Clin2
NCT00001539Possibly a fitRecruiting

Understanding Symptoms After Lyme Disease Treatment

Lyme Disease

Part of Infections clinical trials.

This research study examines why some people continue to have symptoms months after being treated for Lyme disease. Researchers will compare patients with ongoing symptoms to people who recovered well, to better understand what causes lasting problems and how to help.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
700 people
Ages
13 years to 99 years
Study type
Observational

Who can take part

  • Age 13 or older (if you have suspected post-treatment Lyme disease) or age 18+ (if you're a control participant)
  • Confirmed or probable Lyme disease diagnosed by a doctor (for main patient group)
  • Completed recommended antibiotic treatment for Lyme disease
  • Symptoms lasting at least 6 months after finishing antibiotics (for main patient group)
  • No other medical explanation for your current symptoms
  • No serious autoimmune diseases, chronic illnesses, or use of immune-suppressing medications

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT00028080Recruiting
Evaluation and treatment for active Lyme disease

This study evaluates and treats people who currently have active Lyme disease, as defined by CDC criteria. It aims to provide expert care and follow-up while studying the disease.

Bethesda, Maryland
NCT06397794Recruiting
Pregnancy and parenting with Lyme disease study

This study explores the experiences of people who had Lyme disease during pregnancy or had ongoing Lyme symptoms throughout their pregnancy. By sharing your story in a recorded interview, you can help doctors and researchers better support parents with Lyme disease.

Washington D.C., District of Columbia
NCT06026969Recruiting
Study on Lyme disease and baby development after pregnancy exposure

This study looks at how Lyme disease during pregnancy might affect a baby's development. It involves questionnaires and possibly an MRI of the baby's brain, done at a visit or remotely.

Washington D.C., District of Columbia
NCT05036707Recruiting· Phase 1/Phase 2
Study how tick bites change immune responses

This study looks at how a person’s immune system responds after exposure to Ixodes (black-legged) tick bites. It aims to better understand the body’s early immune reaction after tick exposure, using blood tests and small skin samples.

Bethesda, Maryland
NCT07703787Not yet recruiting
Immune monitoring for Lyme disease treatment

This study looks at how your immune system responds to the bacteria that causes Lyme disease. It may help doctors better understand the disease and improve treatment. The trial includes people with a specific form of Lyme called acrodermatitis chronica atrophicans (a skin condition) and healthy volunteers.

Strasbourg
NCT07500506Recruiting· Phase 3
Safety of a fifth dose of the Lyme disease vaccine

This study is for people who have already received four doses of the Lyme vaccine (VLA15) in a previous study. It tests whether a fifth dose is safe and helps the body build more protection against Lyme disease.

Bangor, Maine

Hear when a new Lyme Disease trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.