Clinical trials
Stress Disorders, Traumatic clinical trials
Below are recruiting stress disorders, traumatic clinical trials, each written for real people, not researchers. We’re tracking 279 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05646732Recruiting
Brain scan and stimulation study for PTSD in adults
This study uses MRI brain scans and a noninvasive brain stimulation (TMS) to better understand PTSD in the brain. It may help researchers identify brain patterns linked to PTSD and how brain stimulation affects them.
Palo Alto, CaliforniaAges 18–55 - NCT05788302Recruiting
Studying prolonged exposure for PTSD and how it helps
This trial studies how a therapy called “prolonged exposure” works for people with post-traumatic stress disorder (PTSD). You may be able to join if you have PTSD, are interested in starting prolonged exposure, and meet other safety and participation rules.
Boston, MassachusettsAges 18 years+ - NCT05927324Recruiting
Video-based therapy coaching for mothers and young children
This trial tests a coach-guided, video feedback therapy method to help mothers and their young children. It is meant for mothers (biological) of children aged 12 to 54 months who have lived together most of the child’s life.
Lausanne, Canton of VaudAges 18–50 - NCT05929911Recruiting
Talk therapy for PTSD in people living with HIV
This trial tests whether trauma-focused psychodynamic talk therapy can reduce symptoms of post-traumatic stress disorder (PTSD) in people who also live with HIV. It may help by offering structured therapy alongside stable medication.
The Bronx, New YorkAges 18–65 - NCT05934162Recruiting
Internet cognitive therapy for PTSD symptoms
This study tests whether therapist-guided cognitive-behavior therapy delivered over the internet can reduce PTSD symptoms. If you have PTSD and can use Swedish online materials, you may be able to take part without traveling to clinic visits.
StockholmAges 18 years+ - NCT06002633Recruiting
Alcohol effects and brain responses in PTSD
This study explores how people with PTSD respond to alcohol and how their brains handle approach or avoidance situations. You may participate if you drink alcohol occasionally and are between 21 and 60 years old.
Austin, TexasAges 21–60 - NCT06035809Recruiting
Smart treatment study for PTSD using brain activity feedback
This study tests a new therapy called SMART, which uses brain imaging to help regulate arousal linked to PTSD. It aims to see if combining brain feedback with therapy reduces PTSD symptoms.
London, OntarioAges 18–65 - NCT06044675RecruitingPhase 2
MDMA plus therapy for PTSD – a study with a partner
This study tests whether MDMA, combined with a type of talk therapy called CBCT (cognitive behavioral conjoint therapy), is more effective than CBCT alone for treating PTSD. You and a close partner will both participate in therapy sessions and take MDMA together.
Toronto, OntarioAges 18–80 - NCT06111976Recruiting
TMS plus reactivation therapy for resistant PTSD
This trial tests if adding a type of brain stimulation (TMS) to a memory reactivation therapy can reduce PTSD symptoms that haven't improved with standard antidepressants. If you have persistent PTSD, this study could offer a new treatment option.
ParisAges 18–65 - NCT06117306RecruitingPhase 3
MDMA therapy and PTSD in veterans
This study tests if combining MDMA with therapy can help veterans with PTSD. The treatment involves taking MDMA during therapy sessions while focusing on past trauma.
San Diego, CaliforniaAges 18–64 - NCT06162741Recruiting
Brief mindfulness training for Veterans in primary care
This study tests whether brief mindfulness training offered in VA primary care can help Veterans with symptoms of PTSD, depression, or anxiety. It aims to see if this approach works well in everyday clinic settings.
Phoenix, ArizonaAges 18 years+ - NCT06194851RecruitingPhase 2
Oxytocin nasal spray plus couples therapy for Veterans with PTSD
This study tests whether a nasal spray of oxytocin (a natural hormone) can boost the effects of a brief couples therapy for Veterans with PTSD. You and your partner would receive either the spray or a placebo (inactive spray) during therapy sessions to see if it helps reduce PTSD symptoms and improve relationship satisfaction.
San Diego, CaliforniaAges 18 years+ - NCT06203106Recruiting
NYSCF Scientific Discovery Biobank
This study collects blood, saliva, or skin samples from people with certain neurological conditions and from healthy volunteers to help researchers better understand and find treatments for these diseases.
New York, New YorkAges 4 weeks+ - NCT06266364Recruiting
Vagus nerve stimulation for treatment-resistant PTSD
This study tests if stimulating the vagus nerve with an implanted device can help adults with chronic PTSD who haven't gotten better with standard treatments. You would have the device implanted and then follow the study plan for several months.
Austin, TexasAges 22–79 - NCT06310109Recruiting
PICU Diaries to Support Children and Families
This study tests whether a special diary, kept by families during the PICU stay, helps children and their parents cope better after leaving the hospital. It is for children who needed a breathing machine for more than 48 hours.
RomeAges Up to 19 years - NCT06332209Recruiting
Telehealth vs. in-person therapy for trauma in Puerto Rican youth
This trial compares two ways of giving a type of therapy called Trauma-Focused Cognitive Behavioral Therapy (TF-CBT) to children and teens in Puerto Rico who have been through a traumatic event and have post-traumatic stress symptoms. One group receives therapy in person at a clinic, and the other group receives therapy through video calls (telehealth), to see which works better.
Charleston, South CarolinaAges 7–18 - NCT06386003RecruitingPhase 2
Psilocybin and talk therapy for chronic PTSD
This trial tests whether a medication called psilocybin (the active ingredient in magic mushrooms) can help people with long-term PTSD when combined with a specific type of talk therapy. The goal is to see if this approach reduces PTSD symptoms more than therapy alone.
Toronto, OntarioAges 18–65 - NCT06394284RecruitingPhase 3
MDMA therapy for PTSD in male Israeli veterans
This study tests whether MDMA (the drug in Ecstasy) can help male Israeli veterans with PTSD feel better, especially if their symptoms are related to moral injury. It involves therapy sessions and monitoring to see how the drug affects your brain and emotions.
JerusalemAges Any age - NCT06419959Recruiting
NightWare watch for better sleep and heart health in veterans with PTSD
This study tests if a special watch (NightWare) can help veterans with PTSD who have nightmares sleep better and improve heart health. The watch vibrates gently during nightmares to reduce them without waking you up.
Aurora, ColoradoAges 22–88 - NCT06479447Recruiting
Patient-reported PTSD screening study
This trial is testing a simple way to check for PTSD symptoms using patient-reported questionnaires. It aims to help people who haven't been screened recently get the care they need.
Chicago, IllinoisAges 18 years+ - NCT06548126Recruiting
Online parenting program for displaced families
This trial tests an online parenting program for caregivers who have experienced forced displacement. It aims to support families with children aged 6 to 12 by teaching positive parenting skills.
Tempe, ArizonaAges 18 years+ - NCT06589505RecruitingPhase 2/Phase 3
Software app for treating PTSD
This trial is testing a software program (like an app) designed to help treat PTSD. It may be an option if your PTSD is related to a past traumatic event and you haven't already tried several trauma-focused therapies.
Yamanashi, HokkaidoAges 18–65 - NCT05732155RecruitingPhase 2
MDMA-assisted therapy for Israeli veterans with PTSD
This study tests whether MDMA (the active ingredient in Ecstasy) given in therapy sessions can help Israeli special forces veterans with PTSD and moral injury. Participants will receive MDMA alongside talk therapy to see if it reduces symptoms.
AfulaAges 18 years+ - NCT06635486Recruiting
Mental health support for Venezuelans in Lima
This study offers mental health support to Venezuelan adults living in Lima who are feeling anxious, depressed, or have experienced trauma. It will check if you have signs of depression, anxiety, or post-traumatic stress and provide help if you do.
LimaAges 18 years+
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Common questions
- Are there clinical trials for stress disorders, traumatic?
- Yes. Clin2 currently lists 279 recruiting stress disorders, traumatic studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a stress disorders, traumatic trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a stress disorders, traumatic trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.