Clinical trials
Tooth Diseases clinical trials
Below are recruiting tooth diseases clinical trials, each written for real people, not researchers. We’re tracking 39 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05902351Recruiting
Study of the natural course of Charcot-Marie-Tooth disease
This study looks at how Charcot-Marie-Tooth disease (CMT) or related inherited nerve conditions change over time. It may help researchers better understand what to expect and guide future treatments.
New York, New YorkAges Any age - NCT01805869Recruiting
Teeth removal study using leftover tissue for research
This study looks at people who need wisdom tooth (third molar) removal and collects the leftover tissue after extraction. The goal is to use these samples to help dental research, while making sure the procedure can be done safely.
Bethesda, MarylandAges 16–50 - NCT07476365Recruiting
Finding new markers for early CMT1A disease
This study looks for new markers of early Charcot-Marie-Tooth 1A (CMT1A) disease using blood tests and special MRI scans. It aims to help understand how the disease progresses and may lead to better treatments.
GöttingenAges 10–30 - NCT07570459Recruiting
Understanding Tremor in Charcot-Marie-Tooth Disease
This study examines tremor (involuntary shaking) in people with Charcot-Marie-Tooth disease, a genetic nerve condition that affects the legs and feet. Researchers will compare people with CMT who have tremor to healthy volunteers to better understand this symptom.
Göttingen, Lower SaxonyAges 18–65 - NCT04010188Recruiting
Study comparing people with Charcot-Marie-Tooth and healthy controls
This study follows people who have Charcot-Marie-Tooth disease (CMT) and compares them with people without it. It aims to better understand CMT, using both clinical symptoms and genetic test results, which may help future care.
FuzhouAges Any age - NCT07152197Recruiting
Resistance Exercise for Charcot-Marie-Tooth Disease
This trial tests whether resistance exercises (like lifting weights with your legs) can help people with Charcot-Marie-Tooth disease. It is for young adults aged 15 to 29 who can move their ankle enough to do strength training.
Temuco, La AraucaníaAges 15–29 - NCT07049588Recruiting
Finding early signs of Charcot-Marie-Tooth 1A
This trial looks for new markers of Charcot-Marie-Tooth 1A (CMT1A) early in the disease. Researchers hope to find signs that can help diagnose and track the disease better, which could lead to better treatments in the future.
MarseilleAges 10–30 - NCT07570446Recruiting
Autonomic Function in Charcot-Marie-Tooth Disease
This study examines how autonomic nerves (the nerves that control automatic body functions like heart rate and blood pressure) are affected in people with CMT (Charcot-Marie-Tooth disease), a genetic nerve disorder. Understanding this may help improve treatment and quality of life for CMT patients.
Göttingen, Lower SaxonyAges 18–65 - NCT07726043Recruiting
Rehab with vibration therapy for balance in CMT1A
This trial tests whether adding a special vibration device to an intensive rehab program helps improve balance in people with Charcot-Marie-Tooth disease type 1A. If you are between 18 and 65 and have mild to moderate leg weakness, you may be able to join.
MarseilleAges 18–65 - NCT07447557RecruitingPhase 1/Phase 2
Gene therapy study for Charcot-Marie-Tooth type 4J (CMT4J)
This trial tests a gene therapy medicine (ELP-02) given through a spinal tap for children and young adults with a specific genetic form of CMT (CMT4J). It aims to slow or stop the disease from getting worse.
Palo Alto, CaliforniaAges 3–20 - NCT07226297Enrolling by invitationPhase 1/Phase 2
Personalized treatment for GARS1-related CMT2D
This trial tests a personalized medicine designed for a single person with a specific genetic mutation (GARS1) that causes Charcot-Marie-Tooth disease type 2D. The treatment is an antisense oligonucleotide, a custom-made molecule that targets the faulty gene.
Houston, TexasAges 13 years+ - NCT06794489Recruiting
Tracking CMT with biomarkers over time
This study is looking for people with Charcot-Marie-Tooth disease (a nerve condition) and healthy volunteers to track long-term changes in the body. Researchers want to see if certain biomarkers (measurable signs) can help predict how CMT progresses over time.
Göttingen, Lower SaxonyAges 18–65 - NCT06778590Recruiting
Comparing two ways to remove lower wisdom teeth
This study compares two methods for removing lower wisdom teeth before they are fully grown. It uses a special ultrasound tool (piezoelectric) versus traditional surgical tools to see which is gentler and leads to faster healing.
CatanzaroAges 14–24 - NCT07393997Recruiting
Tooth transplant with platelet-rich fibrin for young patients
This trial tests a tooth transplant method that uses a healthy tooth from elsewhere in your mouth to replace a missing tooth. A special protein-rich material (platelet-rich fibrin) is placed around the new tooth to help it heal and grow roots. It's designed for children, teens, and young adults who cannot get dental implants.
BariAges 10–80 - NCT01193075Recruiting
Study of how Charcot-Marie-Tooth (CMT) develops over time
This study follows people who have Charcot-Marie-Tooth disease (CMT) and compares them with people without nerve disease. The goal is to better understand different CMT types and how symptoms and nerve test results change over time.
Los Angeles, CaliforniaAges Any age - NCT06203093Recruiting
CMT sample collection for stem cell research
This study collects blood, saliva, or skin samples from people with Charcot-Marie-Tooth disease (CMT) and healthy volunteers. The samples are used to create stem cells (iPSCs) and build a biobank to help researchers understand and treat CMT.
New York, New YorkAges 5 years+ - NCT06328712RecruitingPhase 1/Phase 2
Cell therapy for Charcot-Marie-Tooth type 1A (CMT1A)
This trial tests a new cell therapy called EN001 for people with CMT1A. It aims to see if the treatment is safe and can help with nerve function and muscle weakness.
GyeongjuAges 19 years+ - NCT07136844Recruiting
Walking and arm movement study for nerve and muscle conditions
This study uses motion analysis to understand walking and arm function in adults with certain neurological or metabolic diseases. The goal is to find patterns that help doctors better manage these conditions.
LiègeAges 18 years+ - NCT06520137Recruiting
Wisdom tooth removal and gum disease study
This study looks at how removing an impacted upper wisdom tooth affects gum health. It may help people who need this tooth removed and do not have advanced gum disease.
Siena, Italy/SIAges 19–64 - NCT06708468Recruiting
Personalized training for rare neuromuscular disorders
This study tests a personalized exercise program for people with rare neuromuscular diseases like FSHD, DM1, or CMT to see if it improves their physical function and quality of life.
BergenAges 18–70 - NCT06929676Enrolling by invitation
Tooth mobility after gum disease treatment and splinting
This trial tests how much tooth movement improves after deep cleaning and splinting (connecting loose teeth) in people with advanced gum disease. It may help if you have loose front teeth from gum disease.
Piracicaba, São PauloAges 18 years+ - NCT06666816Recruiting
Watching changes in walking for muscle and nerve diseases
This study watches how people with certain muscle or nerve diseases walk over time. It may help doctors understand changes in walking patterns and is open to adults who can walk and have a genetic diagnosis of a neuromuscular condition.
Bosisio Parini, LeccoAges 18–75 - NCT07461896Recruiting
Nerve function study in Charcot-Marie-Tooth and related neuropathies
This study looks at how nerves work and their structure in people with Charcot-Marie-Tooth disease, CIDP, or anti-MAG neuropathy. It may help doctors better understand these conditions.
MilanAges 18 years+ - NCT01193088Recruiting
Study genetics to find who modifies Charcot-Marie-Tooth (CMT)
This study looks at DNA changes in families with Charcot-Marie-Tooth (CMT), especially a known gene duplication called PMP22. It aims to understand what other genetic factors may change how CMT shows up, which could help future diagnosis and care.
Los Angeles, CaliforniaAges Any age
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Common questions
- Are there clinical trials for tooth diseases?
- Yes. Clin2 currently lists 39 recruiting tooth diseases studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a tooth diseases trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a tooth diseases trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.