Clinical trials
Supplementation clinical trials
Below are recruiting supplementation clinical trials, each written for real people, not researchers. We’re tracking 685 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05705414RecruitingEarly Phase 1
Amino acid supplement during dialysis to improve energy in kidney disease
This early-stage study tests whether taking amino acids during hemodialysis can help people with end-stage kidney disease feel better and maintain strength. It may help by supporting nutrition during dialysis, but it’s mainly meant to gather early safety and benefit information.
San Antonio, TexasAges 18–64 - NCT04288635Recruiting
Testing a nutrient supplement for energy problems in septic shock
This study looks at whether a metabolite (nutrient) supplement can help the body’s cells work better when someone is in septic shock. It is done in the ICU, and it may benefit people with sepsis who still have poor circulation and high lactate levels despite standard treatment.
Angers, Maine et LoireAges 18 years+ - NCT06766604Recruiting
Super-GDF9 for egg maturation in women with PCOS
This study tests a protein called Super-GDF9 added to the lab process of maturing eggs from very small follicles. It may help women with PCOS produce more usable eggs for in vitro fertilization (IVF).
Ho Chi Minh CityAges 18–38 - NCT05477901Recruiting
Cash transfers study in mothers and children
This study checks whether receiving cash support (a government cash transfer program) helps children’s brain and development. Families will be assessed, and children must be able to take part in activities that may include an MRI scan.
New York, New YorkAges 23–45 - NCT07479173Recruiting
How a study ingredient affects protein digestion in healthy adults
This trial tests whether a study ingredient called P24 changes how your body breaks down and uses protein from a meal. It may help researchers understand ways to support muscle health as we age.
Davis, CaliforniaAges 45–75 - NCT06776016RecruitingPhase 2
Dietary supplement for radiation-related rectal injury
This trial tests a dietary supplement to help heal damage inside the rectum caused by pelvic radiation therapy. If you have mild to moderate rectal bleeding but no signs of cancer recurrence, you may be able to join.
Guangzhou, GuangdongAges 18–75 - NCT07752628Enrolling by invitation
F-60 safety trial for children with severe acute malnutrition
This trial tests a new food supplement (F-60) for children hospitalized with severe acute malnutrition. It aims to see if F-60 is safe and can help children recover.
DhakaAges 6 months–4.9 years - NCT07564674Recruiting
How Your Body Processes Broccoli Extract Supplements
This study tests how well your body absorbs and uses broccoli extract supplements. Researchers want to understand if these supplements deliver their plant-based benefits effectively, which could help improve future supplement design.
Corvallis, OregonAges 18–60 - NCT07583251RecruitingPhase 1
Safety of a supplement for mild memory loss
This trial tests an oral supplement called gamma glutamylcysteine (GGC) in people with mild cognitive impairment (MCI) to see if it is safe and well-tolerated. It may help by supporting the body's natural defenses against cell damage.
Pittsburgh, PennsylvaniaAges 55–80 - NCT06606704Recruiting
Strength bands and creatine for healthy older adults
This study tests whether a simple home exercise program using resistance bands, combined with a creatine supplement, can help improve muscle strength and health in older adults who are not already doing regular strength training.
Regina, SaskatchewanAges 50 years+ - NCT06337812Recruiting
Fiber supplement study for heart failure and diabetes
This study tests whether adding a daily fiber supplement can improve health in people with heart failure and type 2 diabetes. Participants take the supplement for several weeks to see if it helps manage symptoms and blood sugar.
Ann Arbor, MichiganAges 18 years+ - NCT05090267Recruiting
Gut-brain treatments for alcohol use and memory changes
This study tests whether gut-brain–targeted treatments (including probiotics and stimulation of a nerve) can improve thinking and inflammation-related health in people who use alcohol. You may be able to join if you have memory/thinking problems and meet specific medical limits, including HIV immune system levels.
Coral Gables, FloridaAges 35–70 - NCT07222306Enrolling by invitation
Cannabis, brain inflammation, and suicidal thoughts brain imaging study
This study uses brain scans to see how cannabis affects inflammation and suicidal thoughts. You may join if you're already in a related study and can safely undergo MRI and PET scans.
Detroit, MichiganAges 19–69 - NCT06956612Recruiting
Dietary nitrate supplements and your oral health
This trial tests whether taking dietary nitrate supplements can improve oral health in healthy adults. It may help you understand how simple diet changes could support your mouth's natural defenses.
NewcastleAges 18–65 - NCT06936137RecruitingPhase 3
Probiotics for weight gain from antipsychotic medication
This trial tests if taking a probiotic supplement can help prevent or reduce weight gain caused by certain antipsychotic medications. It is for people with schizophrenia who have gained significant weight after starting these medications.
Cairo, AbbassiaAges 18–45 - NCT06813261Recruiting
GLYLO supplement trial for aging in postmenopausal women
This trial tests whether a supplement called GLYLO can reduce markers of aging related to sugar damage in postmenopausal women. It may help if you are between 45 and 65, have some extra belly fat or higher blood sugar, and are not taking certain medications.
Novato, CaliforniaAges 45–65 - NCT06845501Recruiting
Purine supplements for AICA-ribosiduria
This trial tests whether adding purines (natural substances found in foods) to your diet can help treat AICA-ribosiduria, a rare genetic condition. It may be a safe and simple therapy option for you.
Saint-EtienneAges 3 years+ - NCT06746805Recruiting
Ketone drink and exercise fuel use in trained cyclists
This study tests if drinking a ketone supplement before exercise changes how your body uses carbs for fuel. It may help trained cyclists and triathletes understand fuel efficiency.
Maastricht, LimburgAges 18–50 - NCT06623981Recruiting
Treating maternal depression in an urban asthma clinic
This study tests whether treating depression in Black mothers of children with asthma can improve both the mother's mood and the child's asthma. It offers support for mothers who are feeling down and may help their child's asthma get better.
Washington D.C., District of ColumbiaAges Any age - NCT06673082Enrolling by invitation
Zinc as a new therapy for cow milk allergy in children
This study tests if adding zinc to standard treatment helps children with cow milk protein allergy. It aims to see if zinc can improve their symptoms and make them feel better.
GizaAges 1 month–12 years - NCT06553729Recruiting
Vitamin D and prebiotic supplement for blood sugar during pregnancy
This trial tests whether taking a combination of vitamin D and a prebiotic can help manage blood sugar levels in pregnant women at high risk for gestational diabetes. It may offer a simple way to support a healthy pregnancy.
Zhanjiang, GuangdongAges 18–45 - NCT06428097RecruitingPhase 1
Thyroid hormone before heart transplant
This study tests whether giving a thyroid hormone supplement called levothyroxine before a heart transplant can help with recovery. It is for people already listed for a heart transplant who do not have thyroid problems.
San Francisco, CaliforniaAges 18 years+ - NCT06275542Enrolling by invitation
Removing breathing tube without standard monitoring device
This study tests if it is safe to remove the breathing tube after surgery based on oxygen levels without using a special nerve monitor. It may help find a simpler method for deciding when to take the tube out.
YogyakartaAges 18–60 - NCT06062017Recruiting
Potassium, hydration, and heart health in young adults
This study looks at how potassium and hydration affect heart and kidney health in healthy young adults. It may help you understand your own health and contribute to new knowledge about preventing disease.
Auburn, AlabamaAges 18–30
Hear when a new Supplementation trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for supplementation?
- Yes. Clin2 currently lists 685 recruiting supplementation studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a supplementation trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a supplementation trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.