Clinical trials
Suicide clinical trials
Below are recruiting suicide clinical trials, each written for real people, not researchers. We’re tracking 271 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05786066RecruitingPhase 2
Test whether blocking AMPA changes ketamine’s suicide relief
This study looks at whether an “AMPA receptor blocker” changes how ketamine affects suicidal thoughts in people with depression that hasn’t improved with usual treatments. If you qualify, you may receive ketamine and the study medicine, while continuing your regular mental health care.
West Haven, ConnecticutAges 21–65 - NCT05920252Recruiting
Phone-based suicide risk support for teens in DBT
This trial tests whether a smartphone tool can help reduce suicide risk for teens who are already in an intensive therapy program (DBT). It may help you or your family recognize risk earlier and use skills more consistently between sessions.
New York, New YorkAges 13–18 - NCT05925322Recruiting
Social reward therapy for depression-related suicidal thoughts
This study looks at whether “social reward” psychotherapy can change brain activity and reduce suicidal thoughts in adults ages 50–80 who also have major depression. You may be offered psychotherapy along with brain scans to see how your brain responds over time.
New York, New YorkAges 50–80 - NCT05995678Recruiting
STEP Home Workshop for veterans adjusting to civilian life
This pilot study tests a workshop called STEP Home to help veterans who recently left the military and are having trouble readjusting. The goal is to improve their transition and reduce suicide risk.
Boston, MassachusettsAges 18–65 - NCT07303959Recruiting
Sleep treatment for teens after a hospital stay
This study tests a sleep program called Sleepio to help teens who have been in the hospital for suicide risk and also have trouble sleeping. The goal is to see if improving sleep can help them feel better and stay safer.
Piscataway, New JerseyAges 14–18 - NCT06338904Recruiting
Suicide prevention program for adults over 50
This trial tests a brief problem-solving program delivered in different formats to help adults over 50 who are having thoughts of suicide. The goal is to see which format works best to reduce suicidal thoughts.
Santiago de Compostela, A CoruñaAges 50 years+ - NCT06462196Recruiting
Study of Depression, Bipolar Disorder & Suicide Risk
This study looks at how depression, bipolar disorder, and suicide risk naturally change over time. It aims to better understand these conditions so doctors can improve treatments.
Bethesda, MarylandAges 18–120 - NCT06480500RecruitingPhase 2
Online therapy and IV ketamine for severe depression with suicide risk
This study tests whether adding an online therapy (i-CBT) to intravenous (IV) ketamine is better than IV ketamine alone for people with treatment-resistant depression who are also thinking about suicide. You'll receive either ketamine or a comparison drug (midazolam), plus the online therapy, in a hospital setting.
Toronto, OntarioAges 21–65 - NCT07346014Recruiting
Sleep therapy for college students at risk of suicide
This study tests if improving sleep can help college students who are already getting mental health treatment for suicidal thoughts. You will try light therapy or sleep schedule changes to see if it reduces suicide risk.
Pittsburgh, PennsylvaniaAges 18–25 - NCT06854224RecruitingPhase 2
Testing a sleep drug for suicide risk in veterans with depression
This trial tests whether a medication called suvorexant (used for sleep) can help lower suicide risk in veterans who have major depression and have attempted suicide before. The study aims to see if blocking a brain chemical called orexin reduces suicidal thoughts.
The Bronx, New YorkAges 18–70 - NCT06891300RecruitingPhase 2/Phase 3
Ketamine for Suicidal Thoughts in Depression
This study tests if ketamine can help reduce suicidal thoughts in people with major depression. You'll receive ketamine treatment and be monitored closely.
Ottawa, OntarioAges 18–65 - NCT07025720Recruiting
Brain stimulation for depression and suicide risk in young people
This study tests a new type of brain stimulation called TMS (transcranial magnetic stimulation) for young people ages 15-25 who are having serious depression and suicidal thoughts. The goal is to see if this treatment can help reduce risk and improve mood.
Sacramento, CaliforniaAges 15–25 - NCT07043231Recruiting
Creative tools for discussing suicide with kids
This trial tests if creative materials help healthcare professionals talk about suicide with children and teens. It aims to improve support for young people at risk.
GhentAges 18 years+ - NCT07051200Recruiting
Support program for young adults after a mental health crisis
This study offers a program to support young adults who recently faced a mental health crisis. It aims to help you recover by providing inspiration, support, and empowerment after a hospital stay.
Dallas, TexasAges 18–27 - NCT07150832Recruiting
I-CARE app for teens after a suicide crisis
This trial tests a digital program called I-CARE to support teens aged 12-17 who have had a suicide attempt, suicidal thoughts, or self-harm. It aims to help them while they wait for inpatient psychiatric care.
New Haven, ConnecticutAges 12–17 - NCT07170657Recruiting
Teen Recovery Support Program
This program helps teens ages 15 to 18 who have recently been in the hospital or emergency room for suicidal thoughts or depression. It provides support and guidance to help you recover and feel stronger.
Dallas, TexasAges 15–18 - NCT07302295Recruiting
How COVID-19 affected suicidal behavior in kids
This study looks at how the COVID-19 pandemic affected suicidal behavior in children and teens. Researchers want to compare episodes that happened during the pandemic (2020-2022) with those just before (2018-2019) to understand if there was a change.
BronAges 8–18 - NCT07339189Recruiting
AI Suicide Prevention for Older Adults With HIV
This trial tests a smartphone-based AI program designed to help people with HIV who have had suicidal thoughts. It aims to reduce suicide risk by teaching coping skills through text-based conversations.
Newark, New JerseyAges 50 years+ - NCT07346638Recruiting
Trauma therapy for women with suicidal thoughts
This trial tests a group therapy program called BEAR for women who have experienced trauma and are currently having suicidal thoughts. The program aims to help reduce distress and improve coping.
Stanford, CaliforniaAges 18–75 - NCT07417826Recruiting
Therapy for suicide risk in eating disorders
This trial tests a therapy that combines cognitive-behavioral techniques with a digital tool to help women with eating disorders who have had recent suicidal thoughts or attempts. It aims to reduce suicide risk and improve mental health.
Sabadell, BarcelonaAges 18–65 - NCT07523490Recruiting
Understanding Suicide Risk in Mood Disorders
This research study aims to identify factors that increase suicide risk in people with mood disorders (like depression or bipolar disorder). By completing questionnaires, you'll help doctors better understand and prevent suicide in patients with these conditions.
Tianjin, Tianjin MunicipalityAges 16–60 - NCT07450105Enrolling by invitation
Intensive DBT for Teens Who Self-Harm or Feel Suicidal
This study tests whether an intensive type of therapy called dialectical behavior therapy (DBT) can help teenagers who are hurting themselves or feeling suicidal. It focuses on young people with signs of borderline personality disorder, and includes parents or caregivers in the treatment.
BergenAges 14–17 - NCT03736538Enrolling by invitationPhase 1
Nitrous oxide for suicidal thoughts in depression
This Phase 1 study tests whether breathing nitrous oxide can safely reduce suicidal thoughts in adults with major depression. It may help people whose depression is causing moderate to severe suicidal thinking, by studying a fast-acting treatment approach.
St Louis, MissouriAges 18–65 - NCT06529029RecruitingPhase 2/Phase 3
Comparing new low-pulse ECT to standard ECT for depression
This trial tests a new type of seizure therapy (low amplitude pulse seizure therapy) against the standard ultra-brief right unilateral ECT for people with severe depression, including those with suicidal thoughts. The goal is to see which treatment works better.
Grand Rapids, MichiganAges 18–90
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Common questions
- Are there clinical trials for suicide?
- Yes. Clin2 currently lists 271 recruiting suicide studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a suicide trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a suicide trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.