Apheresis for certain immune system gene problems
Part of Immune system & allergy clinical trials.
This trial studies whether an apheresis procedure (removing blood cells through a machine) can help people with specific inherited immune system conditions. Participants will also receive filgrastim to help move certain blood-forming cells for collection.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Be age 18 to 40
- Have one of these diagnoses: DOCK8 deficiency, LAD-1 with low CD18, or GATA2 deficiency
- Have kidney and liver blood tests within required limits
- Have enough veins for the procedure, or agree to a temporary central line if needed
- Be able to sign consent and follow study instructions
- If you can become pregnant: have a negative urine pregnancy test before starting filgrastim
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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