Treatment
Pegvaliase clinical trials
We’re tracking 4 recruiting studies that include Pegvaliase, each written for real people, not researchers, below.
Recruiting studies
- NCT05579548Recruiting
Study of Pegvaliase use in pregnancy and breastfeeding for PKU
This study looks at how taking Pegvaliase during pregnancy and breastfeeding affects pregnancy, baby health, and early infant outcomes in people with PKU. It may help improve care guidance for patients and babies exposed to Pegvaliase before birth.
Wilmington, North CarolinaAges Any age - NCT05813678Recruiting
Long-term safety monitoring for Palynziq in PKU
This study tracks the long-term safety of Palynziq (pegvaliase) in people with PKU as they take the medicine over time. It may help you and other patients understand long-term side effects and whether Palynziq stays safe.
Aurora, ColoradoAges Any age - NCT06305234Recruiting
Long-term immune response study for Palynziq PKU treatment
This long-term study checks how the immune system reacts to Palynziq (a treatment for PKU) over time. It involves extra blood tests for people already in another PKU study called 165-501.
Aurora, ColoradoAges Any age - NCT07477691RecruitingPhase 4
Immune therapy during Palynziq treatment for PKU
This study tests whether combining a drug called methotrexate with Palynziq (a treatment for PKU) can help control immune responses and improve treatment outcomes. It may be an option for adults with PKU who have never used Palynziq or who have not reached target blood levels after at least 24 weeks.
Los Angeles, CaliforniaAges 18–65
What Pegvaliase is being studied for
Conditions with recruiting Pegvaliase studies.
Common questions
- Are there clinical trials studying Pegvaliase?
- Yes. Clin2 currently lists 4 recruiting studies that include Pegvaliase, drawn from the U.S. registry and rewritten for real people so you can see what each is testing and who it's for.
- How do I know if I qualify for a Pegvaliase trial?
- Each study lists its own eligibility criteria — rules about condition, age, and prior treatments. On every Clin2 trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Is Pegvaliase an approved treatment?
- A drug being studied in a trial may be investigational (still being tested) or already approved and being studied for a new use. Each study page explains what phase it's in. Clin2 does not provide medical advice — talk with your doctor about whether Pegvaliase or a specific trial is right for you.
Related treatments
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. A drug appearing here is being studied in a trial and may be investigational. Talk with your doctor about whether a specific treatment or trial is right for you.