Clinical trials
Smoking Cessation clinical trials
Below are recruiting smoking cessation clinical trials, each written for real people, not researchers. We’re tracking 148 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07650721Recruiting
Training medical interns to counsel patients on quitting smoking
This study teaches medical interns how to help patients quit smoking using a proven method called the 5A model. Researchers will measure how well interns learn and apply these counseling skills.
Asyut, AssuitAges 18 years+ - NCT07602699RecruitingPhase 2
Tirzepatide to Help People Quit Smoking
This study tests whether tirzepatide, a medication that helps with weight and blood sugar, can also help people quit smoking. You'd receive the medication plus standard quitting support (nicotine patches or gum and a quit-smoking app) over several months.
Los Angeles, CaliforniaAges 21–65 - NCT07576595Recruiting
Lung Cancer Screening and Quit-Smoking Support for African Americans
This study helps African American smokers get lung cancer screening and receive support to quit smoking. Researchers will provide guidance and resources tailored to help you stop smoking and catch lung disease early if needed.
New Orleans, LouisianaAges 50–80 - NCT07487818RecruitingPhase 2/Phase 3
Vagus nerve stimulation with nicotine replacement for quitting smoking
This study tests whether adding a gentle nerve stimulation device to nicotine replacement therapy (like patches or gum) can help people quit smoking more effectively. It may be a new option for those who have struggled to quit before.
Rochester, MinnesotaAges 18 years+ - NCT07166120Recruiting
A tailored approach to help cancer patients quit smoking
This trial tests a personalized treatment plan to help people with cancer stop smoking. Researchers will see if matching you with the right medication (like the nicotine patch, lozenge, or varenicline) can improve your chances of quitting and living longer.
St Louis, MissouriAges 18–89 - NCT07129590Recruiting
Trauma-informed care to help pregnant people quit smoking
This study tests whether a trauma-informed care approach can help pregnant people who have experienced trauma to quit smoking. The study involves clinicians and patients working together to improve smoking cessation support.
San Francisco, CaliforniaAges 18 years+ - NCT06931054Recruiting
Acupuncture, ear acupressure and nicotine patches for quitting smoking
This trial tests whether adding acupuncture and ear acupressure to nicotine replacement therapy helps people quit smoking. If you smoke at least 10 cigarettes a day, are 18 or older, and can read Chinese, you may be eligible.
Hong KongAges 18 years+ - NCT07111936Recruiting
Using CONNECT to help multilingual smokers get lung cancer screening
This study tests a program called CONNECT to help current smokers aged 50-80 get lung cancer screening. It aims to see if the program works well for people who speak different languages.
San Francisco, CaliforniaAges 50–80 - NCT07099638RecruitingPhase 2
Quitting smoking with medicine and a phone app
This study tests a combination of two medicines—varenicline (Chantix) and nicotine lozenges—plus a smartphone app to help people stop smoking. You will be asked to set a quit date within the next week or two and use the app to track your progress for about 6 months.
Oklahoma City, OklahomaAges 18 years+ - NCT07080788Recruiting
Native American Pain Risk Study: Smoking Cessation
This study looks at how quitting smoking affects pain in Native American adults. Eligible participants are daily smokers who own a smartphone and do not have heart problems or chronic pain.
Tulsa, OklahomaAges 18 years+ - NCT07049757Recruiting
Healthy Family Project: Reducing tobacco smoke in Chinese American homes
This study helps Chinese American families reduce tobacco use and secondhand smoke exposure. Smokers, family members, and community health workers are all welcome.
San Francisco, CaliforniaAges 18 years+ - NCT07013968Recruiting
Mindfulness smoking cessation for abuse survivors
This study tests whether a mindfulness-based program can help people who smoke and have experienced intimate partner violence quit smoking. It offers a supportive approach to address both stress and smoking.
Rapid City, South DakotaAges 18 years+ - NCT06751927Recruiting
New ways to help you quit smoking
This study tests new strategies to help people quit smoking. It may be right for you if you smoke at least 10 cigarettes a day and are not already using a quit-smoking medication.
Chicago, IllinoisAges 18–75 - NCT06926608Recruiting
Helping Latinos quit smoking and get active
This trial is for Hispanic or Latino adults who smoke and want to quit. It tests a program that combines text messages and a wearable activity tracker to help you quit smoking and become more physically active.
Rochester, New YorkAges 18 years+ - NCT06883097Recruiting
Quitting smoking with HIV: A smoking cessation trial
This study tests whether nicotine replacement therapy (like patches or gum) can help people living with HIV quit smoking. You'll be part of a program that supports your quit attempt while you receive care for HIV.
Winston-Salem, North CarolinaAges 18 years+ - NCT06853483Enrolling by invitation
School program to help parents quit smoking
This trial tests if a school-based program can help parents stop smoking. If you are a parent who smokes at least one cigarette a day and your child is in primary 4 (4th grade), this program may offer support to help you quit.
Wuhan, HubeiAges Any age - NCT06837220Recruiting
Smoking cessation program for people in community behavioral health
This study tests a smoking cessation program designed for people who receive care at community behavioral health centers in Chicago. If you're a daily smoker interested in quitting, you may be able to join and get support to help you stop.
Chicago, IllinoisAges 18–26 - NCT06798324RecruitingPhase 4
Brain stimulation plus smoking cessation medication for quitting smoking
This trial tests whether combining brain stimulation (tDCS) with a smoking cessation medication (varenicline) helps people quit smoking. You would attend daily visits for two weeks.
Toronto, OntarioAges 18–85 - NCT06693700Recruiting
Using an air quality monitor to help make your home smoke-free
This study tests whether an indoor air quality monitor can help people keep their homes smoke-free. It is for MSK patients who currently smoke and want to reduce smoke exposure indoors.
Basking Ridge, New JerseyAges 18 years+ - NCT04725617Recruiting
Smoking-quit program for people with HIV and sleep issues
This study tests a wellness-based smoking-cessation program (including the stop-smoking medicine varenicline) for people living with HIV who want to quit. It aims to help you reduce or stop smoking while monitoring safety, sleep, and mental health during the program.
Phoenix, ArizonaAges 18–75 - NCT06584929Recruiting
Rural smoking cessation app study
This study tests a smartphone-based program to help people who smoke at least 5 cigarettes a day quit. It focuses on adults in rural areas who want to stop smoking using their own device.
Minneapolis, MinnesotaAges 21 years+ - NCT06570122Recruiting
Phone-based help for parents who smoke
This study tests if a mobile phone program can help parents quit smoking. You may be able to join if you live in Zhuhai, smoke every day, and use WeChat on your smartphone.
Zhuhai, GuangdongAges 18 years+ - NCT06556433Recruiting
Smoking Cessation Trial with Family Support and Financial Incentives
This study tests whether offering financial rewards to both you and a family member can help you quit smoking. You will be asked to quit smoking, and both you and your nominated family member can earn payments for meeting certain milestones.
Anchorage, AlaskaAges 18 years+ - NCT06544811Recruiting
Smokefree Native: Smartphone quit support for American Indians
This trial tests a smartphone-based program to help American Indian adults quit smoking. If you are ready to try quitting and have daily access to a smartphone, you may be able to join for free support.
Minneapolis, MinnesotaAges 18 years+
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Smoking Cessation trials by city
Studies with a site in or near these metro areas.
Smoking Cessation trials by state
Studies with a site anywhere in these states.
Common questions
- Are there clinical trials for smoking cessation?
- Yes. Clin2 currently lists 148 recruiting smoking cessation studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a smoking cessation trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a smoking cessation trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.