Understanding the genetics of autoinflammatory diseases
Part of Eyes & vision, Genetic & congenital, Pain, Skin clinical trials.
This study collects genetic samples and medical histories from people with autoinflammatory diseases (like Familial Mediterranean Fever), their relatives, and healthy volunteers to understand how these conditions run in families and what causes them. Participation mainly involves providing a mail-in DNA sample.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are at least one month old (healthy volunteers must be at least one year old)
- You are willing to provide a mail-in genetic sample and have your medical history reviewed
- You have a medical history that might suggest an autoinflammatory disease, are related to someone with one, or are a healthy volunteer
- You or your parent/guardian can understand the study and sign a consent form
- You do not have another medical condition that would confuse the study results
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study compares physical activity levels in teenagers with familial Mediterranean fever (FMF), a condition causing repeated fevers and inflammation, to healthy teens. The goal is to understand how the disease affects daily movement and to guide better care.
This study follows people with rare “autoinflammatory” conditions and sometimes their blood relatives to understand why symptoms happen and how they change over time. It may help by improving diagnosis and care for these conditions, using stored samples and genetic testing.
This study looks for genes that may be linked to autoimmune diseases by comparing the DNA of people with these conditions to healthy family members or volunteers. If you have an autoimmune disease or are a healthy person interested in helping research, this study may help scientists understand why these diseases run in families.
This study looks at the gut bacteria (microbiome) in people with autoinflammatory diseases. It may help researchers understand how bacteria in the gut affect inflammation and find better ways to treat these conditions.
This study looks for genes linked to autoinflammatory diseases like VEXAS syndrome. You or your family member can join by mailing in a blood or saliva sample to help researchers better understand these conditions.
This study looks at how genes and symptoms relate in children with Familial Mediterranean Fever (FMF). It will help doctors understand the condition better and may lead to more personalized care.
Hear when a new Familial Mediterranean Fever trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.