Clinical trials
Temporomandibular Disorders (TMD) clinical trials
Below are recruiting temporomandibular disorders (tmd) clinical trials, each written for real people, not researchers. We’re tracking 45 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07075276Recruiting
Comparing a new growth factor treatment to standard care for jaw joint pain
This study tests a new treatment for a common jaw joint problem called disc displacement. It compares a concentrated growth factor from your own blood to standard care to see which helps more with pain and jaw movement.
Damietta, New DamiettaAges 18–45 - NCT06617494Recruiting
Study of pain control in chronic jaw pain
This study looks at how well the body's natural pain control system works in people with long-term jaw pain (TMD). It compares people with and without jaw pain to better understand why some have trouble turning off pain signals.
Minneapolis, MinnesotaAges 18–74 - NCT06782165Recruiting
Long-term follow-up of jaw joint surgery
This study follows up on patients who had jaw joint (TMJ) surgery. It looks at how the joint is doing after 6 months to predict long-term results. It may help understand if earlier checkups can guide care.
HuddingeAges 18 years+ - NCT06265636Recruiting
Nerve stimulation for jaw pain and function in TMD
This trial tests whether gentle electrical stimulation of a nerve in your jaw can reduce pain and improve chewing, talking, and mouth opening for people with temporomandibular joint disorder (TMD).
Alcorcón, MadridAges 18–65 - NCT06602375Recruiting
Physical therapy and exercise for jaw pain
This study tests if adding manual physical therapy and exercise to standard dental care helps active-duty service members with jaw pain (temporomandibular disorders). It aims to see if this combination works better than dental care alone.
Fort Sam Houston, TexasAges 18–55 - NCT06627855Recruiting
Fascial stretch method for jaw pain relief
This study tests a hands-on technique called the fascial distortion model to see if it works better than a sham treatment for reducing jaw, face, or neck pain. It may help if you have had a jaw disorder for at least 3 months.
Merkez, Karabük ProvinceAges 18–64 - NCT06659991RecruitingEarly Phase 1
Pain and daily tasks in jaw joint disorder
This study tests how pain from a jaw joint disorder (TMD) affects your ability to do daily tasks. You'll track your pain and activities on your smartphone to help researchers understand the link.
Minneapolis, MinnesotaAges 21–65 - NCT06932406Recruiting
Personality and self-help for jaw pain
This study tests whether a self-management program for jaw and face pain works differently in people with different personalities. You will learn techniques to manage your pain at home.
Valencia, ValenciaAges 18–65 - NCT06975709Recruiting
Link between jaw pain and sleep problems
This study looks at how jaw joint disorders (TMJ) are related to sleep issues like insomnia, sleep apnea, or restless legs. If you have a sleep disorder, you may help researchers understand the connection.
Milan, ItalyAges 18 years+ - NCT06977100Recruiting
Journaling study for jaw pain with other chronic pain conditions
This study tests if a journaling program can help people with jaw pain and at least one other chronic pain condition (like fibromyalgia, IBS, or migraines). You will write about your thoughts and feelings to see if it reduces pain and improves well-being.
Gainesville, FloridaAges 18–80 - NCT07018791RecruitingPhase 3
Art-based pain test for jaw joint disorder patients
This trial tests if using art can help measure pain in people with temporomandibular joint disorders (TMD). It may offer a new way to understand and manage your pain without surgery.
Jeddah, Mecca RegionAges 18 years+ - NCT07211711Recruiting
Splint therapy for tinnitus linked to jaw joint issues
This trial tests if a custom mouthpiece (occlusal splint) can relieve ringing in the ears (tinnitus) that started along with jaw or face pain (TMD). It aims to see if stabilizing the jaw helps reduce both the noise in your ears and the discomfort.
São Paulo, São PauloAges 18 years+ - NCT07373184Recruiting
Virtual planning for jaw joint replacement
This study looks back at past jaw joint (TMJ) replacement surgeries to see how virtual planning helped. If you already had this surgery at a specific hospital between 2010 and 2025, you might be included.
LundAges Any age - NCT07474662Recruiting
Online vs. in-person physiotherapy for jaw muscle pain
This trial compares online physiotherapy sessions with face-to-face visits to see which works better for treating jaw muscle pain (myalgia). It aims to find a more convenient way to get care for this common condition.
Budapest, Pest CountyAges 18 years+ - NCT07507734Recruiting
Splint and exercise therapy for jaw joint pain
This trial tests whether a custom mouth splint combined with jaw exercises can reduce pain in the jaw joint (TMJ). It may help people who have had jaw joint pain for at least 3 months.
Istanbul, TuzlaAges 18–65 - NCT07639944Recruiting
REN Device Study for Jaw Pain and Headaches
This study tests whether a treatment called REN can help reduce headaches and jaw pain caused by temporomandibular disorders (TMD). You would use the REN device at home on your smartphone or tablet over several months.
Ridgeland, MississippiAges 12 years+ - NCT07566936Enrolling by invitation
Digital vs. Traditional Splints for Jaw Joint Disorders
This study compares two types of custom-made jaw splints—one designed using digital technology and one made the traditional way—to see which better relieves jaw pain and improves mouth opening in people with temporomandibular disorder (TMD), a common condition affecting the jaw joint.
Islamabad, IslamabadAges 18–40 - NCT07129096Enrolling by invitation
Digital relaxation training for jaw pain
This study tests if a digital relaxation program can help reduce jaw pain caused by temporomandibular disorders (TMD). It may be a good option if you have jaw muscle or joint pain and want to try a non-drug approach.
OuluAges Any age - NCT06912438Enrolling by invitation
Emotional release after dry needling for jaw and head pain
This study tests whether a dry needling technique (trigger point needling) can help release emotional tension and reduce pain from muscle knots in the head and neck. It may be a good option if you have jaw or headache pain related to muscle tightness.
Tel Aviv, IsraelAges 18 years+ - NCT05183503Enrolling by invitation
Study of pain, stress, anxiety, and depression in jaw disorder
This study looks at how chronic jaw pain from temporomandibular disorder (TMD) relates to stress, anxiety, and depression in adults. Your results may help researchers better understand what affects symptoms and how people respond to care.
WroclawAges 18–80 - NCT05272488Recruiting
Manual therapy plus vagus nerve stimulation for jaw muscle pain
This trial tests whether combining hands-on jaw treatment with a vagus nerve stimulator can reduce jaw muscle pain and improve jaw movement. It may help people whose jaw pain has been present recently and who have not had recent physiotherapy.
Alcalá de Henares, MadridAges 18 years+ - NCT06782178Recruiting
Comparing two jaw joint procedures for limited mouth opening
This study compares two minimally invasive procedures (arthroscopy using a tiny camera vs. arthrocentesis using a needle to flush the joint) to see which works better for people with a displaced jaw disc that limits mouth opening. It might help you if simple treatments haven't worked.
HuddingeAges 18 years+ - NCT06813040Recruiting
TMS therapy for jaw and face pain
This trial tests if repetitive transcranial magnetic stimulation (a non-invasive brain stimulation technique) can reduce long-lasting jaw and face pain caused by temporomandibular disorders. It might help people who have had pain for over six months and rate their pain as high.
CoimbraAges 18 years+ - NCT07147764Recruiting
Pain education plus physiotherapy for jaw pain
This trial compares two treatments for long-lasting jaw or face pain: physiotherapy alone versus physiotherapy combined with education about how pain works. It aims to find which approach helps more.
Istanbul, KavacikAges 18–65
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Common questions
- Are there clinical trials for temporomandibular disorders (tmd)?
- Yes. Clin2 currently lists 45 recruiting temporomandibular disorders (tmd) studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a temporomandibular disorders (tmd) trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a temporomandibular disorders (tmd) trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.