Clin2
NCT01311258Possibly a fitRecruiting

Tracking leftover cancer cells in AML or high-risk MDS

Acute Myeloid LeukemiaMyelodysplastic Syndrome

Part of Blood & lymphatic, Cancer clinical trials.

This study checks for “minimal residual disease,” meaning tiny numbers of leukemia cells that can remain after treatment. Results may help doctors better monitor your response and risk of relapse in AML or high-risk MDS.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
400 people
Ages
18 years and older
Study type
Observational

Who can take part

  • You’re being evaluated for acute myeloid leukemia (AML) or high-grade myelodysplastic syndrome (high-risk MDS).
  • Your bone marrow test shows more than 10% blasts (immature blood cells).
  • You haven’t had chemo or similar cancer-killing treatment for AML/high-risk MDS in the last 3 months (except hydroxyurea or Revlimid).
  • You haven’t had a stem cell transplant from a different person (allogeneic transplant) for this disease.
  • You must be at least 18 and able to sign consent and participate safely.
  • You don’t have other serious illnesses or major decision-making limits that would block consent or treatment.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06301425Recruiting
Transplant study for high-risk AML based on MRD response

This trial tests whether adjusting a stem cell transplant (allo-HSCT) based on a marker called MRD (minimal residual disease) improves outcomes for people with a high-risk type of acute myeloid leukemia (AML). It's for those who are newly diagnosed, between 16 and 65, and have early remission after 1 or 2 rounds of chemotherapy.

Beijing
NCT05564390Recruiting· Phase 2
MyeloMATCH screening to match you to AML or MDS treatment

This study screens people with newly suspected acute myeloid leukemia (AML) or myelodysplastic syndrome (MDS) to see which treatment approach fits best—either a specific study treatment or standard care. It may help by directing you to the right option and by sharing your blood/bone marrow samples for research.

Birmingham, Alabama
NCT06928662Recruiting· Phase 1/Phase 2
Chemo, radiation, and donor stem cell transplant for high-risk blood cancers

This trial tests a strong chemotherapy and radiation combo followed by a donor stem cell transplant for people with aggressive blood cancers (like AML or MDS) that haven't responded to earlier treatments or came back. It aims to help prevent the cancer from returning.

Seattle, Washington
NCT04726241Recruiting· Phase 1/Phase 2
Testing blood and bone marrow samples in young leukemia patients

This trial looks at blood and bone marrow samples from children and teens whose leukemia has come back or is hard to treat. The goal is to better understand the disease and guide future options for these patients.

Birmingham, Alabama
NCT06439199Recruiting
Blood protein study in non-intensive chemotherapy for AML and MDS

This study looks at certain proteins in the blood (called FLT3 ligand and IL6) of people being treated for blood cancers like AML, MDS, or CMML. The goal is to understand how these proteins change during non-intensive chemotherapy, which may help doctors better personalize treatment.

Nantes, Loire-Atlantique
NCT07867704Not yet recruiting
New lab test for acute myeloid leukemia

This study tests a new lab method to screen for acute myeloid leukemia (AML), including a rare subtype called acute promyelocytic leukemia. It may help doctors diagnose and classify AML more quickly and accurately.

Hear when a new Acute Myeloid Leukemia trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.