
La Jolla, CaliforniaAges 45–80 - NCT06713603Recruiting
Digital smoking cessation with motivational counseling
This study tests a digital program that uses personalized counseling over video or phone to help people stop smoking. It is for adults who smoke daily, have a primary care doctor, and can use a smartphone or computer.
San Francisco, CaliforniaAges 18 years+ - NCT05008848RecruitingPhase 3
Text message program to help rural cancer survivors quit smoking
This trial studies a text-message based program to help people who smoke quit. It targets adults in rural areas who are currently in cancer treatment and want support stopping smoking.
St. Helena, CaliforniaAges 18 years+ - NCT06432985Recruiting
Smoking Cessation Program for Veterans with Cancer
This study tests a video-based program to help Veterans who smoke and are being treated for cancer or lung cancer screening to quit. If you're a VA patient in San Francisco and currently smoke, you may be able to join.
San Francisco, CaliforniaAges 18 years+ - NCT06617312RecruitingPhase 2
Cytisinicline and brain response to smoking cues
This study tests how a medicine called cytisinicline (similar to a plant-based stop-smoking aid) affects brain activity when you see or think about smoking. It may help researchers understand how the medicine works, even if you aren't ready to quit right now.
Los Angeles, CaliforniaAges 18–65
Smoking Cessation trials by city in California
Where these studies are running in California
Institutions with a site for the recruiting smoking cessation studies listed above.
- University of California, San Francisco · 4 studies
- Zuckerberg San Francisco General Hospital and Trauma Center · 2 studies
- Keck Medicine of USC
- Loma Linda University Medical Center
- Riverside University Health System
- Saint Helena Hospital
- San Francisco VA Medical Center
- UC San Diego Moores Cancer Center
What taking part in a smoking cessation study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Smoking Cessation trials in other states
Common questions
- Are there smoking cessation clinical trials in California?
- Yes. We're currently tracking 11 recruiting smoking cessation studies with a site in California, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a smoking cessation study in California?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in California to take part?
- Not necessarily. These studies have a site in California, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a smoking cessation trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New smoking cessation studies open in California regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.