Studying KSHV inflammatory syndrome (KICS)
Treatments studied
Part of Immune system & allergy, Infections clinical trials.
This study tracks people with KICS, a condition caused by KSHV (a virus related to Kaposi sarcoma). It aims to understand the syndrome better and may lead to future treatments.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older.
- You have at least two symptoms from different groups (like fever, fatigue, low blood counts, or enlarged lymph nodes or organs) that doctors think might be caused by KICS.
- You have been exposed to KSHV (through living in an endemic area, male-to-male sex, or have evidence of KSHV in your blood or tissues), or have Kaposi sarcoma or a related cancer.
- You do not have a confirmed diagnosis of KSHV-associated multicentric Castleman disease (MCD) by biopsy.
- You are not pregnant and agree to use contraception if needed.
- You do not have any other serious condition that would make this study unsafe.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests a drug called pacritinib for people with KSHV-associated multicentric Castleman disease (MCD) or KSHV-associated inflammatory cytokine syndrome (KICS). It aims to see if the drug can help control symptoms and inflammation caused by these conditions.
This study follows people with Kaposi sarcoma to learn more about the disease and how it changes over time. It may help doctors better understand and treat KS in the future.
This study collects and analyzes tumor tissue to learn what drives certain cancers and growths linked to viruses, HIV, and immune system problems. Results may help researchers understand disease causes and point to better future treatments.
This trial tests an experimental drug (CYT107) that boosts the immune system to help fight Kaposi sarcoma in people with HIV who have a low CD4 count despite good HIV treatment. It aims to see if the drug can improve KS tumors and quality of life.
This study looks at how KSHV-associated multicentric Castleman disease naturally progresses over time, without necessarily testing a new treatment. It may help doctors better understand the disease and what changes to watch for, which could guide future care.
This study collects tissue and blood samples from people who have or have been exposed to certain viruses (HIV, KSHV, HPV, EBV, or HTLV-1) or who have developed cancer or precancerous skin lesions. The samples help researchers understand how these viruses may lead to cancer.
Hear when a new KSHV Inflammatory Cytokine Syndrome (KICS) trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.