Study of rare inflammatory conditions to learn what causes them
Part of Genetic & congenital, Immune system & allergy, Skin clinical trials.
This study follows people with rare “autoinflammatory” conditions and sometimes their blood relatives to understand why symptoms happen and how they change over time. It may help by improving diagnosis and care for these conditions, using stored samples and genetic testing.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You (or your child) are age 2–99 for NIH visits, or newborn–99 if doing remote visits with mailed samples
- You agree to store your blood/other samples for future research
- You agree to genetic testing on the samples
- You have a doctor who manages your health conditions day to day
- For participants with symptoms: you have an autoinflammatory condition pattern, or a known disease-causing gene change related to these conditions
- If you’re a blood relative or healthy volunteer: you must fit the study group rules and not have the affected participant’s qualifying condition
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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